1 00:00:00,050 --> 00:00:03,250 Tim : Emergency medicine is such a humbling fulfilling you know, 2 00:00:03,309 --> 00:00:05,199 difficult path that we have chosen. 3 00:00:05,229 --> 00:00:09,293 We see people at their worst and sometimes they can rise to the occasion 4 00:00:09,293 --> 00:00:12,563 and be at their best, but we have to also rise to the occasion, be at our 5 00:00:12,563 --> 00:00:14,393 best and give them what they need. 6 00:00:14,393 --> 00:00:16,673 And if that's information, if that's reassurance, if that's 7 00:00:17,093 --> 00:00:18,833 guidance that's what we try to do. 8 00:00:21,343 --> 00:00:24,083 Sam (2): Hi everyone, and welcome to another episode of EMplify. 9 00:00:24,103 --> 00:00:25,853 I'm your host, Sam Ashoo. 10 00:00:26,053 --> 00:00:29,876 Before we dive into this month's episode, I want to say happy 11 00:00:29,876 --> 00:00:35,933 holidays . It is that time of year again, and with so much joy I say. 12 00:00:36,468 --> 00:00:38,568 Thank you for being a subscriber. 13 00:00:38,718 --> 00:00:43,458 And if you're not a subscriber, no better time than the present eb medicine.net. 14 00:00:43,668 --> 00:00:48,738 Get a free $50 Amazon gift card for spending $300 or more in the 15 00:00:48,738 --> 00:00:51,618 store and use that CME funding. 16 00:00:51,673 --> 00:00:54,793 Emergency medicine practice, pediatric emergency medicine practice, 17 00:00:54,823 --> 00:00:59,293 evidence-based urgent care, the EKG course, the laceration course, the abscess 18 00:00:59,293 --> 00:01:01,573 course, the interactive clinical pathways. 19 00:01:01,573 --> 00:01:04,753 So many things to help you in your practice. 20 00:01:04,843 --> 00:01:09,763 Go spend some money, get a gift card, become a subscriber, and have 21 00:01:09,763 --> 00:01:14,948 a wonderful Holiday . And now let's jump into this month's episode. 22 00:01:16,559 --> 00:01:17,279 Tim : Good morning, Sam. 23 00:01:17,279 --> 00:01:18,039 I'm Tim Horeczko. 24 00:01:18,059 --> 00:01:19,409 I'm very happy to be here with you. 25 00:01:19,409 --> 00:01:23,249 I'm from Harbor, UCLA where I am the program director for the Pediatric 26 00:01:23,249 --> 00:01:24,419 Emergency Medicine Fellowship. 27 00:01:24,479 --> 00:01:28,829 And more importantly, and to your own heart, I am one of the co-editors in chief 28 00:01:28,889 --> 00:01:30,844 of pediatric emergency medicine practice. 29 00:01:31,084 --> 00:01:34,054 So I'm very happy to be here with you and maybe even give you a little 30 00:01:34,054 --> 00:01:37,099 bit of a behind the scenes of how we were able to develop this article. 31 00:01:37,799 --> 00:01:38,309 Sam: Awesome. 32 00:01:38,369 --> 00:01:41,189 Thank you so much for agreeing to be on the podcast. 33 00:01:41,189 --> 00:01:44,969 Today we are talking about the pediatric emergency medicine 34 00:01:44,969 --> 00:01:48,599 practice article from November, 2025. 35 00:01:48,599 --> 00:01:53,609 This one is specifically on the management of measles, mumps, rubella, and varicella, 36 00:01:53,939 --> 00:01:59,369 which you would think would be mostly historical, but in light of recent events, 37 00:01:59,369 --> 00:02:01,829 I thought the timing was actually perfect. 38 00:02:01,859 --> 00:02:06,089 This was authored by Dr. Sarah Cavalero was an excellent review, 39 00:02:06,089 --> 00:02:07,679 I think, of all of those diseases. 40 00:02:07,949 --> 00:02:11,819 And so thank you for agreeing to be on the podcast to discuss it with us. 41 00:02:12,139 --> 00:02:17,029 It's an interesting topic, and I wanna start by saying in like my 20 42 00:02:17,029 --> 00:02:21,679 years of clinical practice, I have seen varicella, I've seen chickenpox 43 00:02:21,799 --> 00:02:27,579 I think I've seen maybe two cases of measles and maybe a handful of mumps. 44 00:02:27,769 --> 00:02:30,679 Never seen, at least that I know of a case of rubella. 45 00:02:30,929 --> 00:02:34,799 And certainly the cases of measles I saw were like very mild, and 46 00:02:34,799 --> 00:02:36,179 it was kind of questionable. 47 00:02:36,179 --> 00:02:38,759 And we got like a dermatologist involved and they're like, yeah, sure. 48 00:02:38,759 --> 00:02:41,309 It could be like a mild, you know, and somebody who's been partially 49 00:02:41,309 --> 00:02:42,929 vaccinated or something of that sort. 50 00:02:43,209 --> 00:02:47,019 So this is an interesting time because in our country here in the 51 00:02:47,019 --> 00:02:51,559 United States, there are outbreaks of measles in several areas. 52 00:02:51,559 --> 00:02:54,259 Pretty large outbreaks of thousands of children involved. 53 00:02:54,259 --> 00:02:54,359 And so. 54 00:02:55,059 --> 00:02:58,929 If you're working in emergency medicine, these are diseases that we 55 00:02:58,929 --> 00:03:03,379 previously learned about in textbooks and took for board exams that now we 56 00:03:03,379 --> 00:03:05,509 have to learn to recognize clinically. 57 00:03:05,779 --> 00:03:11,929 And I would say most of the physicians who worked in the pre vaccine era or in 58 00:03:11,929 --> 00:03:14,779 the newly vaccinated era are all retired. 59 00:03:14,779 --> 00:03:17,719 And so we've kinda lost that clinical knowledge. 60 00:03:17,719 --> 00:03:20,869 We don't have a good core memory for what these things look like. 61 00:03:21,089 --> 00:03:24,869 And I think today I would miss many of these things when they first 62 00:03:24,869 --> 00:03:25,919 come to the emergency department. 63 00:03:25,919 --> 00:03:29,229 So, I really wanna say thanks for agreeing to be on the podcast to talk about it. 64 00:03:29,259 --> 00:03:32,619 'cause I think this is going to be a very important discussion and very 65 00:03:32,619 --> 00:03:33,969 pertinent to many of our listeners. 66 00:03:34,409 --> 00:03:34,799 Tim : Thank you, Sam. 67 00:03:34,799 --> 00:03:36,145 I love what you do on the podcast. 68 00:03:36,150 --> 00:03:37,800 You really bring it to life for people. 69 00:03:37,800 --> 00:03:41,670 And speaking of which, you know, Dr. Cavalero took some oldies but goodies 70 00:03:41,670 --> 00:03:45,870 and really made it very accessible to us and refreshed, I think, in our 71 00:03:45,870 --> 00:03:49,780 memories especially, you know, recent epidemics, what our role is in the 72 00:03:49,780 --> 00:03:53,680 emergency department from a public health standpoint, in addition to trying to 73 00:03:53,680 --> 00:03:55,330 help that individual in front of us. 74 00:03:55,750 --> 00:03:57,627 And you mentioned some good points about. 75 00:03:58,327 --> 00:04:02,407 It's sort of like our, I would say the evolution of our experience over time. 76 00:04:02,407 --> 00:04:05,477 I am gen X as well and so, you know, you see a little bit of the 77 00:04:05,477 --> 00:04:09,527 bridging of the generations where, we would see pre varicella vaccine. 78 00:04:09,527 --> 00:04:10,487 that's chicken pox, right? 79 00:04:10,487 --> 00:04:11,597 That's there it is. 80 00:04:11,987 --> 00:04:15,827 And I'm teaching my residents and fellows and we often will, if we see a case, it 81 00:04:15,827 --> 00:04:18,447 will be the attenuated version, right? 82 00:04:18,447 --> 00:04:21,777 This is somebody who would've already gotten the vaccine maybe, or even a 83 00:04:21,777 --> 00:04:26,140 full -blown case, but you almost have to couch and say, in my day, you know, 84 00:04:26,200 --> 00:04:27,370 no one wants to hear that phrase. 85 00:04:28,070 --> 00:04:31,310 But I think it's important that we can continue to share our experience because 86 00:04:31,370 --> 00:04:35,330 we never know when these oldies but goodies will come back and they are right 87 00:04:35,330 --> 00:04:37,220 there in front of our face right now. 88 00:04:37,920 --> 00:04:42,600 Sam: Yeah, and I think a lot of us, at least I did not have a good appreciation 89 00:04:42,600 --> 00:04:45,030 for the severity of the diseases. 90 00:04:45,030 --> 00:04:46,890 You know, we just assume, oh, we have a vaccine for it. 91 00:04:46,890 --> 00:04:50,700 But we forget that the reason why we put so much effort into developing a vaccine 92 00:04:50,700 --> 00:04:55,110 is because these were diseases that cause significant morbidity or mortality. 93 00:04:55,380 --> 00:04:59,760 So the epidemiology section is always a fun place for me to 94 00:04:59,760 --> 00:05:01,609 start, because I like the numbers. 95 00:05:01,829 --> 00:05:05,759 And measles, I think of all of these is probably the most 96 00:05:05,759 --> 00:05:08,289 striking the pre-vaccine era. 97 00:05:08,559 --> 00:05:13,359 The, data we have from then said anywhere from 15 to 60,000 cases of 98 00:05:13,359 --> 00:05:18,379 blindness 2 million deaths per year due to pneumonia or encephalitis as 99 00:05:18,379 --> 00:05:23,139 complications of measles and young children less than five years old, and 100 00:05:23,139 --> 00:05:27,579 adults over 20 were the ones who actually had the highest morbidity historically. 101 00:05:27,949 --> 00:05:27,999 And. 102 00:05:28,699 --> 00:05:33,979 In 2000, the United States was among 42% of countries that said 103 00:05:33,979 --> 00:05:35,449 they had eliminated measles. 104 00:05:35,669 --> 00:05:37,834 Meaning there's , no spread in the communities , or 105 00:05:37,834 --> 00:05:39,274 country or person to person. 106 00:05:39,554 --> 00:05:41,774 And then we've sort of backtracked since then. 107 00:05:41,774 --> 00:05:47,384 So COVID kind of caused a large decrease in community vaccination efforts. 108 00:05:47,514 --> 00:05:50,764 And then since then there have been some other political factors that 109 00:05:50,764 --> 00:05:52,204 have even reduced them even further. 110 00:05:52,204 --> 00:05:56,114 And now our cases are actually over 1500 cases in 2025. 111 00:05:56,504 --> 00:06:01,014 And two deaths already, which is historically kinda unheard of in the last 112 00:06:01,224 --> 00:06:03,984 25 years here in the US from measles. 113 00:06:04,339 --> 00:06:05,029 Tim : Yeah, it is crazy. 114 00:06:05,029 --> 00:06:07,729 You know, we, sort of joke about first world problems when we have 115 00:06:07,729 --> 00:06:09,229 inconveniences that we don't like. 116 00:06:09,229 --> 00:06:13,429 And we historically thought of outbreaks of measles, mumps, rubella, 117 00:06:13,429 --> 00:06:16,929 et cetera, as a developing country problem because of course we have 118 00:06:16,929 --> 00:06:21,159 all of the wonderful resources and blessings to be in a developed country 119 00:06:21,209 --> 00:06:22,679 that we benefit from constantly. 120 00:06:22,709 --> 00:06:26,849 And so we're sort of seeing this funny thing where we're not appreciating 121 00:06:26,849 --> 00:06:27,809 what's right there in front of us. 122 00:06:27,809 --> 00:06:31,739 These are the, again, tried and true vaccines that have proven themselves 123 00:06:31,979 --> 00:06:33,509 to be very safe and effective. 124 00:06:33,979 --> 00:06:38,209 of course, you can make arguments that there are always reportable complications 125 00:06:38,209 --> 00:06:42,829 of any intervention that we have, but, you know, it's just as good as clean water. 126 00:06:43,529 --> 00:06:45,299 are you gonna test every time we take a sip? 127 00:06:45,299 --> 00:06:48,069 I don't know about that, but I think the thing is that we have to 128 00:06:48,369 --> 00:06:51,601 be careful about how we communicate that to our people, right? 129 00:06:51,601 --> 00:06:55,201 Because the patient in front of us just cares about trying to get better and 130 00:06:55,201 --> 00:06:56,911 trying to survive whatever the problem is. 131 00:06:56,911 --> 00:07:00,061 They'll come in worried about measles, mumps, rubella, varicella. 132 00:07:00,511 --> 00:07:05,471 So we, you know, we as passionate as we can be about our hats of public 133 00:07:05,471 --> 00:07:10,221 health and hats of emergency medicine, I think that our messaging has to be very 134 00:07:10,521 --> 00:07:12,291 attuned to the patient in front of us. 135 00:07:12,351 --> 00:07:14,671 There's some people that are very resistant, right? 136 00:07:14,671 --> 00:07:17,461 They're very hesitant and they are not gonna listen to anything you say. 137 00:07:17,461 --> 00:07:20,611 And the moment that you start to go into a diatribe, they will shut 138 00:07:20,611 --> 00:07:24,181 off any communications and then anything that you wanna help them 139 00:07:24,181 --> 00:07:27,601 for, supportive care, whatever it is, even just please stay away from 140 00:07:27,881 --> 00:07:31,111 pregnant women, from immunocompromised, et cetera, they won't listen. 141 00:07:31,111 --> 00:07:36,577 So I've changed my interaction with patients in that I will ask them if 142 00:07:36,577 --> 00:07:40,917 the, let's just say the topic, the discussion gets to be around vaccinations. 143 00:07:41,317 --> 00:07:43,792 I try to see where they are, meet them where they are, and I will 144 00:07:43,792 --> 00:07:47,116 say, you know, what questions would you have about X, Y, and z about 145 00:07:47,116 --> 00:07:48,934 vaccinations ? I don't have any questions. 146 00:07:49,204 --> 00:07:49,324 Okay. 147 00:07:49,324 --> 00:07:51,994 Well, I'm always here to help and I appreciate that you've Read about 148 00:07:51,994 --> 00:07:53,224 or heard about different things. 149 00:07:53,224 --> 00:07:55,654 I would just encourage you to make sure that you've heard from 150 00:07:55,654 --> 00:07:58,764 various sources and sources are referenced and that you can trust. 151 00:07:58,824 --> 00:08:02,734 And I'm very happy to speak with you about anything that you want to clarify. 152 00:08:03,134 --> 00:08:07,204 There are some times there's more poignant where it is case of measles 153 00:08:07,204 --> 00:08:10,414 that comes in and really we need to make sure that we have given some 154 00:08:10,414 --> 00:08:12,284 post-exposure prophylaxis to the family. 155 00:08:12,984 --> 00:08:16,074 it'll be more pointed and that we can talk about different things. 156 00:08:16,074 --> 00:08:19,074 Sam, you tell me what direction you'd like to go in, but what I would say 157 00:08:19,074 --> 00:08:22,814 about that is the connection with public health, these are all reportable diseases 158 00:08:22,894 --> 00:08:23,094 Sam: Mm-hmm. 159 00:08:23,414 --> 00:08:27,704 Tim : so, you know, every jurisdiction's gonna have their own way of reporting it. 160 00:08:27,704 --> 00:08:31,554 In Los Angeles County, we have a pretty robust reporting mechanism. 161 00:08:32,084 --> 00:08:34,674 But you know, measles, mumps, rubella, regardless of where 162 00:08:34,674 --> 00:08:35,814 you live, are all reportable. 163 00:08:36,024 --> 00:08:40,254 Varicella in general is mostly reportable if for hospitalizations or deaths. 164 00:08:40,664 --> 00:08:44,119 But it comes into play when I have to worry about the little kid that needs to 165 00:08:44,119 --> 00:08:46,069 be isolated from measles that goes home. 166 00:08:46,339 --> 00:08:49,099 It's not just about that little kid, it's about every little child 167 00:08:49,099 --> 00:08:52,249 or every little person involved because the r nought right. 168 00:08:52,249 --> 00:08:57,124 The R zero meaning the average number of cases of infectivity 169 00:08:57,279 --> 00:08:58,419 that one person can cause. 170 00:08:58,419 --> 00:09:01,899 So little Johnny is three years old and he has measles. 171 00:09:01,899 --> 00:09:04,329 He goes home to his family of five to seven. 172 00:09:04,479 --> 00:09:09,619 He's gonna infect 12 to 18 people, little Johnny, which means that, 173 00:09:09,719 --> 00:09:13,769 Johnny and Jane and whoever else will then infect another 12 to 18 people. 174 00:09:14,469 --> 00:09:16,569 That is what we like to call an exponential growth. 175 00:09:16,939 --> 00:09:19,969 Just as an example, we think we poo poo measles sometimes because, ah, 176 00:09:19,969 --> 00:09:22,729 it's, you know, natural immunity or whatever people wanna say. 177 00:09:23,209 --> 00:09:26,359 But when we think about the R noughts, the infectivity, the average number of 178 00:09:26,359 --> 00:09:30,927 cases that one person can infect , we worry about things like tb, tbs only six. 179 00:09:31,317 --> 00:09:32,937 We worry about things like COVID. 180 00:09:32,942 --> 00:09:33,777 COVID is only four. 181 00:09:34,167 --> 00:09:35,307 We worry about the common cold. 182 00:09:35,307 --> 00:09:37,287 That's two to three people that you're gonna infect. 183 00:09:37,957 --> 00:09:40,017 Ebola, nobody likes Ebola. 184 00:09:40,687 --> 00:09:42,097 three is the rnot. 185 00:09:42,167 --> 00:09:42,287 Sam: Hmm. 186 00:09:42,307 --> 00:09:43,837 Tim : one case is gonna affect three people. 187 00:09:43,867 --> 00:09:44,677 Do we like that? 188 00:09:44,677 --> 00:09:48,137 No, but just the magnitude. 189 00:09:48,557 --> 00:09:53,217 And then also I think our individual responsibility of living in a society 190 00:09:53,217 --> 00:09:57,307 is that in order to have herd immunity for something like measles, which I'm 191 00:09:57,307 --> 00:10:00,547 focusing on measles because this is probably the highest morbidity of the 192 00:10:00,877 --> 00:10:02,107 diseases we're talking about today. 193 00:10:02,457 --> 00:10:07,417 You need 90% herd immunity in a community in order for us to prevent an outbreak. 194 00:10:07,417 --> 00:10:12,757 Trying to get 90% of adult humans in this world to do anything is hard. 195 00:10:12,992 --> 00:10:13,282 Sam: Yeah. 196 00:10:13,447 --> 00:10:15,067 Tim : I can get 90% of 'em to breathe. 197 00:10:15,307 --> 00:10:16,357 That's probably all I could do. 198 00:10:16,860 --> 00:10:18,240 So that's tough. 199 00:10:18,240 --> 00:10:23,650 So it's a lot of like stepwise multifactorial, multi-tiered counseling 200 00:10:23,650 --> 00:10:25,367 and public health interventions. 201 00:10:25,367 --> 00:10:27,587 And our just every day just trying to connect with our 202 00:10:27,587 --> 00:10:29,867 patients to get it to be 90%. 203 00:10:29,867 --> 00:10:33,017 And then when we have other factors against us, man, we have to be 204 00:10:33,017 --> 00:10:36,647 so ready to diagnose on site. 205 00:10:36,827 --> 00:10:40,500 And now these diseases are all clinical diagnoses that your public health 206 00:10:40,672 --> 00:10:46,702 mechanism may ask you to do a PCR or to do some serologies to verify, but we should 207 00:10:46,702 --> 00:10:51,682 all be ready to diagnose these on site and be able to counsel people even if you 208 00:10:51,682 --> 00:10:55,072 don't feel, you mentioned about, you know, hey, there's some cases of maybe measles. 209 00:10:55,402 --> 00:10:56,392 The maybe measles. 210 00:10:56,452 --> 00:10:59,722 I am gonna treat like measles until proven otherwise and say, listen, this 211 00:10:59,722 --> 00:11:03,712 is what we think it is and we're gonna be careful for everyone involved. 212 00:11:04,412 --> 00:11:04,862 Sam: Yeah. 213 00:11:04,922 --> 00:11:05,162 Yeah. 214 00:11:05,162 --> 00:11:06,512 So many good points there. 215 00:11:06,782 --> 00:11:10,342 And you know, that's just measles, but the author talked about the 216 00:11:10,342 --> 00:11:15,822 epidemiology of mumps causing permanent deafness or death due to encephalitis. 217 00:11:16,102 --> 00:11:19,442 And that's something that's not so far removed historically. 218 00:11:19,442 --> 00:11:23,692 The author mentioned an outbreak on college campuses in 2014 and one in 219 00:11:23,692 --> 00:11:28,412 the National Hockey League in 2014 because of how highly infectious it is. 220 00:11:28,722 --> 00:11:32,022 And you know, thankfully neither of those resulted in deaths but those are 221 00:11:32,022 --> 00:11:33,732 outbreaks that had to be contained. 222 00:11:33,782 --> 00:11:35,792 And probably involved emergency departments. 223 00:11:36,122 --> 00:11:40,322 And then rubella a disease that at least, again, I don't think I've 224 00:11:40,682 --> 00:11:45,102 had the privilege of treating in the emergency department, but primarily 225 00:11:45,102 --> 00:11:48,252 devastating to fetuses, right? 226 00:11:48,252 --> 00:11:52,372 So this is kind of in pregnancy where it's the most lethal but it causes a lot 227 00:11:52,372 --> 00:11:56,386 of neonatal death, spontaneous abortions and then congenital rubella syndrome 228 00:11:56,666 --> 00:12:00,416 which, you know, again here, the data in the article says in the US between 229 00:12:00,416 --> 00:12:06,266 1964 and 1965, before vaccination, we had 12 and a half million people 230 00:12:06,326 --> 00:12:13,366 with rubella, 11,000 women miscarrying 2100 newborn deaths and 20,000 infants 231 00:12:13,456 --> 00:12:15,316 born with congenital rubella syndrome. 232 00:12:15,326 --> 00:12:15,546 Tim : Yes. 233 00:12:15,616 --> 00:12:20,956 Sam: Uh, And since 2012, 10 cases, so we've gone from like 20,000 in 234 00:12:20,956 --> 00:12:27,346 a year to 10 cases in over 20 years because of the vaccine efficacy in 235 00:12:27,346 --> 00:12:32,741 that scenario which is just a, an outstanding number to think about in my 236 00:12:32,741 --> 00:12:35,171 brain for how effective that has been. 237 00:12:35,567 --> 00:12:36,497 Tim : there's an old phrase. 238 00:12:36,497 --> 00:12:37,607 You make your own luck. 239 00:12:38,007 --> 00:12:39,207 And for example, rubella. 240 00:12:39,207 --> 00:12:42,477 What you're saying is the hidden tragedy behind these 241 00:12:42,477 --> 00:12:44,037 vaccine preventable illnesses. 242 00:12:44,307 --> 00:12:49,477 Because rubella it is sort of the milder, the baby version of measles, right? 243 00:12:49,477 --> 00:12:52,087 It's like German measles, it's called, by the way, it's called German measles, 244 00:12:52,437 --> 00:12:56,837 only because it was first described by German physicians in the 18 hundreds. 245 00:12:56,837 --> 00:12:58,457 It's nothing to do with anything in particular. 246 00:12:58,737 --> 00:13:02,632 It is typically a milder course, milder course of just clinically 247 00:13:02,632 --> 00:13:03,862 they're not as miserable. 248 00:13:04,292 --> 00:13:09,222 Uh, In fact, measles comes from the old Latin miser, like miser in, you 249 00:13:09,222 --> 00:13:13,036 know, in English, miserellu, uh, is like the little miserable one. 250 00:13:13,036 --> 00:13:15,466 So measles is the little miserable one. 251 00:13:15,716 --> 00:13:18,802 Rubella is like the little reddened one the, the ruberus one. 252 00:13:19,092 --> 00:13:23,897 And I say that because , the actual disease itself in a child is often mild 253 00:13:23,897 --> 00:13:28,607 and they're okay, but it's that hidden tragedy the mother doesn't realize. 254 00:13:28,687 --> 00:13:30,697 And a blueberry muffin baby is born. 255 00:13:30,967 --> 00:13:32,677 Totally devastated, as you mentioned. 256 00:13:32,737 --> 00:13:37,817 And man, what a way to just prevent misery by these vaccines 257 00:13:37,817 --> 00:13:38,807 that prevent these illnesses. 258 00:13:39,377 --> 00:13:43,957 So, it's tough because again, you know, in the moment we are helping people 259 00:13:43,957 --> 00:13:48,217 in the emergency department and people might not realize the long game here. 260 00:13:48,277 --> 00:13:50,624 And we have that perspective. 261 00:13:50,924 --> 00:13:54,114 So we try to balance out how much counseling does 262 00:13:54,134 --> 00:13:55,394 this person need right now? 263 00:13:55,394 --> 00:13:57,314 What part of me do they need? 264 00:13:57,314 --> 00:13:59,594 Do they need my head, my heart, or my hands? 265 00:13:59,594 --> 00:14:02,044 You know, what part of myself can I help them with? 266 00:14:02,464 --> 00:14:04,174 Because again, you have to bring people along with you. 267 00:14:04,174 --> 00:14:06,994 You can't lecture them into submission. 268 00:14:06,994 --> 00:14:09,874 And you need to really win hearts and minds on this. 269 00:14:09,874 --> 00:14:13,824 And part of that is, I think being open and honest, but also 270 00:14:13,824 --> 00:14:16,944 compassionate when we see people who come in with these questions. 271 00:14:17,409 --> 00:14:17,829 Sam: Yeah. 272 00:14:18,219 --> 00:14:21,444 So difficult to do when you're trying to convince someone of 273 00:14:21,444 --> 00:14:25,604 something who completely disagrees with you but very, very important. 274 00:14:26,044 --> 00:14:26,964 Absolutely very important. 275 00:14:27,544 --> 00:14:27,634 Tim : Yeah. 276 00:14:27,694 --> 00:14:29,404 And a little story about mumps, right? 277 00:14:29,404 --> 00:14:31,654 So, you know, of course we talk about measles and we see outbreaks. 278 00:14:31,654 --> 00:14:33,034 Disneyland is not far away. 279 00:14:33,034 --> 00:14:34,504 We get Disneyland measles. 280 00:14:34,504 --> 00:14:37,964 Oftentimes, all the little kiddies have a magical connection. 281 00:14:37,964 --> 00:14:39,374 And then they give it to each other. 282 00:14:39,724 --> 00:14:42,254 The child him or herself is often okay. 283 00:14:42,254 --> 00:14:45,134 And it's more about just making sure that the person who should never 284 00:14:45,134 --> 00:14:48,414 get measles, nobody should, but the immuno immunocompromised will do okay. 285 00:14:48,744 --> 00:14:50,434 Mumps is tough. 286 00:14:50,434 --> 00:14:51,694 You mentioned the outbreaks. 287 00:14:52,394 --> 00:14:56,954 I had a, this is all very you know, I'm gonna give you just the generics of it. 288 00:14:57,114 --> 00:15:00,194 A young teenager comes in with groin pain. 289 00:15:00,464 --> 00:15:04,064 Of course, like any teenage boy doesn't tell mom about his groin 290 00:15:04,064 --> 00:15:05,654 pain 'cause it's super embarrassing. 291 00:15:05,714 --> 00:15:08,474 Oftentimes we'll see delayed torsion for that reason. 292 00:15:08,474 --> 00:15:09,744 And there's already ischemia. 293 00:15:10,324 --> 00:15:13,144 So a kid comes in and everybody's already thinking, let's do an ultrasound. 294 00:15:13,144 --> 00:15:14,284 Let's make sure it's not torsion. 295 00:15:14,984 --> 00:15:17,774 You know, the poor sheepish guy explained a little bit more. 296 00:15:17,834 --> 00:15:19,694 You realize he actually has mumps. 297 00:15:19,694 --> 00:15:23,624 The family, just, you know, it wasn't an access issue to vaccines. 298 00:15:23,624 --> 00:15:27,684 They just didn't really see the point and they just, it fell off their radar. 299 00:15:28,374 --> 00:15:33,374 So here comes this boy who has unilateral orchitis and the mother 300 00:15:33,374 --> 00:15:37,184 kind of also was feeling he'll get over this and they'll be fine. 301 00:15:37,209 --> 00:15:37,899 And she's right. 302 00:15:37,929 --> 00:15:42,519 And I, again, we talked about choosing the right amount of information or 303 00:15:42,519 --> 00:15:44,569 interaction for each presentation. 304 00:15:44,599 --> 00:15:47,569 And she kept pushing, is he gonna be okay? 305 00:15:47,569 --> 00:15:49,099 What are the long-term effects? 306 00:15:49,549 --> 00:15:53,809 And, you know, I don't want to be definitive when I'm speaking to these 307 00:15:53,809 --> 00:15:54,979 families because what do I know? 308 00:15:54,979 --> 00:15:58,459 I don't have a crystal ball and this is why longitudinal primary care is 309 00:15:58,503 --> 00:16:03,684 so important . But she's asking me in earnest, I tell her, listen, the reason 310 00:16:03,684 --> 00:16:08,014 why we worry about this is because of course you can have aseptic meningitis. 311 00:16:08,014 --> 00:16:08,884 You have encephalitis. 312 00:16:09,039 --> 00:16:12,019 I'm speaking to you in our terms, not in her vernacular. 313 00:16:12,728 --> 00:16:15,140 I said, you're worried about infertility and so am I, I'm 314 00:16:15,140 --> 00:16:16,310 worried about his sterility. 315 00:16:17,010 --> 00:16:22,500 And Sam, she went from having sort of a, red faced sort of very frustrated 316 00:16:22,500 --> 00:16:24,630 speaking about this issue to her face. 317 00:16:24,630 --> 00:16:28,160 Just kind of had this gray curtain go over her and it's landed. 318 00:16:28,160 --> 00:16:34,817 My only boy may not be able to have children and he's a young teenager 319 00:16:35,357 --> 00:16:35,437 Sam: Hmm. 320 00:16:35,447 --> 00:16:38,147 Tim : it just like was a moment and I just let her have the moment. 321 00:16:38,147 --> 00:16:39,527 I'm not gonna sit there and lecture her. 322 00:16:39,857 --> 00:16:41,747 And I tried to help her with as much as I knew. 323 00:16:41,747 --> 00:16:44,184 And then of course this conversation shouldn't end here. 324 00:16:44,184 --> 00:16:46,834 It should continue on with primary care. 325 00:16:47,534 --> 00:16:51,514 But you know, on the bright side, we only had unilateral orchitis, 326 00:16:51,534 --> 00:16:53,874 which is often a bit more favorable. 327 00:16:53,874 --> 00:16:58,034 I believe the sterility rate is gonna be about 20% or so, which is not great. 328 00:16:58,034 --> 00:17:02,310 If you have bilateral orchitis then you're looking at sterility, infertility 329 00:17:02,310 --> 00:17:04,860 rates up to, you know, 90%, 80%. 330 00:17:05,794 --> 00:17:08,644 , So the way I couched that was yes, that is always our concern. 331 00:17:08,989 --> 00:17:12,589 And yes, we'll see how this goes and, you know, let's do what we can going 332 00:17:12,589 --> 00:17:15,019 from here and helping 'em feel better. 333 00:17:15,379 --> 00:17:19,279 And then I really would encourage a larger discussion with your pediatrician, 334 00:17:19,279 --> 00:17:22,669 because I really don't want this to happen to anyone that you know or love. 335 00:17:23,089 --> 00:17:25,279 And I kind of let it be again, she had some other questions. 336 00:17:25,279 --> 00:17:25,729 I was okay. 337 00:17:25,729 --> 00:17:30,109 But you know, these poignant moments come up and I think that this kind 338 00:17:30,109 --> 00:17:33,285 of article is important for us because , forewarned is forearmed. 339 00:17:33,285 --> 00:17:37,575 If we're ready already with some of this knowledge and some talking 340 00:17:37,575 --> 00:17:40,485 points, and maybe the way that we're flushing this conversation out might 341 00:17:40,485 --> 00:17:44,165 be helpful to someone when they have that next difficult conversation. 342 00:17:44,760 --> 00:17:45,050 Sam: Yeah. 343 00:17:45,750 --> 00:17:46,755 Yeah, absolutely. 344 00:17:47,455 --> 00:17:47,815 Okay. 345 00:17:47,845 --> 00:17:50,605 Let's talk about what these things look like. 346 00:17:50,605 --> 00:17:52,495 So how about we start with measles? 347 00:17:52,545 --> 00:17:56,985 Since I think that's probably the one we're most concerned about, at least 348 00:17:56,985 --> 00:18:01,371 for its infectious abilities and for some of the outbreaks we've been seeing. 349 00:18:01,371 --> 00:18:05,885 So, when we're seeing a child and we're suspecting measles, 350 00:18:05,885 --> 00:18:07,595 what are the common symptoms? 351 00:18:07,595 --> 00:18:09,005 There's a classic description. 352 00:18:09,005 --> 00:18:10,205 Does that actually happen? 353 00:18:10,205 --> 00:18:12,485 You know, does anything classically present anymore? 354 00:18:13,185 --> 00:18:16,685 Tim : Yeah it's also hard because of course you have the three C's, the 355 00:18:16,685 --> 00:18:21,458 cough, coryza and conjunctivitis, that will be looking like pretty much 356 00:18:21,458 --> 00:18:22,648 any other cold right most of the time 357 00:18:22,803 --> 00:18:23,093 Sam: Yeah. 358 00:18:23,688 --> 00:18:26,988 Tim : And it's difficult when you see a lot of patients all at once 359 00:18:26,988 --> 00:18:29,898 and you are just trying to do the best you can for the waiting room. 360 00:18:30,168 --> 00:18:35,011 However, I would just say it is a good moment to pause and say, wow, how often 361 00:18:35,011 --> 00:18:40,262 do you really see cough conjunctivitis and coryza all at the same time? 362 00:18:40,262 --> 00:18:41,982 Oftentimes, you'll see it. 363 00:18:42,257 --> 00:18:43,457 One at a time. 364 00:18:43,457 --> 00:18:44,477 It'll evolve over time. 365 00:18:44,477 --> 00:18:46,397 This usually comes all at once. 366 00:18:47,097 --> 00:18:48,417 So what do we do with that? 367 00:18:48,657 --> 00:18:52,827 I'd say anyone who comes in looking a little bit more miserable from their 368 00:18:52,827 --> 00:18:57,297 cold, that they should, this is before the rash, cough coryza, conjunctivitis. 369 00:18:57,637 --> 00:19:00,277 you go, Hmm, lemme look inside the buccal mucosa. 370 00:19:00,837 --> 00:19:04,287 At that point though, I want you to put your mask on because 371 00:19:04,337 --> 00:19:08,417 as we know, measles is not only airborne, but it's aerosolized, 372 00:19:08,417 --> 00:19:09,497 you know, it flips in the air. 373 00:19:09,497 --> 00:19:15,177 So anyone who in any concern whatsoever, I say slap an N 95 on and just go for that. 374 00:19:15,177 --> 00:19:17,217 But let's just say you have your normal surgical mask on. 375 00:19:17,917 --> 00:19:20,097 You should look at, some specific things we can find in the 376 00:19:20,112 --> 00:19:21,897 buccal mucosa Koplik's spots. 377 00:19:22,327 --> 00:19:26,137 Henry Koplik was a pediatrician in the late 18 hundreds in New York 378 00:19:26,167 --> 00:19:27,637 who basically had a measles clinic. 379 00:19:27,637 --> 00:19:31,747 This guy noticed all of these measles outbreaks and he was the first to 380 00:19:31,747 --> 00:19:37,147 describe the bluish white, tiny little grain of salt on a slight little red 381 00:19:37,177 --> 00:19:41,057 ring that you only see before the rash. 382 00:19:41,147 --> 00:19:42,737 It goes away before the rash. 383 00:19:42,737 --> 00:19:47,997 The moment that you have is with a cough coryza conjunctivitis that comes in. 384 00:19:47,997 --> 00:19:49,167 It's so nonspecific. 385 00:19:49,377 --> 00:19:51,037 Look in that buccal mucosa. 386 00:19:51,057 --> 00:19:55,747 If you see little weird grains of salt, do not pass go. 387 00:19:55,747 --> 00:19:57,247 This child has measles. 388 00:19:57,487 --> 00:19:58,327 He has measles. 389 00:19:58,537 --> 00:20:00,397 We've known this since 1896. 390 00:20:00,397 --> 00:20:01,557 Thank you, Dr. Henry Koplik. 391 00:20:02,112 --> 00:20:03,402 We should pay attention to these things. 392 00:20:03,402 --> 00:20:07,452 And that's clinical enough because the next day or the day after will 393 00:20:07,452 --> 00:20:10,632 start a little morbilliform rash. 394 00:20:10,872 --> 00:20:14,262 It starts with a hairline, like some paint that's dumped on your head. 395 00:20:14,472 --> 00:20:18,552 And it slowly, slowly drips to your face, to your trunk, to your extremities. 396 00:20:19,252 --> 00:20:23,382 stay away from anyone who could be really hurt by measles. 397 00:20:23,412 --> 00:20:27,042 And that is our real detective work that we can do. 398 00:20:27,372 --> 00:20:32,082 Cough coryza conjunctivitis all at once in a miserable measles little one. 399 00:20:32,082 --> 00:20:37,822 Look in that buccal mucosa, and you're gonna save 12 to 18 people from 400 00:20:37,822 --> 00:20:39,742 being infected, the R nought measles. 401 00:20:40,442 --> 00:20:43,397 Sam: And those koplik spots, those are gonna go away. 402 00:20:43,397 --> 00:20:47,717 So we'll see them before the rash, but if the person already has a rash, no 403 00:20:47,717 --> 00:20:51,647 point in even looking really, because we wouldn't expect to see the Koplik's spots. 404 00:20:51,782 --> 00:20:55,082 Tim : Yeah, it's risk benefit Sam, because you do really wanna open that mouth 405 00:20:55,082 --> 00:20:56,672 that's gonna shoot measles in your face. 406 00:20:56,972 --> 00:20:59,822 So, you know, we look, when we see cough coryza conjunctivitis, 407 00:20:59,822 --> 00:21:00,982 no rash, we look for the Kopliks. 408 00:21:01,262 --> 00:21:03,212 But once the rash happens, Koplik is gone. 409 00:21:03,582 --> 00:21:06,242 And also, you know, by this isn't talked about very often, which is 410 00:21:06,242 --> 00:21:07,592 why I wanna emphasize it today. 411 00:21:08,072 --> 00:21:10,772 People will sometimes see a weird looking rash. 412 00:21:10,772 --> 00:21:11,402 They're not sure. 413 00:21:11,402 --> 00:21:13,112 They'll look in the mouth and say, there's nothing in the 414 00:21:13,112 --> 00:21:14,282 mouth, that can't be measles. 415 00:21:14,312 --> 00:21:15,212 That's not true. 416 00:21:15,512 --> 00:21:18,742 Koplik is gone by the time the rash happens. 417 00:21:19,442 --> 00:21:19,682 Sam: Okay. 418 00:21:19,682 --> 00:21:19,922 Yeah. 419 00:21:19,922 --> 00:21:22,472 So very important to keep in mind in that scenario. 420 00:21:22,472 --> 00:21:27,632 And then when we think about patients who might present to the ED with 421 00:21:27,632 --> 00:21:32,642 complications of measles, now we've got a whole host of things that can happen. 422 00:21:32,972 --> 00:21:38,955 Things like, otitis media, diarrhea, pneumonia corneal complications so 423 00:21:39,045 --> 00:21:40,918 they can have corneal involvement. 424 00:21:40,988 --> 00:21:42,818 And then immunosuppression. 425 00:21:42,818 --> 00:21:46,478 Now this is interesting as the cause for all of these issues. 426 00:21:46,668 --> 00:21:51,168 People who get measles and then recover are immunosuppressed for 427 00:21:51,168 --> 00:21:52,638 quite a period of time, right. 428 00:21:52,693 --> 00:21:53,083 Tim : That's right. 429 00:21:53,083 --> 00:21:55,093 They're immunosuppressed from anything. 430 00:21:55,093 --> 00:21:56,503 It's not just from the measles. 431 00:21:56,833 --> 00:21:59,603 So, we treat them as relatively immunocompromised. 432 00:21:59,633 --> 00:22:03,143 And that's why it's really important to get a good history for people who come in. 433 00:22:03,143 --> 00:22:06,593 Often children will come in with serial URIs, serial infections, but it's 434 00:22:06,593 --> 00:22:10,533 really important to say how has he or she been over the past several months? 435 00:22:10,903 --> 00:22:14,653 There is something that, this is actually a relatively new description, 436 00:22:14,653 --> 00:22:16,333 what's called immune amnesia. 437 00:22:16,383 --> 00:22:19,833 We've only really had this documented for about the past 10 years or 438 00:22:19,833 --> 00:22:24,840 so, and this immune amnesia that is kind of like a nuclear bomb to 439 00:22:24,840 --> 00:22:28,157 your immune system, measles, for two to three years, it can last. 440 00:22:28,277 --> 00:22:34,283 So in a young child who's susceptible and exposed to so many illnesses constantly 441 00:22:34,883 --> 00:22:37,073 that is why they'll get the pneumonia. 442 00:22:37,133 --> 00:22:38,793 That is the, the super infection. 443 00:22:39,193 --> 00:22:41,163 The encephalitis is another mechanism. 444 00:22:41,163 --> 00:22:45,207 And of course, long-term, more of a, autoimmune issue is the 445 00:22:45,207 --> 00:22:48,507 subacute sclerosing panencephalitis, which, you know, you could have 446 00:22:48,507 --> 00:22:50,877 the, totally boring measles. 447 00:22:50,877 --> 00:22:52,047 It's a little bit of a rash. 448 00:22:52,047 --> 00:22:54,027 Everyone gets upset for a week or so. 449 00:22:54,147 --> 00:22:57,477 They go about their lives three years, five years, 10 years later. 450 00:22:57,807 --> 00:22:59,337 They're neurologically devastated. 451 00:22:59,637 --> 00:23:03,237 Those hidden tragedies of these vaccine preventable 452 00:23:03,237 --> 00:23:05,572 illnesses continue to sprout up. 453 00:23:05,572 --> 00:23:08,392 So those are the things that I'll sometimes point to when 454 00:23:08,392 --> 00:23:10,522 people will be very hesitant. 455 00:23:11,222 --> 00:23:11,402 Sam: Yeah. 456 00:23:11,402 --> 00:23:15,872 And this complication, this subacute sclerosing panencephalitis, 457 00:23:15,992 --> 00:23:17,702 thankfully is, is not very common. 458 00:23:17,702 --> 00:23:19,862 This says five to 10 cases per million. 459 00:23:20,082 --> 00:23:26,732 But this is a gradually deteriorating neurological devastation that starts, 460 00:23:26,732 --> 00:23:30,812 you said, you know, anywhere from three to 10 years, even after measles 461 00:23:30,812 --> 00:23:33,212 infection and is completely untreatable. 462 00:23:33,272 --> 00:23:38,012 There's no way to stop the progression and it results in death for the child. 463 00:23:38,387 --> 00:23:40,067 Tim : Preventable, but untreatable 464 00:23:40,310 --> 00:23:41,645 Sam: that stuff just gives me the chills. 465 00:23:42,035 --> 00:23:45,235 Tim : Emergency medicine is such a humbling fulfilling you know, 466 00:23:45,295 --> 00:23:47,185 difficult path that we have chosen. 467 00:23:47,215 --> 00:23:51,278 We see people at their worst and sometimes they can rise to the occasion 468 00:23:51,278 --> 00:23:54,548 and be at their best, but we have to also rise to the occasion, be at our 469 00:23:54,548 --> 00:23:56,378 best and give them what they need. 470 00:23:56,378 --> 00:23:58,658 And if that's information, if that's reassurance, if that's 471 00:23:59,078 --> 00:24:00,818 guidance that's what we try to do. 472 00:24:01,518 --> 00:24:01,808 Sam: Yeah. 473 00:24:02,508 --> 00:24:02,798 Okay. 474 00:24:02,843 --> 00:24:07,913 So measles, cough, coryza, conjunctivitis, fever, malaise, maybe not eating well. 475 00:24:08,243 --> 00:24:11,273 Koplik spots that are gonna be there a couple of days. 476 00:24:11,433 --> 00:24:12,273 And then gone. 477 00:24:12,333 --> 00:24:16,503 And then the onset of rash with maybe some lymphadenopathy, and then all of 478 00:24:16,503 --> 00:24:18,153 those complications we just talked about. 479 00:24:18,363 --> 00:24:18,813 Tim : That's right. 480 00:24:18,813 --> 00:24:21,243 And for measles speaking to the family, of course, you know, you're 481 00:24:21,243 --> 00:24:24,813 infectious, four days before the rash and then four days after the rash. 482 00:24:24,813 --> 00:24:26,753 So it's not a get outta jail free card. 483 00:24:26,753 --> 00:24:29,213 This child needs to be isolated, and this is why it's important 484 00:24:29,213 --> 00:24:31,673 to get public health involved, because they will make phone checks. 485 00:24:31,673 --> 00:24:33,833 They will continue to counsel people. 486 00:24:34,013 --> 00:24:36,713 How many times have people forgotten what we tell them in the emergency department? 487 00:24:36,713 --> 00:24:39,923 We try to write everything down, but that reinforcement later on with 488 00:24:39,923 --> 00:24:42,263 the public, the wonderful public health nurses that are out there to 489 00:24:42,263 --> 00:24:44,513 help us to keep our system running. 490 00:24:45,213 --> 00:24:45,453 Sam: Okay. 491 00:24:45,453 --> 00:24:46,683 And then mumps. 492 00:24:46,743 --> 00:24:50,433 So, you know, we always think about the parotid gland swelling in the kid with 493 00:24:50,433 --> 00:24:53,013 the classic swollen jaw on both sides. 494 00:24:53,013 --> 00:24:57,843 But mumps really is going to infect any glandular organ in this scenario. 495 00:24:57,843 --> 00:25:00,863 So they're going to get problems with pancreas. 496 00:25:00,893 --> 00:25:03,383 They're gonna get problems with their reproductive organs. 497 00:25:03,383 --> 00:25:06,653 They're gonna get problems with really , any gland in the body. 498 00:25:06,813 --> 00:25:10,903 And it doesn't have to be just the jaw , but that may be the one symptom 499 00:25:10,903 --> 00:25:13,603 that brings them to the emergency department that makes us think about it. 500 00:25:13,863 --> 00:25:16,423 But you already mentioned like testicular pain or in a 501 00:25:16,423 --> 00:25:18,013 female might be abdominal pain 502 00:25:18,023 --> 00:25:20,733 Tim : You know, it can be surprising, and I'm glad you brought that up, 503 00:25:20,733 --> 00:25:24,473 because again, mumps loves lacy tissue. 504 00:25:24,563 --> 00:25:28,927 Anything that has that lacy glandular look to it from a histology standpoint. 505 00:25:29,327 --> 00:25:31,727 So we should be aware that it can present in different ways. 506 00:25:31,727 --> 00:25:34,453 The, case that I mentioned of this young teenager, he really didn't 507 00:25:34,453 --> 00:25:35,533 have a lot of facial swelling. 508 00:25:35,563 --> 00:25:37,453 You know, his habitus was a little bit larger, and so it 509 00:25:37,453 --> 00:25:38,713 didn't really look much bigger. 510 00:25:38,713 --> 00:25:40,303 His face didn't seem much fuller. 511 00:25:40,303 --> 00:25:42,943 It was just unilateral swelling. 512 00:25:42,943 --> 00:25:47,113 And his doppler was normal and it really, on exam, you could 513 00:25:47,113 --> 00:25:48,793 tell that this was a bit swollen. 514 00:25:48,943 --> 00:25:51,893 But, difficult because mumps, of course, you know, I love 515 00:25:51,953 --> 00:25:53,303 etymology of words, as you can see. 516 00:25:53,303 --> 00:25:58,833 And mumps comes from the old English of a grimace, pouty face is to mump. 517 00:25:58,833 --> 00:25:59,643 Is to pout. 518 00:25:59,883 --> 00:26:01,803 So we kind of think of someone as just like, you know, sour 519 00:26:01,803 --> 00:26:03,693 face, their jaw line is down. 520 00:26:04,033 --> 00:26:05,743 That's what we think of for mumps. 521 00:26:06,163 --> 00:26:08,323 But man, we should be careful, right? 522 00:26:08,323 --> 00:26:09,023 Is it orchitis? 523 00:26:09,043 --> 00:26:09,833 Is it oophoritis? 524 00:26:09,853 --> 00:26:10,633 Is it mastitis? 525 00:26:10,633 --> 00:26:11,623 Is it pancreatitis? 526 00:26:11,953 --> 00:26:16,853 Or this kid who's now seeming a little bit weird, why are you so weird? 527 00:26:16,853 --> 00:26:18,843 Sir? Your utox is normal. 528 00:26:19,113 --> 00:26:19,743 No trauma. 529 00:26:20,133 --> 00:26:24,383 Oh no, you have aseptic meningitis because you have your mumps. 530 00:26:24,403 --> 00:26:27,790 So, we keep our differential broad for that reason. 531 00:26:28,490 --> 00:26:31,720 Sam: And then, equally catastrophic with the central nervous system 532 00:26:31,720 --> 00:26:37,400 encephalitis and hearing loss myocarditis nephritis, multiple 533 00:26:37,460 --> 00:26:39,170 other complications that can occur. 534 00:26:39,470 --> 00:26:43,430 About a third of these cases of mumps are asymptomatic, but these people are 535 00:26:43,430 --> 00:26:47,870 still contagious, so still out there passing it along to everyone else. 536 00:26:47,870 --> 00:26:51,560 And so contact tracing may not be a perfect science in 537 00:26:51,560 --> 00:26:52,850 this particular scenario. 538 00:26:53,465 --> 00:26:53,615 Tim : Yeah. 539 00:26:53,705 --> 00:26:55,805 You know, measles is very pathognomonic. 540 00:26:55,835 --> 00:27:00,007 Mumps should be, but I, find that a lot of public health officials push 541 00:27:00,007 --> 00:27:02,037 more for confirmatory testing in mumps. 542 00:27:02,037 --> 00:27:06,887 So they'll ask for the PCR for the buccal mucosa, or even like an IGM serology. 543 00:27:07,247 --> 00:27:09,437 I think also because, you know, orchitis of course can 544 00:27:09,437 --> 00:27:11,057 be various infectious diseases, 545 00:27:11,307 --> 00:27:11,597 Sam: Yeah. 546 00:27:11,697 --> 00:27:15,637 Tim : From a public health standpoint, the agency is dealing with people 547 00:27:15,637 --> 00:27:17,517 with varied degrees of experience. 548 00:27:17,817 --> 00:27:22,247 And so they wanna make sure that our sensitivity and specificity is optimized. 549 00:27:22,427 --> 00:27:24,407 So that's why we say, Hmm, is it really mumps? 550 00:27:24,407 --> 00:27:27,587 And that's why they will tend to ask you for more testing. 551 00:27:27,937 --> 00:27:29,617 And it is, you know, supportive care. 552 00:27:30,317 --> 00:27:34,291 So it's not as infectious as the others but it's still something 553 00:27:34,391 --> 00:27:35,861 that we need to pay attention to. 554 00:27:36,382 --> 00:27:38,452 Sam: all right, let's move on to rubella. 555 00:27:38,452 --> 00:27:42,682 So in this case, much like mumps, a large percentage up to 50% can 556 00:27:42,682 --> 00:27:46,642 be asymptomatic, which again, is problematic for transmission. 557 00:27:46,902 --> 00:27:52,212 But these in children are gonna present with fever, headache, cough, 558 00:27:52,212 --> 00:27:54,192 congestion, sounds a lot like measles, 559 00:27:54,252 --> 00:27:54,672 Tim : Mm-hmm. 560 00:27:54,822 --> 00:27:55,782 Sam: and a rash. 561 00:27:55,942 --> 00:28:00,506 And then this is also gonna have this prodrome for one to five days 562 00:28:00,506 --> 00:28:02,426 before the rash appears right. 563 00:28:02,591 --> 00:28:03,131 Tim : Yes. 564 00:28:03,131 --> 00:28:05,951 And you know, that's why Rubella is the little red. 565 00:28:05,951 --> 00:28:08,571 From a clinical standpoint, it is much milder. 566 00:28:08,621 --> 00:28:11,051 It's sort of the baby version of measles. 567 00:28:11,711 --> 00:28:15,461 and there may be cases where we call it measles, but it ends up 568 00:28:15,461 --> 00:28:18,131 being rubella and we just never got the confirmatory testing. 569 00:28:18,131 --> 00:28:21,191 But it's my understanding that we don't have a lot of cases of 570 00:28:21,191 --> 00:28:22,406 rubella, at least in this country. 571 00:28:23,106 --> 00:28:28,206 You know, I'm okay over calling it, but rubella often comes with this red rash 572 00:28:28,546 --> 00:28:32,926 there's often arthralgias and they're just not as miserable as, our little 573 00:28:32,926 --> 00:28:34,686 miserable measles in children are. 574 00:28:35,166 --> 00:28:37,416 Having said that though, as you mentioned, the sensory neural 575 00:28:37,416 --> 00:28:41,639 deafness can be devastating and then devastating to a fetus who is 576 00:28:41,799 --> 00:28:43,589 exposed to this infectious disease 577 00:28:44,441 --> 00:28:48,176 . Sam: And now the risk to a fetus here is probably, I think, the 578 00:28:48,176 --> 00:28:49,766 highest of all of these diseases. 579 00:28:49,766 --> 00:28:54,176 It says approximately 85% of fetuses exposed to rubella in 580 00:28:54,176 --> 00:28:57,146 the first trimester are gonna develop some kind of birth defect. 581 00:28:57,491 --> 00:28:57,641 Tim : Yeah. 582 00:28:57,701 --> 00:28:58,851 And that's just not acceptable. 583 00:28:58,851 --> 00:28:59,001 Right. 584 00:28:59,001 --> 00:29:00,441 An 85% risk. 585 00:29:00,831 --> 00:29:05,211 I mean, that's a no go of all the things we worry about in prenatal care. 586 00:29:05,421 --> 00:29:09,041 People are so, assiduous about taking prenatal vitamins every day. 587 00:29:09,101 --> 00:29:09,671 I love it. 588 00:29:09,671 --> 00:29:10,165 So good. 589 00:29:10,375 --> 00:29:10,992 But Wow. 590 00:29:11,232 --> 00:29:13,002 You know, you're a little bit low on the iron. 591 00:29:13,002 --> 00:29:16,692 We can get over that, but not so much on the rubella. 592 00:29:16,962 --> 00:29:17,512 Sam: The rubella. 593 00:29:17,532 --> 00:29:17,892 Yeah. 594 00:29:18,592 --> 00:29:24,112 And mother's immunity is safeguarding for the fetus in this sense. 595 00:29:24,112 --> 00:29:27,862 So as long as mom is vaccinated, that passes to the fetus. 596 00:29:28,132 --> 00:29:28,582 Tim : yes. 597 00:29:28,942 --> 00:29:31,042 Sam: Okay, so let's talk about varicella chickenpox. 598 00:29:31,042 --> 00:29:34,862 Probably the one I'm for sure certain I have seen and had 599 00:29:35,012 --> 00:29:38,162 actually as a child, I guess I'm old enough to have experienced it. 600 00:29:38,732 --> 00:29:42,142 So this is another rash, right? 601 00:29:42,142 --> 00:29:44,482 This one happens to be very itchy, right? 602 00:29:44,482 --> 00:29:48,992 So fever itchy rash has those little vesicles that appear 603 00:29:49,152 --> 00:29:53,592 multiple stages of ages because the rash comes in these waves. 604 00:29:53,862 --> 00:29:56,532 And equally miserable. 605 00:29:56,702 --> 00:30:00,702 But thankfully, actually probably , the one of these that actually 606 00:30:00,702 --> 00:30:02,232 has some treatment options, right? 607 00:30:02,757 --> 00:30:03,657 Tim : Yeah, , that's exactly right. 608 00:30:03,677 --> 00:30:08,247 You know, varus in Latin is a pimple, so varicella is like little 609 00:30:08,247 --> 00:30:09,537 pimples, little pimple disease. 610 00:30:09,837 --> 00:30:12,327 So all these little, you know, pimple diseases are all over you. 611 00:30:12,327 --> 00:30:15,237 And , I'm gonna just expose my own bias too, because again, 612 00:30:15,237 --> 00:30:18,567 like when we were little, you know, everybody gets chickenpox. 613 00:30:18,567 --> 00:30:19,947 There were chickenpox parties. 614 00:30:20,067 --> 00:30:20,517 Sam: Yeah. 615 00:30:20,727 --> 00:30:22,047 Tim : Get it all over with everyone. 616 00:30:22,167 --> 00:30:24,567 And I think we took a little bit of a laissez-faire approach. 617 00:30:24,567 --> 00:30:27,347 , And I think that we're all probably pretty lucky for that. 618 00:30:27,777 --> 00:30:32,127 The problem is though, of course we have an effective vaccine that 619 00:30:32,127 --> 00:30:35,877 can really decrease morbidity and sometimes mortality. 620 00:30:35,877 --> 00:30:39,297 You know, varicella is often okay, but not in the wrong person. 621 00:30:39,297 --> 00:30:42,927 And the person who can't get vaccines, immunocompromised, the chemotherapy 622 00:30:42,927 --> 00:30:47,487 patients, what have you, we're really doing a service to ourselves as 623 00:30:47,487 --> 00:30:50,961 well as our community by becoming vaccinated . But anyway, my bias 624 00:30:50,961 --> 00:30:52,341 is like, it's just chickenpox. 625 00:30:52,371 --> 00:30:52,911 It'll be okay. 626 00:30:53,121 --> 00:30:57,261 So I have to remind myself, no, it's not, we really do have to be careful about 627 00:30:57,261 --> 00:31:03,261 once we've diagnosed it to isolate because it is like all of , the things that 628 00:31:03,261 --> 00:31:04,666 we're talking about, , it is airborne. 629 00:31:04,666 --> 00:31:08,919 It's airborne and droplet and it's extremely infectious , and preventable. 630 00:31:09,619 --> 00:31:12,674 Sam: And much like the other viruses we just talked about, you 631 00:31:12,674 --> 00:31:16,304 get symptoms for a couple of days before the rash appears, and then 632 00:31:16,304 --> 00:31:18,374 the rash scabs over in about a week. 633 00:31:18,374 --> 00:31:21,854 And at that point, you're finally no longer infectious when you don't 634 00:31:21,854 --> 00:31:25,514 have any more vesicles that can rupture and release the fluid right. 635 00:31:25,587 --> 00:31:26,457 Tim : That's exactly right. 636 00:31:26,547 --> 00:31:29,937 And then just kind of again, putting on our emergency medicine hat. 637 00:31:29,937 --> 00:31:33,987 You know, here we are as clinicians who are trying to make sure that 638 00:31:33,987 --> 00:31:35,367 everyone is safe in the department. 639 00:31:35,557 --> 00:31:37,747 Oftentimes the nurses will call me and say, Hey, this is rash. 640 00:31:37,747 --> 00:31:39,307 Can you please see this person in triage? 641 00:31:39,367 --> 00:31:43,457 I'll run over there verify that it may or may not be measles, 642 00:31:43,457 --> 00:31:44,442 varicella, what have you. 643 00:31:44,477 --> 00:31:49,131 If it is in any way, potentially chicken pox I will say okay any of the 644 00:31:49,131 --> 00:31:53,731 nurses that are in any possibility of becoming pregnant now or soon, get out 645 00:31:53,731 --> 00:31:57,731 of here, I will keep them away from that patient and I'll make sure that we 646 00:31:57,761 --> 00:31:59,471 have the right staff, for that patient. 647 00:31:59,471 --> 00:32:02,561 And I say that, and it sounds kind of like, you know, literally chicken 648 00:32:02,561 --> 00:32:07,532 little falling from the sky, but wow, what an easy thing to do often. 649 00:32:07,812 --> 00:32:09,612 And if I just need to see the patient myself, I will. 650 00:32:09,612 --> 00:32:12,372 Because often there's not a lot of nursing intervention to be done. 651 00:32:12,372 --> 00:32:13,602 I can take my own vital signs. 652 00:32:13,917 --> 00:32:14,207 Sam: Yeah. 653 00:32:14,532 --> 00:32:17,142 Tim : but it's something simple that we can do to really help people. 654 00:32:17,142 --> 00:32:21,732 And that's, that's how serious these things are because it's not just, chances 655 00:32:21,732 --> 00:32:25,512 are in emergency medicine, we often don't deal with, chances are we just say, 656 00:32:25,512 --> 00:32:30,277 listen, whether or not you, you know, we don't think about necessarily population 657 00:32:30,277 --> 00:32:32,047 probabilities, like how likely it is? 658 00:32:32,047 --> 00:32:34,567 Does this person have whatever we go, there's a possibility. 659 00:32:34,657 --> 00:32:35,647 I need to look into it. 660 00:32:36,067 --> 00:32:40,057 So we really deal with this sort of catastrophic mindset because 661 00:32:40,057 --> 00:32:41,301 that's what society needs from us. 662 00:32:41,331 --> 00:32:44,779 So I Want to have that same mindset for our own staff to keep them safe. 663 00:32:44,879 --> 00:32:46,916 Any possibility of chickenpox? 664 00:32:46,916 --> 00:32:51,386 Let's keep away the nurses, clinicians, anyone around the 665 00:32:51,386 --> 00:32:53,513 techs that are of childbearing age. 666 00:32:53,703 --> 00:32:55,789 Let's get 'em away from Potential chicken pox. 667 00:32:56,404 --> 00:32:59,284 Sam: And do you do that even if they've been vaccinated and they're pregnant? 668 00:32:59,984 --> 00:33:03,628 Tim : You know, I'm just, I'm a little bit overprotective maybe, but yes. 669 00:33:03,628 --> 00:33:04,974 cause you Know who Cares, right? 670 00:33:04,974 --> 00:33:08,204 These people are often fine and it's something that I can do. 671 00:33:08,954 --> 00:33:10,194 gonna be a good bro to everyone. 672 00:33:10,424 --> 00:33:10,964 That's what I'm gonna do. 673 00:33:11,384 --> 00:33:11,714 Sam: I like it. 674 00:33:11,924 --> 00:33:12,254 I like it. 675 00:33:12,954 --> 00:33:15,424 And you know, speaking of the possibilities. 676 00:33:15,424 --> 00:33:20,674 I thought that the appendix in this article, pages 16 and 17 lists like 677 00:33:20,764 --> 00:33:25,474 this is, I think 26 different conditions that can cause fever and rash. 678 00:33:25,504 --> 00:33:29,554 So if you're listening, we're not trying to oversimplify this. 679 00:33:29,554 --> 00:33:33,364 , There's multiple diseases that we previously had excellent vaccine 680 00:33:33,364 --> 00:33:36,284 coverage for, that were on the list, but you didn't really have 681 00:33:36,284 --> 00:33:37,634 to put near the top of the list. 682 00:33:37,634 --> 00:33:41,414 But now we've got 26 different things that can cause fever and 683 00:33:41,414 --> 00:33:43,094 rash and we're adding to it. 684 00:33:43,124 --> 00:33:47,264 The three or four things that we previously could kind of go, eh, you 685 00:33:47,264 --> 00:33:50,084 know, they're vaccinated, not worried about it, or everybody's vaccinated, 686 00:33:50,084 --> 00:33:51,464 I'm not so worried about this anymore. 687 00:33:51,784 --> 00:33:52,004 Tim : Yes. 688 00:33:52,499 --> 00:33:52,829 Wow. 689 00:33:52,959 --> 00:33:54,549 What a humbling reframe. 690 00:33:54,954 --> 00:33:55,374 Right. 691 00:33:55,654 --> 00:33:58,684 And that's why again, this discussion and this article is so important to 692 00:33:58,774 --> 00:34:01,054 refresh our minds about what to look for. 693 00:34:01,104 --> 00:34:04,219 , And this sort of speaks a little bit about the difference between inductive 694 00:34:04,219 --> 00:34:06,409 and deductive reasoning that we have in the emergency department, right? 695 00:34:06,649 --> 00:34:09,439 Deductive reasoning will often say, Hey, there's a fever and a rash. 696 00:34:09,439 --> 00:34:11,089 What are the 100 things that can cause it? 697 00:34:11,089 --> 00:34:13,549 And I'm gonna narrow it down with my history and physical to 10 things, 698 00:34:13,549 --> 00:34:16,729 and maybe I spend some time with them, or, or intervene or test. 699 00:34:16,939 --> 00:34:19,909 And I've narrowed it down to the deductive one answer. 700 00:34:20,029 --> 00:34:20,719 This is what we try to do. 701 00:34:20,749 --> 00:34:22,589 This is when we, admit people to internal medicine so that 702 00:34:22,589 --> 00:34:23,879 they have multiple days, right? 703 00:34:24,189 --> 00:34:25,359 Or pediatrics or what have you. 704 00:34:25,539 --> 00:34:28,449 So, we are trying to find for deductive reason the answer. 705 00:34:28,479 --> 00:34:28,869 That's it. 706 00:34:28,869 --> 00:34:29,589 There's only one answer. 707 00:34:30,019 --> 00:34:32,299 We often, in immersive medicine have inductive reasoning, right? 708 00:34:32,299 --> 00:34:34,669 Where we say, there's certain things that I am responsible for. 709 00:34:34,669 --> 00:34:37,299 I'm responsible to make sure this is not measles, mumps, rubella , it's 710 00:34:37,299 --> 00:34:40,359 really important that this person with chest pain doesn't have a PE aortic 711 00:34:40,539 --> 00:34:41,889 dissection and a stemi, et cetera. 712 00:34:42,249 --> 00:34:44,919 How likely are any of those things just given the chances 713 00:34:44,919 --> 00:34:45,879 you're gonna throw some dice? 714 00:34:45,879 --> 00:34:49,309 , they're not likely, they're o ur responsibility. 715 00:34:49,309 --> 00:34:52,099 So we're using inductive reasoning, the sort of sharpshooter reasoning 716 00:34:52,099 --> 00:34:55,289 of you send someone to a cardiologist and what are they gonna do? 717 00:34:55,289 --> 00:34:57,149 They're gonna do an EKG and they're gonna ask about chest pain. 718 00:34:57,449 --> 00:35:00,479 But maybe this is costochondritis, it's the cardiologist's job 719 00:35:00,479 --> 00:35:01,259 to think about the heart. 720 00:35:01,319 --> 00:35:05,339 It's the emergency medicine physician or clinician's job to think about the 721 00:35:05,339 --> 00:35:07,019 dangerous things, inductive reasoning. 722 00:35:07,229 --> 00:35:08,369 And that's why it's just sort of weird. 723 00:35:08,369 --> 00:35:09,859 You see , this long list, you go, oh my gosh. 724 00:35:09,859 --> 00:35:10,339 All these things. 725 00:35:11,039 --> 00:35:14,239 Yes, that is already pre-programmed into your mind as a clinician. 726 00:35:14,239 --> 00:35:19,239 this discussion is more about how do I use my inductive reasoning when it counts? 727 00:35:19,419 --> 00:35:21,729 Oh no, there's something that's weird about this. 728 00:35:22,059 --> 00:35:27,069 I need to explicitly make myself stop and think about measles, 729 00:35:27,099 --> 00:35:28,929 mumps rubella and varicella. 730 00:35:29,629 --> 00:35:31,759 Oh, there no, doesn't, doesn't match any of those. 731 00:35:31,759 --> 00:35:32,569 Great move on. 732 00:35:33,169 --> 00:35:37,726 But this is why , that's important for us to hyperfocus sometimes and then relax 733 00:35:37,726 --> 00:35:40,156 back when we haven't found any red flags. 734 00:35:40,856 --> 00:35:43,976 Sam: Yeah, and I thought the author did a particularly good job of 735 00:35:43,976 --> 00:35:49,296 reminding us that none of these diseases are supposed to cause purpura. 736 00:35:49,586 --> 00:35:54,366 So if you see a purpuric rash, then, even if you're in the midst of one of 737 00:35:54,366 --> 00:36:00,126 these massive measles outbreaks, stop and reframe and make sure you're not looking 738 00:36:00,126 --> 00:36:04,156 at somebody whose sepsis has you know, meningococcemia or something of that 739 00:36:04,156 --> 00:36:07,016 sort as a cause for underlying sepsis. 740 00:36:07,021 --> 00:36:11,281 , The purpuric rash is not a normal complication of any one of these diseases. 741 00:36:11,611 --> 00:36:12,571 Tim : Touch your patients. 742 00:36:12,571 --> 00:36:13,691 Look for capillary refill. 743 00:36:14,171 --> 00:36:16,661 look for blanching of those petechia and purpura. 744 00:36:16,936 --> 00:36:19,236 Put gloves on 'cause you know no one likes meningococcemia. 745 00:36:19,726 --> 00:36:20,566 Sam: Yes, yes. 746 00:36:20,566 --> 00:36:21,466 Please put gloves on. 747 00:36:22,006 --> 00:36:22,276 Okay. 748 00:36:22,276 --> 00:36:24,233 Let's talk about our pre-hospital colleagues. 749 00:36:24,233 --> 00:36:28,523 So, there are some who listen and appropriately are concerned about 750 00:36:28,523 --> 00:36:30,233 themselves and their patients. 751 00:36:30,233 --> 00:36:35,813 And so if you are an EMS colleague and you are now transporting a child 752 00:36:35,813 --> 00:36:41,093 with fever and a rash or, you know, maybe not tolerating this URI very 753 00:36:41,093 --> 00:36:43,833 well and seems to be a little bit more distressed than usual, and you happen 754 00:36:43,833 --> 00:36:47,523 to notice a rash, what are some of the things they need to keep in mind? 755 00:36:47,553 --> 00:36:51,323 Tim : Yeah, , our watchers on the wall, our front line, and these guys 756 00:36:51,323 --> 00:36:54,233 have to go into crazy environments. 757 00:36:54,413 --> 00:36:56,483 People are upset, there's bad lighting. 758 00:36:56,513 --> 00:36:57,593 No one knows anything. 759 00:36:57,713 --> 00:37:00,983 They get 'em into the rig and they turn on the lights and go, oh, no, I 760 00:37:00,983 --> 00:37:02,603 just see something I'm worried about. 761 00:37:02,963 --> 00:37:06,303 So, this is a good example of our continuing this conversation with our 762 00:37:06,303 --> 00:37:10,629 EMS colleagues and just, taking 'em aside after they bring a patient in 763 00:37:10,629 --> 00:37:12,039 and saying, Hey, how was it for you? 764 00:37:12,429 --> 00:37:14,199 And giving 'em that little kind of tidbit. 765 00:37:14,199 --> 00:37:17,169 If they're in any way concerned or we are concerned, we should communicate to them. 766 00:37:17,199 --> 00:37:20,439 And that, in fact, I would push it even further to say that we should 767 00:37:20,719 --> 00:37:22,219 make sure that their medical director. 768 00:37:22,219 --> 00:37:26,579 And the EMS agency they came from knows about this because public health takes a 769 00:37:26,579 --> 00:37:28,829 few days to track people down who go home. 770 00:37:29,159 --> 00:37:34,589 But I want that medic to know that he maybe needs to be isolated because he 771 00:37:34,589 --> 00:37:36,929 was just exposed to measles or not. 772 00:37:36,929 --> 00:37:39,569 Or I just say, Hey, have you been vaccinated for measles? 773 00:37:39,569 --> 00:37:41,009 And if he is, we'll wait and see. 774 00:37:41,399 --> 00:37:43,664 But if he hasn't been, because there are some people, as you 775 00:37:43,664 --> 00:37:45,659 know, Sam, who can't be vaccinated. 776 00:37:46,369 --> 00:37:48,229 Or the vaccine doesn't take to them. 777 00:37:48,544 --> 00:37:50,254 Those are the people I worry about even more. 778 00:37:50,494 --> 00:37:55,124 And those are the people also can get the the post-exposure prophylaxis vaccine. 779 00:37:55,474 --> 00:38:01,354 so, just kind of to answer your question though more broadly is that I think the 780 00:38:01,354 --> 00:38:05,514 most important thing is that we just cultivate those relationships with the 781 00:38:05,514 --> 00:38:07,494 medics that we see on a regular basis. 782 00:38:07,524 --> 00:38:10,314 So they feel comfortable asking us, and we feel comfortable to say, Hey, 783 00:38:10,404 --> 00:38:14,254 by the way, you know, gimme your number, gimme your supervisor's number. 784 00:38:14,674 --> 00:38:18,034 I'm gonna check in with you because if I'm worried enough that this case is 785 00:38:18,064 --> 00:38:23,374 a morbilliform rash that is now to the chest, it was at the face yesterday 786 00:38:23,744 --> 00:38:27,074 I'm gonna call you later on with our final thoughts or stick around. 787 00:38:27,074 --> 00:38:28,564 Let's make a decision right now. 788 00:38:29,304 --> 00:38:31,371 Other things they could think about, of course is just this is a good 789 00:38:31,371 --> 00:38:35,111 opportunity if you are interested in jumping into being more involved 790 00:38:35,111 --> 00:38:36,611 with pre-hospital education. 791 00:38:36,941 --> 00:38:41,501 I'd say as a community clinician, jump in, talk to the EMS agency. 792 00:38:41,621 --> 00:38:43,301 Hey, can I give my little CME? 793 00:38:44,298 --> 00:38:46,778 again, that, ongoing relationship I think is more important. 794 00:38:46,808 --> 00:38:49,658 'cause in the hustle and bustle of what we do, you may forget, oh my 795 00:38:49,658 --> 00:38:50,741 gosh, they, they're already gone. 796 00:38:51,371 --> 00:38:52,411 oh no, this kid has measles. 797 00:38:52,431 --> 00:38:53,811 And then you've missed that opportunity. 798 00:38:54,161 --> 00:38:57,021 But if you have that relationship with people, they're much more likely 799 00:38:57,021 --> 00:39:01,701 to recontact you, you recontact them and have us be a cohesive spectrum. 800 00:39:01,701 --> 00:39:06,501 'cause EMS care to emergency care, to hospital care, to even outpatient 801 00:39:06,501 --> 00:39:09,321 care, is all a long spectrum. 802 00:39:09,591 --> 00:39:11,601 And we should all be as unified as possible. 803 00:39:12,021 --> 00:39:12,321 Sam: Yeah. 804 00:39:13,021 --> 00:39:18,061 And if you are an EMS person and you know, in advance you're going in 805 00:39:18,061 --> 00:39:23,131 to pick up a child with fever and a rash, then, you know, a PPE an N95 is 806 00:39:23,131 --> 00:39:26,251 probably called for until you know for sure what it is you're dealing with. 807 00:39:26,641 --> 00:39:29,941 And then decontaminating the rig afterwards. 808 00:39:29,941 --> 00:39:33,331 So you've gotten the patient out, now you have to decontaminate everything. 809 00:39:33,611 --> 00:39:38,081 The viruses can live on surfaces for a short while, so you've gotta be 810 00:39:38,141 --> 00:39:41,411 really good about cleaning all of those surfaces, especially if they were 811 00:39:41,411 --> 00:39:43,151 coughing in the back of your ambulance. 812 00:39:43,481 --> 00:39:45,911 And then having that good handoff. 813 00:39:46,484 --> 00:39:51,224 I always like to get a direct report from paramedics, but it's not always practical. 814 00:39:51,224 --> 00:39:54,744 Sometimes it does come through nursing channels but if at all possible 815 00:39:54,744 --> 00:39:57,554 sticking around the extra couple of minutes to just make sure that the 816 00:39:57,554 --> 00:40:00,704 physician has the same report, so nothing slips through the cracks. 817 00:40:00,854 --> 00:40:01,814 I've found always to be helpful. 818 00:40:02,084 --> 00:40:04,244 Tim : and just hearing what you're saying too, Sam, makes me think of 819 00:40:04,544 --> 00:40:07,634 how many times have you been in a case where, you know, we don't have a room 820 00:40:07,634 --> 00:40:11,834 and the poor medics are hugging a wall for, you know, 20, 30 minute longer. 821 00:40:11,834 --> 00:40:12,134 Right. 822 00:40:12,614 --> 00:40:14,444 And somebody's coughing in there. 823 00:40:14,444 --> 00:40:15,324 Look, they have a rash. 824 00:40:15,374 --> 00:40:18,591 It's important for us to just say, listen, maybe this is an issue. 825 00:40:18,591 --> 00:40:19,851 And put a mask on everybody. 826 00:40:20,301 --> 00:40:21,321 Put a mask on everybody. 827 00:40:21,321 --> 00:40:21,771 And. 828 00:40:22,121 --> 00:40:26,828 I love what you say about decontaminating the rig because of all of these, you 829 00:40:26,828 --> 00:40:28,568 know, measles is the airborne one. 830 00:40:28,568 --> 00:40:31,478 It will be suspended in the air for long periods of time. 831 00:40:31,478 --> 00:40:34,814 And I would say that, I mean, I'm not an expert at this, but I would say that that 832 00:40:34,814 --> 00:40:38,834 particular vehicle should probably be outta commission until they've completely 833 00:40:38,914 --> 00:40:41,328 decontaminated the should be wide open. 834 00:40:41,398 --> 00:40:43,354 It should be terminally cleaned. 835 00:40:43,624 --> 00:40:43,941 Sam: Yeah. 836 00:40:43,981 --> 00:40:46,071 Tim : But it also goes to the fact where people are always worried 837 00:40:46,071 --> 00:40:47,421 about, well, what's aerosol? 838 00:40:47,811 --> 00:40:48,831 What's airborne? 839 00:40:48,831 --> 00:40:50,781 What's respiratory droplets, what's contact? 840 00:40:51,171 --> 00:40:51,951 It's so confusing. 841 00:40:51,951 --> 00:40:55,791 It doesn't do us any service to try to be so specific. 842 00:40:55,941 --> 00:41:00,371 But just broad strokes, when we talk about aerosol, we're talking about 843 00:41:00,401 --> 00:41:04,391 these little tiny fine particulates that float in the air measles, when 844 00:41:04,391 --> 00:41:06,131 we talk about respiratory droplets. 845 00:41:06,554 --> 00:41:10,514 They, you know, are spittle that just like flies on people's faces in their eyes. 846 00:41:10,844 --> 00:41:13,124 Those are larger molecules, and that's where we're talking 847 00:41:13,124 --> 00:41:14,174 about mumps and rubella. 848 00:41:14,504 --> 00:41:18,614 And then varicella can be both aerosol and droplet. 849 00:41:18,944 --> 00:41:23,154 You know, when you're in a rig in front of someone's face, in their home as a 850 00:41:23,154 --> 00:41:26,874 medic or in the emergency department, one of us comes in and sees people, 851 00:41:27,034 --> 00:41:30,514 there's no magical curtain that's gonna stop people from being airborne versus 852 00:41:30,514 --> 00:41:32,194 respiratory droplet versus contact. 853 00:41:32,464 --> 00:41:36,544 We should just treat all of these as potential airborne until we can peel back. 854 00:41:36,544 --> 00:41:38,194 And so that's an N95. 855 00:41:38,404 --> 00:41:40,504 And that's maybe even wearing a face shield too 856 00:41:40,704 --> 00:41:40,994 Sam: Yeah. 857 00:41:41,214 --> 00:41:42,204 Tim : for the high risk cases. 858 00:41:42,204 --> 00:41:46,449 I'm not advocating going into every patient room with that get up, but I don't 859 00:41:46,449 --> 00:41:50,979 like to try to split hairs and say, what's a respiratory droplet and what's aerosol? 860 00:41:50,979 --> 00:41:54,579 You know what, when you're that close to someone's face, it's all aerosol. 861 00:41:55,083 --> 00:41:58,593 And then you can kind of take a moment once you've made your diagnoses 862 00:41:58,593 --> 00:42:00,933 and you can then counsel people. 863 00:42:00,933 --> 00:42:03,363 You can just, you can say, okay, well, you're infectious. 864 00:42:03,363 --> 00:42:04,473 You're not as infectious. 865 00:42:04,503 --> 00:42:04,833 Here. 866 00:42:04,833 --> 00:42:05,793 You wear a surgical mask. 867 00:42:05,853 --> 00:42:07,506 You wear an n95 you go home. 868 00:42:07,716 --> 00:42:10,566 You need to stay, but you need to stay in a negative pressure room. 869 00:42:11,061 --> 00:42:11,421 Sam: Yeah. 870 00:42:11,991 --> 00:42:12,201 Yeah. 871 00:42:12,201 --> 00:42:13,281 And I'll add one other point. 872 00:42:13,281 --> 00:42:16,671 If you happen to be picking up the patient and you do suspect something 873 00:42:16,671 --> 00:42:21,051 like measles on the way in, notifying the ED ahead of time so you don't end 874 00:42:21,051 --> 00:42:24,971 up waiting on the wall when spreading this everywhere so they can get you 875 00:42:24,971 --> 00:42:29,181 directly to that negative isolation room would be exceedingly helpful. 876 00:42:29,311 --> 00:42:32,531 So that, you know, somebody can get in there quickly, examine the child and 877 00:42:32,531 --> 00:42:34,471 make sure nobody else gets exposed. 878 00:42:35,171 --> 00:42:37,271 So on that note, they're in the ED. 879 00:42:37,271 --> 00:42:40,271 We've got a bunch of questions we're gonna ask, and I thought the author 880 00:42:40,271 --> 00:42:42,521 did a great job just listing them. 881 00:42:42,521 --> 00:42:44,381 There's like 20 questions here. 882 00:42:44,381 --> 00:42:49,038 Everything from how long have you had fever, what did the initial rash look 883 00:42:49,038 --> 00:42:53,638 like, if there's already one, how did it spread from where to where did it occur 884 00:42:53,638 --> 00:42:56,578 in crops or did it spread gradually? 885 00:42:56,578 --> 00:42:57,328 Is it itchy? 886 00:42:57,328 --> 00:42:58,258 Is it painful? 887 00:42:58,508 --> 00:43:01,508 What kind of other symptoms were associated before the rash? 888 00:43:01,508 --> 00:43:03,428 Are they having any respiratory symptoms? 889 00:43:03,708 --> 00:43:07,218 And then kinda like screening for complications. 890 00:43:07,218 --> 00:43:10,008 Are they having any mental status problems, headaches? 891 00:43:10,058 --> 00:43:10,898 Are they acting funny? 892 00:43:10,898 --> 00:43:12,488 Are they having difficulty walking? 893 00:43:12,878 --> 00:43:15,608 They've been exposed from sick contacts at school. 894 00:43:15,738 --> 00:43:16,968 Who else is at home? 895 00:43:16,968 --> 00:43:19,548 And now we're kind of expanding these questions to who 896 00:43:19,548 --> 00:43:20,898 else may have been exposed. 897 00:43:20,898 --> 00:43:22,788 You know, is there anybody sick at home on chemo? 898 00:43:23,058 --> 00:43:26,473 Has cancer, is immunocompromised or is this patient have 899 00:43:26,473 --> 00:43:27,628 any of those risk factors? 900 00:43:27,838 --> 00:43:32,848 So a whole bunch of questions you gotta ask for the very quick and simple, 901 00:43:33,028 --> 00:43:34,888 Hey, here's a fever and a rash kid. 902 00:43:35,068 --> 00:43:35,338 Tim : Yeah. 903 00:43:35,458 --> 00:43:38,188 Sam: it's like, well, it's the quick and simple visit because I don't have to order 904 00:43:38,188 --> 00:43:41,848 a lot of testing, but I actually have a whole lot questions I've gotta ask. 905 00:43:42,198 --> 00:43:42,858 Tim : Absolutely. 906 00:43:43,048 --> 00:43:46,078 And again, this is a good example of like, if you've front loaded your 907 00:43:46,078 --> 00:43:49,498 mental work like we're doing right now, then it'll become natural because 908 00:43:49,498 --> 00:43:50,728 you'll see, you know, fever and rash. 909 00:43:50,728 --> 00:43:53,828 You're okay, you have a viral exam, goodbye, you go home but 910 00:43:53,828 --> 00:43:56,668 fever and rash, and there's something in you that resonates. 911 00:43:56,668 --> 00:43:59,968 There's something a little spark in you because you remember Dr. Ashoo saying, 912 00:43:59,968 --> 00:44:01,798 wait a minute, ask these questions. 913 00:44:02,178 --> 00:44:04,548 That's when you should stop and then try to remember what you 914 00:44:04,548 --> 00:44:05,658 can and look up what you can't. 915 00:44:05,658 --> 00:44:09,488 Because again, we can't remember everything off the top of our heads. 916 00:44:09,668 --> 00:44:13,638 A lot of our education just goes, and our training goes back to, is there 917 00:44:13,638 --> 00:44:15,108 something else that I'm missing? 918 00:44:15,168 --> 00:44:18,888 And you take that pause, that moment that you have to say, is this more 919 00:44:18,888 --> 00:44:20,978 than just a typical viral exanthem? 920 00:44:21,418 --> 00:44:23,683 Then you start thinking about measles, mumps, and varicella. 921 00:44:24,103 --> 00:44:27,243 And if it doesn't pass any of those red flags in your mind, great. 922 00:44:27,243 --> 00:44:28,053 If it does. 923 00:44:28,469 --> 00:44:32,759 Hey, pull up this article, look things up, ask the right questions, 924 00:44:32,759 --> 00:44:35,399 because there's no way in a busy shift that we're gonna remember these 925 00:44:35,399 --> 00:44:36,659 things off the top of our heads. 926 00:44:37,359 --> 00:44:37,659 Sam: Yeah. 927 00:44:37,659 --> 00:44:41,319 And speaking of that busy shift, your examination equally 928 00:44:41,319 --> 00:44:44,649 important may occur in triage. 929 00:44:44,829 --> 00:44:49,009 And it may not occur to you to check things like the inguinal area for 930 00:44:49,009 --> 00:44:54,194 lymphadenopathy or the scrotal area for testicular tenderness or swelling 931 00:44:54,194 --> 00:44:55,674 if you're considering orchitis. 932 00:44:55,691 --> 00:44:58,931 And so some of these things may be difficult to check out in the waiting 933 00:44:58,931 --> 00:45:02,411 room, and you may need to take that extra effort and go, I'm gonna bring you over 934 00:45:02,411 --> 00:45:06,821 here where there's a curtained area, and then I need to do this kind of exam. 935 00:45:06,911 --> 00:45:07,131 Tim : Mm. 936 00:45:07,211 --> 00:45:10,421 Sam: you may get a funny look from a parent going, why are you undressing 937 00:45:10,421 --> 00:45:14,411 my child who come in with a, you know, a cough congestion and a rash? 938 00:45:14,831 --> 00:45:17,171 And you go, okay, well let me explain what's going on here. 939 00:45:17,226 --> 00:45:18,476 Tim : We are very thorough here, ma'am. 940 00:45:18,748 --> 00:45:19,708 Sam: but for the right reasons. 941 00:45:20,083 --> 00:45:20,683 Tim : For the right reasons. 942 00:45:20,863 --> 00:45:23,873 You know, it also goes to our dynamic approach. 943 00:45:23,873 --> 00:45:27,293 We have an iterative way of seeing a patient, right? 944 00:45:27,293 --> 00:45:29,783 We don't wanna anchor and say, ah, fever and we're done. 945 00:45:30,253 --> 00:45:33,813 With the new information we have now, what are the new things I need to think about? 946 00:45:34,113 --> 00:45:35,463 And that's a great example. 947 00:45:35,493 --> 00:45:38,523 They come in and then the triage may also bias us. 948 00:45:39,183 --> 00:45:41,373 Triage is meant to just say, are you okay? 949 00:45:41,373 --> 00:45:41,913 Can you wait? 950 00:45:41,913 --> 00:45:42,243 Right? 951 00:45:42,693 --> 00:45:46,783 But we should really take that, read the nursing notes, read the triage notes. 952 00:45:47,233 --> 00:45:50,673 There's lots of little nuggets that sometimes are not repeated, but 953 00:45:50,913 --> 00:45:53,673 great opportunity to just rethink. 954 00:45:53,793 --> 00:45:55,293 Does this make sense? 955 00:45:55,533 --> 00:45:59,553 Why are you complaining of belly pain when you have a, you know, a little bit of 956 00:45:59,553 --> 00:46:01,653 arthralgia and maybe a cough or something? 957 00:46:01,838 --> 00:46:05,678 Oh, no, you have bronchitis as an example for mumps. 958 00:46:06,181 --> 00:46:08,923 Sam: And then we talk about diagnostic testing. 959 00:46:08,923 --> 00:46:10,303 We like to order a bunch of tests. 960 00:46:10,303 --> 00:46:15,133 These are mostly clinical in their presentation, and if you can identify 961 00:46:15,133 --> 00:46:18,823 the rash, that is sufficient, but if not, and there's a question, there 962 00:46:18,823 --> 00:46:22,033 is PCR testing for these viruses. 963 00:46:22,318 --> 00:46:22,618 Tim : Yeah. 964 00:46:22,918 --> 00:46:25,858 You know, and just to give you a little bit of a, kind of a behind the 965 00:46:25,858 --> 00:46:29,568 scenes of how we think about this when we're developing an article as editor 966 00:46:29,568 --> 00:46:34,058 in chief, we wanna make sure that this is scholarly and this is very 967 00:46:34,058 --> 00:46:36,008 helpful, but also practical, right? 968 00:46:36,008 --> 00:46:38,928 So we are always very careful about the messaging that we have, and Dr. Cavallaro 969 00:46:38,948 --> 00:46:41,408 did a fantastic job of balancing that out. 970 00:46:41,408 --> 00:46:44,408 So there's a lot of good, scholarly, nerdy things that we talked about. 971 00:46:44,618 --> 00:46:46,688 But when the rubber hits the road, what do you do? 972 00:46:46,838 --> 00:46:50,228 It's all clinical, so that I want to be the main message. 973 00:46:50,528 --> 00:46:54,668 You should trust your eyes and your ears, and if you're not sure, you can 974 00:46:54,668 --> 00:46:56,488 look up different reference images. 975 00:46:56,668 --> 00:47:01,088 So if at any way you're worried, treat it as if it's measles, mumps, rubella, 976 00:47:01,108 --> 00:47:04,918 varicella, because these tests won't necessarily come back immediately. 977 00:47:04,948 --> 00:47:09,173 However, either your public health department will ask for it or you're 978 00:47:09,173 --> 00:47:12,623 just, you know, let's just put it in the record or you're not sure. 979 00:47:13,043 --> 00:47:14,093 Most of these are PCR. 980 00:47:14,093 --> 00:47:18,113 So for example measles is a PCR in the nasal pharynx or oral pharynx. 981 00:47:18,413 --> 00:47:21,053 You can do it in measles, IGM serology. 982 00:47:21,053 --> 00:47:23,843 So the IGM as we remember is the early version of your 983 00:47:23,843 --> 00:47:25,433 IGs as opposed to your IgG. 984 00:47:26,133 --> 00:47:31,393 the IGM is better after the rash has actually come into view. 985 00:47:31,753 --> 00:47:33,373 Whereas the PCR can be at any time. 986 00:47:33,403 --> 00:47:36,133 'cause as we mentioned with measles, you're infectious four days 987 00:47:36,133 --> 00:47:37,483 before and until four days after. 988 00:47:37,483 --> 00:47:40,153 So PCR will work for any time for measles. 989 00:47:40,423 --> 00:47:43,813 The IgM is more specific after the rash. 990 00:47:43,933 --> 00:47:47,893 Four, most of the time that's when you're doing serologies because you see the rash. 991 00:47:48,223 --> 00:47:49,199 What i s this rash? 992 00:47:49,869 --> 00:47:54,944 For mumps similar thing you can do PCR mumps again, I encourage us to look 993 00:47:54,944 --> 00:47:58,254 these things up because, you know, you're you're asking me now, and I'm 994 00:47:58,254 --> 00:48:02,184 telling you, you ask me five hours from now when my coffee is worn off. 995 00:48:02,184 --> 00:48:05,094 And I don't know if I'm gonna tell you this, but mumps, the PCR is a 996 00:48:05,244 --> 00:48:10,884 buccal swab, specifically buccal swab, and then IGM serology for mumps. 997 00:48:11,154 --> 00:48:14,484 But if the person is vaccinated, it's not as reliable. 998 00:48:14,484 --> 00:48:18,774 So there's all these like ins and outs, intricacies, shout out, public health 999 00:48:19,054 --> 00:48:22,354 rubella similar thing is also the PCR. 1000 00:48:22,624 --> 00:48:26,164 You can do either IgM or IgG for rubella. 1001 00:48:26,524 --> 00:48:30,429 And then varicella of course is really kind of pathognomonic to be honest with 1002 00:48:30,429 --> 00:48:32,229 you, but you can do PCR for that as well. 1003 00:48:32,929 --> 00:48:36,709 Sam: Now I am curious, in your hospital you have PCR available for 1004 00:48:36,709 --> 00:48:37,949 these or are they all send outs? 1005 00:48:38,134 --> 00:48:40,988 Tim : These are all send outs for us, and I think that's true of most 1006 00:48:40,988 --> 00:48:45,308 hospitals, I would say, unless you're at a tertiary facility that has, you know, 1007 00:48:45,308 --> 00:48:47,138 research capability immediately there. 1008 00:48:47,138 --> 00:48:48,528 So , we send that out. 1009 00:48:48,888 --> 00:48:51,198 And the serologies for sure we send out. 1010 00:48:51,258 --> 00:48:52,518 I work in a county hospital. 1011 00:48:52,518 --> 00:48:55,251 We have a lot to offer, but, still , we need to send it out for 1012 00:48:55,251 --> 00:48:57,231 any community hospital for sure. 1013 00:48:57,231 --> 00:49:00,061 They're not gonna know right away, which is why I really emphasize 1014 00:49:00,391 --> 00:49:02,341 trusting your clinical diagnosis. 1015 00:49:02,341 --> 00:49:05,891 I would rather you be overprotective than underwhelmed. 1016 00:49:06,021 --> 00:49:10,251 It's always better to get people excited and the worst that we've 1017 00:49:10,251 --> 00:49:15,471 done is that we've taught the people around us to consider and just 1018 00:49:15,471 --> 00:49:19,371 sort of refresh the anxiety that we should have about these illnesses. 1019 00:49:19,771 --> 00:49:20,061 Sam: Okay. 1020 00:49:20,526 --> 00:49:23,916 And then there is the reporting responsibility. 1021 00:49:23,916 --> 00:49:27,156 So know your public health rules in whatever county you're in, but 1022 00:49:27,156 --> 00:49:29,826 all of these diseases should be reportable, especially, and that's 1023 00:49:29,826 --> 00:49:32,046 reportable based on suspicion. 1024 00:49:32,316 --> 00:49:35,676 You don't have to have a, you know, I am kind of hammering a nail and I've 1025 00:49:35,676 --> 00:49:38,676 made this diagnosis for sure, but if you're clinically suspected, that's 1026 00:49:38,676 --> 00:49:40,686 good enough for reporting and isolation. 1027 00:49:41,256 --> 00:49:43,116 And then treatment. 1028 00:49:43,176 --> 00:49:47,286 So what do we have in the way of treatment? 1029 00:49:47,316 --> 00:49:49,446 Let's just start with measles. 1030 00:49:49,611 --> 00:49:51,761 Tim : I'll just mention that your public health will ask there'll 1031 00:49:51,761 --> 00:49:54,381 be different tiers of reporting. 1032 00:49:54,381 --> 00:49:56,961 So measles is so bad, they need a phone call. 1033 00:49:57,021 --> 00:49:59,511 They need you to pick up the phone and call whomever. 1034 00:49:59,511 --> 00:50:02,151 There's always gonna be someone who can pick up the phone 1035 00:50:02,151 --> 00:50:03,111 even at three in the morning. 1036 00:50:03,561 --> 00:50:06,651 Something like Rubella, oftentimes, at least in Los Angeles 1037 00:50:06,651 --> 00:50:09,891 County, is a snail mail report. 1038 00:50:09,891 --> 00:50:12,871 They just kind of wanna know, just for your information et cetera. 1039 00:50:12,871 --> 00:50:17,441 So just be sure that you have that awesome chart plastered somewhere 1040 00:50:17,441 --> 00:50:22,701 on , your wallpaper of, of algorithms that you have around your doc box. 1041 00:50:23,101 --> 00:50:26,641 But getting back to what we do, let's say, I think this could be measles. 1042 00:50:27,191 --> 00:50:27,701 What do we do? 1043 00:50:28,031 --> 00:50:30,401 Measles, as you know, is going to be supportive. 1044 00:50:30,481 --> 00:50:35,566 In developing countries the morbidity increased with people who don't have 1045 00:50:35,566 --> 00:50:36,976 a lot of vitamin A in their diets. 1046 00:50:36,976 --> 00:50:41,429 And so the idea was in these resource countries, vitamin A supplementation, 1047 00:50:41,699 --> 00:50:46,319 that recommendation I've seen shift to the point where give vitamin A for anybody. 1048 00:50:46,319 --> 00:50:46,889 , And that's fine. 1049 00:50:46,889 --> 00:50:50,009 It's not going to save lives, but it may make them feel better. 1050 00:50:50,009 --> 00:50:53,789 It's just two doses, 24 hours apart, boost up their vitamins. 1051 00:50:53,849 --> 00:50:54,509 It's good for you. 1052 00:50:54,859 --> 00:50:56,813 I do have a really just brief case of this. 1053 00:50:56,863 --> 00:51:00,103 Family came in, in Los Angeles County we have people come to us 1054 00:51:00,103 --> 00:51:04,543 from all over the world all over the nation, come and go all the time. 1055 00:51:04,903 --> 00:51:07,693 So we're always sort of thinking about these things. 1056 00:51:08,023 --> 00:51:09,163 Family came from Pakistan. 1057 00:51:09,383 --> 00:51:11,783 They were so worried about measles. 1058 00:51:11,843 --> 00:51:13,253 No one had been vaccinated. 1059 00:51:13,733 --> 00:51:17,033 And I'm saying, ma'am, can I ask why are you, what is your concern? 1060 00:51:17,423 --> 00:51:21,593 And the child had had a rash, you know, two weeks ago in Pakistan. 1061 00:51:21,593 --> 00:51:22,763 That is completely resolved. 1062 00:51:23,093 --> 00:51:25,193 And just wanted us to make sure that it wasn't measles. 1063 00:51:25,193 --> 00:51:27,536 And I'm thinking to myself, okay, you know, I'm gonna try my 1064 00:51:27,536 --> 00:51:29,176 best, but I can't see anything. 1065 00:51:29,806 --> 00:51:32,596 She was so anxious that I said, listen, the only one thing that I 1066 00:51:32,596 --> 00:51:35,926 can do based on where you're coming from is to give you some Vitamin A. 1067 00:51:36,316 --> 00:51:37,546 And she was very happy with that. 1068 00:51:37,546 --> 00:51:37,726 Right. 1069 00:51:37,726 --> 00:51:40,636 Got her, got her door prize for coming in the emergency room department. 1070 00:51:41,026 --> 00:51:41,521 Everyone's great. 1071 00:51:41,701 --> 00:51:42,791 And , I wasn't concerned. 1072 00:51:42,831 --> 00:51:46,858 What she was describing did not seem to be something that I would associate 1073 00:51:46,898 --> 00:51:50,208 with measles, but it also keys into our anxiety that we've been talking about. 1074 00:51:50,223 --> 00:51:54,233 So the funny little twist to the story was that an old school pediatrician 1075 00:51:54,233 --> 00:51:59,279 later on saw this patient and chastised me for giving her vitamin A because 1076 00:51:59,279 --> 00:52:00,436 there's no evidence, et cetera. 1077 00:52:00,436 --> 00:52:01,696 And I, I just go, okay, great. 1078 00:52:01,696 --> 00:52:04,576 Like anything in emergency medicine, I'm happy to be wrong. 1079 00:52:04,606 --> 00:52:06,676 Or not, I'm happy to be criticized or not. 1080 00:52:06,676 --> 00:52:08,476 I'm just trying to be the best I can with what I got. 1081 00:52:08,476 --> 00:52:10,276 So a little bit of Vitamin A can't hurt you. 1082 00:52:10,456 --> 00:52:12,226 It really won't save you. 1083 00:52:12,496 --> 00:52:16,066 But , the thing to really think about is the post-exposure to 1084 00:52:16,066 --> 00:52:17,536 people who have not been vaccinated. 1085 00:52:17,536 --> 00:52:21,586 So if you have never been vaccinated, and let's say, I'm gonna make up the 1086 00:52:21,586 --> 00:52:25,766 scenario you know, little Johnny is three, has measles is okay to go home, 1087 00:52:26,156 --> 00:52:30,536 but his sister is five years old and no one's been vaccinated in the family. 1088 00:52:30,936 --> 00:52:34,086 She should get the MMR vaccine within 72 hours if she's an 1089 00:52:34,086 --> 00:52:35,166 otherwise healthy person. 1090 00:52:35,506 --> 00:52:39,361 Now we worry about people who can't get the vaccine, like for example 1091 00:52:39,441 --> 00:52:43,071 the immunocompromised, et cetera, or infants less than six months of 1092 00:52:43,071 --> 00:52:47,741 age they should get the IgG because that's gonna be more protective of 1093 00:52:47,741 --> 00:52:51,318 them, the immunoglobulin six months. 1094 00:52:51,318 --> 00:52:53,568 So, just to back up a little bit, you know, your first dose, you 1095 00:52:53,568 --> 00:52:56,658 typically get as an infant from 12 to 15 months, and that's gonna be 1096 00:52:56,658 --> 00:52:58,868 a really robust immuno response. 1097 00:52:59,138 --> 00:53:01,418 Your second dose is gonna be a booster in four to six years. 1098 00:53:01,778 --> 00:53:03,128 There are some people that can get it. 1099 00:53:03,218 --> 00:53:05,858 If there's an outbreak, you can get it you know, at six months of 1100 00:53:05,858 --> 00:53:07,328 age is early six months of age. 1101 00:53:07,878 --> 00:53:11,748 And that's really the earliest we'll often give it, but that first early 1102 00:53:11,748 --> 00:53:16,938 dose, as an exception, doesn't count as part of the two dose regimen. 1103 00:53:16,938 --> 00:53:21,528 So the idea is that infants just don't respond as well to the vaccines. 1104 00:53:21,858 --> 00:53:23,808 These things are all very calibrated over time. 1105 00:53:23,808 --> 00:53:25,968 We should really trust our decades of experience on this. 1106 00:53:26,238 --> 00:53:30,443 So if the kid comes in, let's say this is another case in which there's 1107 00:53:30,443 --> 00:53:33,683 international travel or an epidemic and someone's really interested in 1108 00:53:33,683 --> 00:53:36,973 getting it as an infant at seven months, eight months of age, 10 1109 00:53:36,973 --> 00:53:38,673 months of age, that's that's fine. 1110 00:53:38,673 --> 00:53:39,423 And that's okay. 1111 00:53:39,483 --> 00:53:42,033 It'll cover them probably for a few months, but they still should go 1112 00:53:42,033 --> 00:53:45,483 back on the regimen of the 12 to 15 months, first dose and their second 1113 00:53:45,483 --> 00:53:46,683 dose at four to six years of age. 1114 00:53:46,953 --> 00:53:49,873 So, to answer your question, more mostly supportive, but all of those 1115 00:53:49,873 --> 00:53:53,153 little intricate questions, as you mentioned in the appendices, make 1116 00:53:53,153 --> 00:53:54,953 sure that they get their follow up. 1117 00:53:54,953 --> 00:53:57,803 Make sure that you've kind of thought about this person thoroughly 1118 00:53:57,803 --> 00:53:59,273 and whoever else is in the family. 1119 00:53:59,303 --> 00:54:01,883 And then think about just, you know, good hydration. 1120 00:54:01,883 --> 00:54:03,573 That's the number one thing that's gonna hurt people that 1121 00:54:03,573 --> 00:54:04,893 are well enough to go home. 1122 00:54:04,983 --> 00:54:09,783 And then secondly is to make sure nobody else needs a post-exposure mMR vaccine. 1123 00:54:10,483 --> 00:54:10,773 Sam: Okay. 1124 00:54:11,148 --> 00:54:13,188 Two things, two questions. 1125 00:54:13,188 --> 00:54:15,348 First on the vitamin A issue. 1126 00:54:15,348 --> 00:54:18,958 So, if you're gonna provide some kind of supplementation, you do also have 1127 00:54:18,958 --> 00:54:23,038 to warn the family that they shouldn't overdose their child on vitamin A. 1128 00:54:23,038 --> 00:54:24,718 That's one of those that can be toxic, 1129 00:54:24,853 --> 00:54:25,363 Tim : yes. 1130 00:54:25,378 --> 00:54:26,278 Sam: and can build up. 1131 00:54:26,278 --> 00:54:28,288 So very important to mention that. 1132 00:54:28,568 --> 00:54:33,888 And then second, the IgG, like this immunoglobulin is not, I mean, I haven't 1133 00:54:33,888 --> 00:54:37,348 never actually asked my pharmacy to see if they even have it, but is that 1134 00:54:37,348 --> 00:54:40,573 something that's difficult to get or do you have to get that from like the health 1135 00:54:40,573 --> 00:54:41,833 department or where does that come from? 1136 00:54:42,007 --> 00:54:45,363 Tim : immunoglobulin, Is good for Kawasaki disease. 1137 00:54:45,363 --> 00:54:48,543 It's good for, you know, any of these things where you need to have a 1138 00:54:48,573 --> 00:54:50,883 biochemical mop in your blood, right? 1139 00:54:50,883 --> 00:54:52,533 Just like mops up all the junk. 1140 00:54:52,623 --> 00:54:52,983 Right? 1141 00:54:53,293 --> 00:54:56,013 So, it's available in many hospitals. 1142 00:54:56,163 --> 00:55:00,044 Sometimes if you have a, let's say a smaller community hospital, oftentimes 1143 00:55:00,044 --> 00:55:03,974 they'll have a network where the pharmacist can call either a satellite 1144 00:55:03,974 --> 00:55:05,984 pharmacy or an affiliated institution. 1145 00:55:05,984 --> 00:55:08,504 And you can have that shipped over within hours. 1146 00:55:08,504 --> 00:55:10,334 I wouldn't let the person go until they've gotten it. 1147 00:55:10,704 --> 00:55:16,314 So immunoglobulin it does cost $10,000 a shot, so you wanna really think about it. 1148 00:55:16,314 --> 00:55:19,071 But it's important in the people that are vulnerable. 1149 00:55:19,231 --> 00:55:22,411 But it's not so uncommon, Sam, it's not such a weirdo thing. 1150 00:55:22,411 --> 00:55:23,311 It's just something you gotta ask for. 1151 00:55:23,971 --> 00:55:27,481 Sam: Yeah, and this is not immunoglobulin that's specific to measles. 1152 00:55:27,481 --> 00:55:30,451 It's the generic immunoglobulin you'd give for multiple other 1153 00:55:30,451 --> 00:55:33,301 conditions, and Hopefully it's got some antibodies from measles in there. 1154 00:55:33,721 --> 00:55:34,171 Tim : that's right. 1155 00:55:34,651 --> 00:55:34,981 Sam: Perfect. 1156 00:55:35,161 --> 00:55:36,066 Tim : Infectious mop, 1157 00:55:36,766 --> 00:55:37,156 Sam: Okay. 1158 00:55:37,226 --> 00:55:37,856 Mumps. 1159 00:55:37,856 --> 00:55:41,036 So again, no treatment for mumps. 1160 00:55:41,036 --> 00:55:42,506 This is kind of one of those things. 1161 00:55:42,506 --> 00:55:45,416 You diagnose it great, but we don't have anything we're gonna 1162 00:55:45,416 --> 00:55:47,186 do to make it go away any faster. 1163 00:55:47,246 --> 00:55:47,486 Right. 1164 00:55:48,056 --> 00:55:48,236 Tim : Yeah. 1165 00:55:48,236 --> 00:55:50,216 Don't take any family photos in the next couple weeks. 1166 00:55:50,216 --> 00:55:54,453 Basically, you're gonna have a pretty swollen face, but it's supportive. 1167 00:55:54,453 --> 00:55:57,363 It's, you know, NSAIDs, it's lots of fluids. 1168 00:55:57,613 --> 00:55:58,963 You could try ice packs. 1169 00:55:58,993 --> 00:56:01,448 Although, you know, depending on how old the child is, they 1170 00:56:01,448 --> 00:56:02,858 may or may not tolerate it. 1171 00:56:03,238 --> 00:56:04,943 Sam: This is ice packs to their face. 1172 00:56:05,018 --> 00:56:05,528 Tim : Ice packs to the face. 1173 00:56:05,528 --> 00:56:07,343 You could even do ice packs to the groin. 1174 00:56:07,403 --> 00:56:10,853 No one likes any of these things, but you just do the best you can. 1175 00:56:10,853 --> 00:56:14,303 You could if it's really bad orchitis you could also wear, like, for example, 1176 00:56:14,303 --> 00:56:18,038 a jock strap, something supportive for males , and really just kind 1177 00:56:18,038 --> 00:56:20,208 of, you know, weather, the storm. 1178 00:56:20,308 --> 00:56:21,388 Sam: And no steroids. 1179 00:56:21,538 --> 00:56:22,468 Tim : and no steroids. 1180 00:56:22,498 --> 00:56:23,098 No steroids. 1181 00:56:23,098 --> 00:56:23,278 Yeah. 1182 00:56:23,278 --> 00:56:24,988 That won't, that won't help them potentially harm. 1183 00:56:25,633 --> 00:56:25,933 Sam: Okay. 1184 00:56:26,053 --> 00:56:29,113 Yeah, and I saw that the author mentioned the steroids might actually 1185 00:56:29,353 --> 00:56:33,103 decrease testosterone concentration and worsen testicular atrophy, 1186 00:56:33,103 --> 00:56:36,943 which kinda seems like a big deal if you're already concerned about that. 1187 00:56:37,138 --> 00:56:38,608 Tim : we need you to be strong like bull. 1188 00:56:39,133 --> 00:56:39,403 Sam: Yeah. 1189 00:56:39,553 --> 00:56:40,813 Uh, Okay. 1190 00:56:40,933 --> 00:56:43,993 Then rubella again, no treatment. 1191 00:56:44,023 --> 00:56:45,553 Just supportive care. 1192 00:56:45,553 --> 00:56:48,103 And make sure you isolate the people who are most at risk. 1193 00:56:48,328 --> 00:56:49,078 Tim : yeah, that's right. 1194 00:56:49,078 --> 00:56:51,844 And you know, full disclosure, I don't know that I've seen 1195 00:56:51,844 --> 00:56:53,344 a case of rubella either. 1196 00:56:53,654 --> 00:56:56,054 And again, it's not as common in this country, and maybe I called 1197 00:56:56,054 --> 00:56:57,344 it measles and it was rubella. 1198 00:56:57,654 --> 00:57:01,751 But it is reported to be a much milder version. 1199 00:57:01,804 --> 00:57:05,314 And for any of these children, I just worry about their hydration status. 1200 00:57:05,464 --> 00:57:08,644 So , that I think merits a quick, just a little discussion. 1201 00:57:08,644 --> 00:57:10,744 I think a lot of times people come to us in emergency care and they 1202 00:57:10,744 --> 00:57:14,944 just, even though we feel like it's obvious or pedantic or like too much, 1203 00:57:15,194 --> 00:57:16,244 you know, they just feel reassured. 1204 00:57:16,244 --> 00:57:18,054 We're like, Hey, listen, this is what I want you to do. 1205 00:57:18,054 --> 00:57:21,654 I want you to take a tablespoon of apple juice mixed with water, 1206 00:57:21,894 --> 00:57:24,354 and I want you to give a little sip every three to five minutes. 1207 00:57:24,504 --> 00:57:25,434 Or, what's a sippy cup? 1208 00:57:25,434 --> 00:57:28,204 What do they like to have, you know, or even like, Hey, will this child 1209 00:57:28,204 --> 00:57:32,104 take a popsicle great anything to get hydration in this child because of any 1210 00:57:32,104 --> 00:57:37,489 of these really inflammatory diseases, the child is gonna feel you know, 1211 00:57:37,519 --> 00:57:42,079 fussy and really cranky and not want to take in, and it's the dehydration 1212 00:57:42,079 --> 00:57:45,619 that hurts a lot of these children more and faster than anything else 1213 00:57:46,319 --> 00:57:46,859 Sam: Fantastic. 1214 00:57:47,559 --> 00:57:47,829 Okay. 1215 00:57:47,829 --> 00:57:49,179 And then Varicella. 1216 00:57:49,179 --> 00:57:53,949 So this is one where we actually do have a treatment that might be indicated, right? 1217 00:57:54,539 --> 00:57:54,904 Tim : we do. 1218 00:57:55,044 --> 00:57:58,554 And, you know, again, I always look this up because I feel like it's 1219 00:57:58,554 --> 00:58:00,984 changed over time and I will not try to. 1220 00:58:01,239 --> 00:58:02,199 commit it to memory. 1221 00:58:02,559 --> 00:58:05,439 Having said that, though Sam most cases don't need anything, really. 1222 00:58:05,439 --> 00:58:07,119 It is mostly supportive care. 1223 00:58:07,399 --> 00:58:12,529 But again, I, will look up myself this article and say, Hmm, what are the 1224 00:58:12,529 --> 00:58:18,419 indications for, for varicella treatment, 90% of the cases are gonna be isolation 1225 00:58:18,479 --> 00:58:21,169 Don't pick at the scabs, wash your hands. 1226 00:58:21,529 --> 00:58:25,259 Can't go back to school until all of the pimples are scabbed over. 1227 00:58:25,559 --> 00:58:29,129 Don't share toothbrushes like a, you know, a chicken pox party. 1228 00:58:29,429 --> 00:58:30,899 And that's pretty much it. 1229 00:58:31,469 --> 00:58:31,959 Sam: Perfect. 1230 00:58:32,659 --> 00:58:33,049 Okay. 1231 00:58:33,049 --> 00:58:38,179 And in the article, it looks like the author has said that the children at 1232 00:58:38,179 --> 00:58:42,979 highest risk who might be candidates for post-exposure prophylaxis are the 1233 00:58:42,979 --> 00:58:48,849 children who are unvaccinated and age over 12 in persons who are pregnant in 1234 00:58:48,849 --> 00:58:54,679 people who have chronic cutaneous diseases or chronic pulmonary disorders or those 1235 00:58:54,679 --> 00:58:59,849 with exposure, interestingly to long-term steroid therapy or salicylate therapy. 1236 00:59:00,029 --> 00:59:00,359 So, 1237 00:59:00,734 --> 00:59:01,094 Tim : yes. 1238 00:59:01,204 --> 00:59:03,934 You know, the older that you are when you first have varicella 1239 00:59:03,934 --> 00:59:06,994 chickenpox, the more miserable you are and the sicker you can get. 1240 00:59:07,424 --> 00:59:11,204 And again, like in a weird epidemiological way, the older 1241 00:59:11,204 --> 00:59:15,434 people before the vaccine have robust immunity because they got chickenpox 1242 00:59:15,434 --> 00:59:17,054 and they mostly did okay with it. 1243 00:59:17,564 --> 00:59:19,784 Uh, I wonder what it's gonna be like, and I don't know the answer 1244 00:59:19,784 --> 00:59:23,384 to this, but, you know, the MMRV is only a couple decades old. 1245 00:59:23,474 --> 00:59:28,604 And so I'm wondering what we're gonna see in the next 10 to 20 years when 1246 00:59:28,694 --> 00:59:35,364 these mostly millennials have gotten the MMRV and Gen Z, et cetera, and 1247 00:59:35,364 --> 00:59:38,724 they, in their middle age, how they're gonna do, because when they do get 1248 00:59:38,724 --> 00:59:40,464 chickenpox, it's the attenuated version. 1249 00:59:40,464 --> 00:59:41,994 It's a very mild version of it. 1250 00:59:42,294 --> 00:59:44,544 And sometimes it's hard to say, like, is that chickenpox? 1251 00:59:44,934 --> 00:59:47,244 And again, it's just trying to be more sensitive than specific. 1252 00:59:47,674 --> 00:59:51,609 , It's still important to go through those lists of risk factors as you 1253 00:59:51,609 --> 00:59:55,709 mentioned and verify and, I would err on the side of treatment, especially 1254 00:59:55,709 --> 01:00:00,239 since a lot of these diseases as they should be more and more rare, I think 1255 01:00:00,239 --> 01:00:04,319 that we should not kind of like rest in our laurels and say, it can't be fill 1256 01:00:04,319 --> 01:00:06,059 in the blank because fill in the blank. 1257 01:00:06,299 --> 01:00:07,679 We should just be open to it. 1258 01:00:07,679 --> 01:00:12,059 And I would rather over isolate overtreat over vaccinate because 1259 01:00:12,539 --> 01:00:13,469 they're becoming more rare. 1260 01:00:13,709 --> 01:00:14,339 Hallelujah. 1261 01:00:14,579 --> 01:00:16,889 But that means that we can let our guard down. 1262 01:00:17,589 --> 01:00:18,039 Sam: Perfect. 1263 01:00:18,739 --> 01:00:22,729 And this is one of those diseases where you can get post-exposure 1264 01:00:22,729 --> 01:00:24,739 prophylaxis with the vaccine. 1265 01:00:24,889 --> 01:00:32,189 So if you are un immunized age over a year and you've been exposed, you 1266 01:00:32,189 --> 01:00:35,549 have, you know, three to five days to go and get a vaccine and hopefully 1267 01:00:35,549 --> 01:00:37,109 prevent you from getting the illness. 1268 01:00:37,409 --> 01:00:37,889 Tim : That's right. 1269 01:00:38,199 --> 01:00:41,519 Again, that, that's gonna be a little tricky because, in a perfect world someone 1270 01:00:41,519 --> 01:00:44,369 who has, you know, great insurance, everything works out great for them. 1271 01:00:45,069 --> 01:00:47,829 they get in to see their PMD within three to five days? 1272 01:00:47,859 --> 01:00:48,849 Maybe, maybe not. 1273 01:00:49,549 --> 01:00:52,999 And so we have to rethink like uh, is this plan gonna work? 1274 01:00:53,059 --> 01:00:56,419 And, I'm not a big fan of doing things that are not necessary 1275 01:00:56,419 --> 01:00:57,469 in the emergency department. 1276 01:00:57,469 --> 01:01:00,019 And sometimes, you know, giving vaccines and all this kind of stuff is like, 1277 01:01:00,049 --> 01:01:03,769 oh, I've lost the opportunity for that primary care longitudinal care. 1278 01:01:04,099 --> 01:01:07,219 But this might be the case in which you say, let's order that vaccine 1279 01:01:07,249 --> 01:01:08,749 in the ED and just get it done. 1280 01:01:09,229 --> 01:01:09,619 Sam: Yeah. 1281 01:01:09,799 --> 01:01:13,219 Tim : make sure that I've written a little note or make sure they've communicated 1282 01:01:13,219 --> 01:01:15,289 that to the primary care physician. 1283 01:01:15,499 --> 01:01:16,369 This is what we did. 1284 01:01:16,489 --> 01:01:17,419 Please make a note of it. 1285 01:01:17,419 --> 01:01:18,829 Please update the vaccine record. 1286 01:01:19,529 --> 01:01:19,919 Sam: All right. 1287 01:01:19,949 --> 01:01:25,379 And on that note, there has been a lot of discussion, especially recently about 1288 01:01:25,379 --> 01:01:29,939 adverse events associated with vaccines, and I thought the author did a pretty 1289 01:01:29,939 --> 01:01:32,909 good job of tackling that in the article. 1290 01:01:33,149 --> 01:01:35,939 Where does that controversy come from? 1291 01:01:35,939 --> 01:01:37,769 What does that controversy surrounding you think? 1292 01:01:38,084 --> 01:01:42,824 Tim : Oh, we all know about our buddy who loved to have a falsified 1293 01:01:42,884 --> 01:01:47,354 article about autism I won't give, won't breathe life into the name. 1294 01:01:47,954 --> 01:01:50,844 But that's where that comes from, number one. 1295 01:01:50,844 --> 01:01:54,414 Number Number two, I think this also, I don't wanna get too philosophical with 1296 01:01:54,414 --> 01:02:01,604 you today, Sam, but think this also just goes to our role in our patients' lives in 1297 01:02:01,604 --> 01:02:04,004 public health and in the larger discourse. 1298 01:02:04,084 --> 01:02:07,984 I think it's important for people to see us as fighting for them 1299 01:02:08,074 --> 01:02:12,954 and individuals and not having any particular you know, espousing certain 1300 01:02:12,954 --> 01:02:14,844 beliefs or certain sides of whatever. 1301 01:02:15,114 --> 01:02:17,064 I think we just need to go like, what does this patient need in 1302 01:02:17,064 --> 01:02:18,654 front of me and just follow suit. 1303 01:02:19,104 --> 01:02:22,219 But we've broken trust, I think with , a lot of the public and 1304 01:02:22,219 --> 01:02:25,259 they don't believe us because they get news from different sources. 1305 01:02:25,259 --> 01:02:26,069 People don't believe. 1306 01:02:26,069 --> 01:02:28,529 They believe their own family who might have different ideas. 1307 01:02:28,559 --> 01:02:31,009 And that's, for pro and con. 1308 01:02:31,009 --> 01:02:36,429 They can be way too pro, like everyone needs all of these extra vaccines 1309 01:02:36,429 --> 01:02:37,569 and maybe they do, maybe they don't. 1310 01:02:37,866 --> 01:02:41,603 long story short, I would say this there is skepticism and that ties 1311 01:02:41,726 --> 01:02:44,816 into what I was mentioning before about our interaction with patients. 1312 01:02:45,026 --> 01:02:48,716 People need to see that we're there for them and that we're not there for a cause. 1313 01:02:48,716 --> 01:02:49,406 We're there for them. 1314 01:02:49,956 --> 01:02:53,846 And the reason I'm worried about you is because you as an individual 1315 01:02:53,846 --> 01:02:57,206 can get really hurt by measles mumps, rubella and varicella. 1316 01:02:57,206 --> 01:02:58,886 And I'm glad that you came in. 1317 01:02:58,886 --> 01:03:00,206 I'm glad today it's not measles. 1318 01:03:00,416 --> 01:03:04,376 But I'm glad today that we had a discussion because I would never want 1319 01:03:04,376 --> 01:03:08,903 you to have to go through what people went through, what our, grandparents, 1320 01:03:08,903 --> 01:03:10,223 great-grandparents had to go through. 1321 01:03:10,923 --> 01:03:12,003 We are so lucky. 1322 01:03:12,063 --> 01:03:13,233 This is a great opportunity. 1323 01:03:13,293 --> 01:03:14,793 I want you to talk to more people about it. 1324 01:03:14,793 --> 01:03:16,953 I encourage you to talk to your physician about it. 1325 01:03:17,293 --> 01:03:19,043 And I just kind of leave it at that. 1326 01:03:19,043 --> 01:03:21,463 'cause I wanna be seen as an asset. 1327 01:03:21,523 --> 01:03:23,533 I don't want to be seen as somebody who divides. 1328 01:03:23,533 --> 01:03:25,693 I wanna be seen as someone who can be supportive of them. 1329 01:03:25,953 --> 01:03:28,393 And I have to kind of navigate that discussion. 1330 01:03:28,393 --> 01:03:30,653 Again, this is just me, Sam, and i'm interested to see what your 1331 01:03:30,653 --> 01:03:32,633 thoughts are on the interaction. 1332 01:03:32,633 --> 01:03:36,489 But, you know, that's my strong feeling is that I do my best 1333 01:03:36,489 --> 01:03:39,009 to give what that person needs. 1334 01:03:39,009 --> 01:03:40,959 Do they need my heart, my head, or my hands. 1335 01:03:41,199 --> 01:03:43,599 And I try to fill in that blank as best as I can. 1336 01:03:43,599 --> 01:03:45,109 And I think people, when they see that you have good 1337 01:03:45,109 --> 01:03:46,839 intentions, they'll listen to you. 1338 01:03:46,839 --> 01:03:50,719 When you are just sort of speaking kind of at them, I don't know 1339 01:03:50,719 --> 01:03:51,679 how much they're gonna listen. 1340 01:03:52,379 --> 01:03:54,639 Sam: Yeah, I've always found that the strongest thing I could ever 1341 01:03:54,639 --> 01:03:57,159 say in that scenario was that all my children were vaccinated. 1342 01:03:57,859 --> 01:03:58,969 And I just kinda leave it at that. 1343 01:03:58,999 --> 01:03:59,719 I go, you know, 1344 01:03:59,914 --> 01:04:00,394 Tim : same here. 1345 01:04:00,719 --> 01:04:03,889 Sam: I do it for my children, so I would do it for anyone else's child. 1346 01:04:04,039 --> 01:04:04,489 Tim : I love that. 1347 01:04:04,969 --> 01:04:07,879 Sam: I think the author did a really good job of kind of just laying out the 1348 01:04:07,879 --> 01:04:12,744 evidence there, talking about things like febrile seizures and are they more common 1349 01:04:12,934 --> 01:04:18,514 with the MMR or the MMRV, you know, should a parent decide to split the MMR , from 1350 01:04:18,514 --> 01:04:21,724 the Varicella component and do those in two separate, you know, as long as you're 1351 01:04:21,724 --> 01:04:23,484 getting the vaccine, I don't really care. 1352 01:04:23,704 --> 01:04:27,404 It just means more trips to your pediatrician and maybe less compliance. 1353 01:04:27,528 --> 01:04:29,838 and then I thought the author also did a great job of just kind of 1354 01:04:29,838 --> 01:04:34,288 laying out the controversy there around autism and vaccines and the 1355 01:04:34,288 --> 01:04:37,793 history of it and all of the things that happened around that one article 1356 01:04:37,793 --> 01:04:41,723 that was redacted and the author who eventually had their license suspended. 1357 01:04:41,723 --> 01:04:43,853 So it's a great section to read. 1358 01:04:43,853 --> 01:04:46,953 It's good for your own education if you're a listener to understand 1359 01:04:46,953 --> 01:04:48,513 the history of that argument. 1360 01:04:48,813 --> 01:04:52,743 And then, you know, it gives you something to say about how the House of Medicine 1361 01:04:52,743 --> 01:04:57,913 responded to it which I think is helpful when people are genuinely concerned 1362 01:04:57,913 --> 01:04:59,413 and want to have a discussion about it. 1363 01:04:59,413 --> 01:05:01,663 Now, if they don't wanna have a discussion about it, there's no point 1364 01:05:01,803 --> 01:05:03,813 in reiterating all that information. 1365 01:05:03,993 --> 01:05:05,883 But if they do, it was a helpful section. 1366 01:05:06,378 --> 01:05:07,698 Tim : Well, you know, what would Mark Twain say? 1367 01:05:07,698 --> 01:05:10,348 He would say that a lie can get halfway around the world before 1368 01:05:10,348 --> 01:05:11,518 the truth puts his shoes on. 1369 01:05:11,728 --> 01:05:13,228 So , the damage is done. 1370 01:05:13,228 --> 01:05:15,058 And I think we need to recognize that. 1371 01:05:15,358 --> 01:05:18,718 And again, our personal relationship with patients is helpful, and I love that idea. 1372 01:05:18,718 --> 01:05:20,128 My children are vaccinated, your children. 1373 01:05:20,128 --> 01:05:22,648 I mean, it's a great way to connect that way. 1374 01:05:22,918 --> 01:05:28,258 Now, that's not to say that of course, MMR does have a big immunogenic response. 1375 01:05:28,258 --> 01:05:30,808 There's some kids that come in and I see after they got their MMR, their 1376 01:05:30,838 --> 01:05:33,178 whole little chunky thigh is red. 1377 01:05:33,478 --> 01:05:34,018 That's normal. 1378 01:05:34,018 --> 01:05:34,468 That's okay. 1379 01:05:34,468 --> 01:05:37,268 That's what we expect from MMR whether we separate or not. 1380 01:05:37,633 --> 01:05:39,073 You know, that's okay. 1381 01:05:39,073 --> 01:05:42,103 The old school pediatricians will say it's better to have just one bad day 1382 01:05:42,103 --> 01:05:44,107 than a multiple semi not good days. 1383 01:05:44,107 --> 01:05:46,001 Meaning you know, It's not fun to have a shot, then you might get 1384 01:05:46,001 --> 01:05:47,351 a little mild fever, et cetera. 1385 01:05:47,621 --> 01:05:48,371 That's normal. 1386 01:05:48,371 --> 01:05:48,851 That's good. 1387 01:05:48,851 --> 01:05:51,791 That means your immune system's working is so great that your immune system 1388 01:05:51,791 --> 01:05:54,041 says, I'm gonna do something with this. 1389 01:05:54,041 --> 01:05:54,941 That's a great thing. 1390 01:05:54,941 --> 01:05:58,971 So I think kind of normalizing what we expect contextualizing 1391 01:05:58,971 --> 01:06:02,491 for patients without overselling it, just balancing out the best. 1392 01:06:02,491 --> 01:06:07,111 And again, like there's some people who are like to have very niche vaccine 1393 01:06:07,111 --> 01:06:08,771 schedules and they have some conflict. 1394 01:06:08,791 --> 01:06:11,701 They check the star charts and the moon charts and decide when it should happen. 1395 01:06:12,121 --> 01:06:13,021 You know what, God love them. 1396 01:06:13,021 --> 01:06:15,451 As long as they get longitudinal care and they get it in, great. 1397 01:06:15,771 --> 01:06:17,481 I won't opine on that. 1398 01:06:17,481 --> 01:06:20,691 I'll just say, listen, there's a reason why we have a schedule. 1399 01:06:21,021 --> 01:06:22,041 It's cool. 1400 01:06:22,161 --> 01:06:23,181 Just keep going. 1401 01:06:23,361 --> 01:06:23,841 It's fine. 1402 01:06:24,541 --> 01:06:24,781 Sam: Yep. 1403 01:06:25,481 --> 01:06:27,551 All right, well that brings us to the end. 1404 01:06:27,551 --> 01:06:31,901 If you are listening and you are a subscriber, then this is the 1405 01:06:31,931 --> 01:06:34,751 peds EMP November, 2025 article. 1406 01:06:34,751 --> 01:06:40,111 It's got figures, pictures of the measles, the mumps and the rubella rashes. 1407 01:06:40,141 --> 01:06:41,641 The neonatal complications. 1408 01:06:41,641 --> 01:06:46,151 You can see common presentations and the exceedingly helpful appendix 1409 01:06:46,211 --> 01:06:50,511 of differential diagnosis for fever and rash on pages 16 and 17. 1410 01:06:50,740 --> 01:06:54,215 I highly recommend you just kind of keep this article close at hand. 1411 01:06:54,395 --> 01:06:57,825 There's so much information packed in here that it would be exceedingly 1412 01:06:57,825 --> 01:07:00,765 helpful the next time you see a child with fever and a rash. 1413 01:07:01,105 --> 01:07:04,078 And I wanna say thanks Tim for being on the podcast. 1414 01:07:04,315 --> 01:07:05,665 Tim : Sam, thanks for having me. 1415 01:07:06,161 --> 01:07:07,571 Been meaning to come on for a long time. 1416 01:07:07,571 --> 01:07:11,081 I'm glad we finally got a chance to connect and I love what you're doing. 1417 01:07:11,441 --> 01:07:11,861 Keep it up. 1418 01:07:12,561 --> 01:07:12,891 Sam: Yeah. 1419 01:07:12,951 --> 01:07:13,881 Thank you very much. 1420 01:07:13,881 --> 01:07:16,671 This is a exceedingly important topic and definitely something 1421 01:07:16,671 --> 01:07:18,711 we're gonna see more of in the ED. 1422 01:07:18,961 --> 01:07:22,171 Before we leave, tell me about your podcast. 1423 01:07:22,171 --> 01:07:22,831 Let's hear about it. 1424 01:07:22,876 --> 01:07:23,086 Tim : you. 1425 01:07:23,086 --> 01:07:25,200 Uh, The Pediatric Emergency Playbook. 1426 01:07:25,450 --> 01:07:27,180 So I'm your host and coach there. 1427 01:07:27,350 --> 01:07:30,482 We do a monthly podcast where I think of this way of all the things 1428 01:07:30,482 --> 01:07:33,842 that I keep telling my residents and fellows and lecture about. 1429 01:07:33,842 --> 01:07:38,312 I go, wow, wouldn't it be nice if I just spoken to the mic 1430 01:07:38,342 --> 01:07:39,962 as if I'm talking just to you? 1431 01:07:39,962 --> 01:07:43,802 And I say, let's talk about, we just had a talk on congenital heart disease. 1432 01:07:43,952 --> 01:07:47,787 So , I try to make it, you know, a bit of a conversational type of tone. 1433 01:07:47,787 --> 01:07:50,607 I try to bring up cases, bring up the latest research, I tell 1434 01:07:50,607 --> 01:07:54,687 you what is established research and what is my practice and I 1435 01:07:54,687 --> 01:07:55,527 just wanna get it out there. 1436 01:07:55,527 --> 01:07:59,797 It's in a 152 countries out there in the world, and I love that 1437 01:07:59,797 --> 01:08:01,607 I'm able to just shout it out. 1438 01:08:01,807 --> 01:08:04,937 It's so amazing, and you get the same thing too Sam, is that you get people 1439 01:08:04,937 --> 01:08:08,837 from all over the place saying, I listened to this and I applied it the 1440 01:08:08,837 --> 01:08:10,787 next day, and it's just so fulfilling. 1441 01:08:11,067 --> 01:08:14,517 Please have a listen or tell me what you'd like to hear more of, less of. 1442 01:08:14,517 --> 01:08:17,007 And I, I'd love to be there to meet your needs. 1443 01:08:17,697 --> 01:08:18,177 Sam: Awesome. 1444 01:08:18,177 --> 01:08:20,637 And we'll put a link to that in the show notes. 1445 01:08:20,637 --> 01:08:23,397 If you are not a current listener, I'd highly recommend you go 1446 01:08:23,397 --> 01:08:27,477 become one and improve your pediatric emergency education. 1447 01:08:27,817 --> 01:08:32,797 Thanks again for being on the podcast and until next time, be safe everyone. 1448 01:08:33,147 --> 01:08:34,967 And that's a wrap for this month's episode. 1449 01:08:35,007 --> 01:08:37,587 I hope you found it educational and informative. 1450 01:08:37,787 --> 01:08:42,647 Don't forget to go to ebmedicine.net to read the article and claim your CME. 1451 01:08:42,817 --> 01:08:46,007 And of course, check out all three of the journals and the multitude of 1452 01:08:46,007 --> 01:08:50,367 resources available to you, both for emergency medicine, pediatric emergency 1453 01:08:50,367 --> 01:08:52,637 medicine, and evidence based urgent care. 1454 01:08:52,947 --> 01:08:54,917 Until next time, everyone be safe.