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- <silence> Welcome
everyone to the Becker's

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Healthcare podcast series.

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I'm Maria Moham, writer

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and moderator with Becker's Healthcare.

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I'm absolutely thrilled
to have with me today Dr.

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Nick Capi, director of Infusion Oncology

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and investigational drug pharmacy
services at the University

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of California San Francisco.

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Doctor, it's very nice to
have you on the podcast today.

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To get us started, would
you mind please introducing

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yourself and telling us a
bit about your background?

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- Absolutely, and thank you for having me.

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As you mentioned, my name is Nick Capote,

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and, uh, I live in San Francisco

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and I'm fortunate to work at UCSF Health.

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Uh, I am one

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of the pharmacy directors
within the pharmacy department.

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We have a, a rather large
pharmacy department supporting the

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overall institution, uh,
for clinical services

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as well as research.

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And fortunate to be able to
call myself a team member

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and oversee oncology infusion
and investigational drugs.

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You know, fortunate is a word
I used when associating myself

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with UCSF Health in
terms of my background.

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I'm also fortunate to have
experienced a diversity

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of practice environments,
uh, and leadership styles.

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Uh, being in leadership, the
ability to gain a variety

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of perspectives is really important to me.

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Way back when I was doing
my pharmacy school training,

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the didactic portion of
pharmacy, uh, I was in Memphis,

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Tennessee at University of
Tennessee Health Science Center,

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and it was there that I
gained a really just immense

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appreciation for the clinical
application of pharmacy.

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It really opened my eyes to
what pharmacists could do, uh,

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on the healthcare team, uh,
elbow to elbow with other,

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uh, practitioners.

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Uh, after that, I completed two years

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of pharmacy residency training in Madison,

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Wisconsin at University
of Wisconsin Health, uh,

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the big academic medical
center there in Madison,

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and that was a residency
program focused on practice

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and effective implementation

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of change management and leadership.

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After that, I took my first
role managing acute care

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pharmacy operations at
Tufts Medical Center.

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Uh, essentially what that
means is getting the, uh,

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medications and managing the
processes for those medications

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to our patients that are in
our embedded inpatient units,

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as well as to some of our
outpatient areas, whether they're

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procedural, uh, or, uh, infusion

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or other outpatient clinic areas.

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Um, during my time at Tufts
Medical Center, I was able

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to take on more responsibility
over those three years within

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the pharmacy department

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and began the formation

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of the first home infusion
service for the system.

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And then most recently, in
2022, I made the transition

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to director of pharmacy
role at UCSF Health.

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So just over 3000 miles from Boston

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where I've been for the past six years.

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Uh, now I call San Francisco home,

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and I'm fortunate to serve

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as several pharmacy
teams that I represent.

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- Wonderful, wonderful.

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Thank you so much for giving
us that background on yourself

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and what you're currently doing right now.

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Um, two really jump into
the questions today.

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The first thing I really
wanted to ask you is

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what are the biggest
issues you're following in

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healthcare in 2024?

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- Sure. Well, there's a lot of them, uh,

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but I'll focus on a couple,
uh, for the, uh, purpose

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of time, uh, one of which
is workforce trends,

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and secondly, uh, what's
going on in the payer space.

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Uh, payers and insurance, uh,

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and health plans are always
keeping us on our toes.

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Uh, so I'll start with workforce trends.

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Um, specifically focusing
on the pharmacy workforce is

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that really is where I focus

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and spend my day to day, um,
within the pharmacy department.

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Um, some trends to take
note of is that applicants

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to schools and colleges of
pharmacy are down as well

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as applicants to residency
training programs.

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So that, that's our pipeline.

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And it's so important that
we're not only making sure that

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we have larger number

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of applicants per fair within our schools

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and colleges of pharmacy,
making sure that we are, uh,

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training the, the best and the brightest,

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but also making sure that we have, um,

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our training programs constantly fed

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with those high quality,
uh, applicants going

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through our schools and
colleges of pharmacy.

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So, interestingly enough, uh,

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there has been an obvious
shift in other sectors

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of pharmacy, uh, as well
that are, it's just kind

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of going in parallel with the trend

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that I just mentioned in terms
of applications being down

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to schools as well as training programs.

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Traditional areas of pharmacy
have been, uh, hospitals

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and health systems as well as community

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and independent pharmacies,
um, independence

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and chains, I should say.

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Um, but less traditional,
uh, yet emerging.

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More and more are
pharmacists going to work

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for drug manufacturers?

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This isn't anything new,

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but it looks like the,
the trend is increasing,

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and this is great.

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We want to have pharmacists
represented in the

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pharmaceutical industry.

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Uh, however we are seeing

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that shift from the more
traditional practice areas, one

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of which i, I work in myself,

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and so we're just trying
to make sure that we have

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a good sense of how that
is affecting, uh, the pool

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of applicants that we are
ultimately looking for, uh,

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for our needs, uh, in the
health system to take care

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of our patients within our practice model.

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Um, I'll also note that management

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and application of pharmacy
services are more complicated

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than ever, thus needing
to, to bolster, um,

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with high quality applicants
and, and pharmacists.

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And then another interesting

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and related trend in the
workforce is the regular closure

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of train of chain

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and independent pharmacies, uh, though

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for different reasons when
you compare chain versus

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independent, so independence,
uh, it seems like a lot of

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that is related to the
closures of, related

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to if those locations are, continue

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to be financially viable.

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Um, there's a lot that goes into it.

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Reimbursement models as well
as competition in addition

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to the availability of pharmacists
and pharmacy technicians.

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And then second to that,
focusing more on the change.

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You're seeing a lot of
consolidation of locations, brick

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and mortar locations.

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You're seeing, uh,
various pain pharmacies,

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specifically I'll, I'll
call out Walgreens,

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leveraging robotics
automation and central fill.

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Uh, in fact, in 2022 in October,

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there was a Wall Street Journal
article pointing out about

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Walgreen's strategy to centralize
and leverage automation

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and robotics to, uh,

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support their pharmacy
operations, uh, nationwide.

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And what that's translated
into it looks like is, uh,

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some consolidation of some
physical pharmacy locations, uh,

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potentially threatening
access pharmacy services.

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And then the second trend
that I'm monitoring has to do

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with payer activity,
specifically as it relates

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to shifting patients to sites
of care that payers, uh,

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deem to be lower cost.

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And my position is that there
should be incentives in place

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for a shared provider and
patient decision when a patient

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is, say for example, getting an infusion,

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the health system should
be doing everything it can

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to promote access while ensuring safety

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and effectiveness of therapy.

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Um, however, when a payer has
a policy that places a lot

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of risk on the health system,
by shifting those patients

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and their infusions to
a, uh, say, site of care

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that's lower cost for the payer, um,

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while the health system is still acquiring

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and handling an incredibly expensive, uh,

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and complicated drug, uh, the
safety profile of that episode

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of care has to be considered.

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We are seeing more and more
monoclonal antibodies, uh, types

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of medications that produce
a higher immunogenic response

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than most other class of
medications being forced decisive

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care that are typically
less equipped to manage or

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or less familiar with these therapies.

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So these shifts can be prob
problematic as the bottom line,

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uh, when mandated, uh,
without that shared provider

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and patient decision making.

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My hope is that we can establish
our own infrastructure fast

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enough to minimize any negative
impacts to our patients.

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The silver lining in all

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of this is health systems are
incentivized more than ever

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to invest in their own infrastructure

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to meet the patient where they are.

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I just wish the patient provider
could decide which resource

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that the health system they should

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utilize rather than the payer.

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But we are moving in the direction

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of making a more well-rounded side

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of care strategy in the
example that I gave.

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So those are a couple
trends that I'm watching,

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but <laugh> many more that

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we probably don't have time for today.

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- Yeah, yeah, absolutely.
Thank you so much for sharing.

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That is very insightful, um, especially

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to me in our audience.

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The next thing that I
wanted to ask you about,

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and maybe you kind of
answered it already in the,

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in the last question,

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but what are you most
excited about right now

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and what does making you nervous,

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whether it's something
you're dealing with, um,

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in your job description or
something that you're watching?

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- So I'm a bit of a technology nerd,

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and I really like the
technical side of any process.

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Um, in fact, before I
was a pre-pharmacy major,

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I was a mechanical engineering major,

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and I still have that
technical interest today, uh,

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that drove me to potentially
consider an engineering major.

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So I guess I'm most
excited about technology

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and what promises it
might hold for healthcare.

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Hospitals and health systems
have traditionally been slower

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to adopt these technologies for a myriad

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of reasons we don't have to get into.

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But the bottom line is
artificial intelligence,

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what everyone is talking about it,

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it will impact healthcare
in one way or another

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and hopefully for the better.

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Um, the reason I'm

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so confident in this projection
is I understand the iter

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iterative cycle of this technology

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to be much faster than any
technology we've seen before.

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While other technologies
have iterated on themselves

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o over the course of years,

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this one is iterating on itself
over the course of months

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and will probably continue to get faster,

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um, to maybe weeks.

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Uh, it seems like so many
people are working on solutions.

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Uh, a friend of mine who lives
in the Bay Area, um, close

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to me who I was with just this weekend,

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is working on an AI enabled technology

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that would allow practitioners
in the primary care

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environment specifically

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to research the most
evidence-based options

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for patients faster than ever,
sift through the guidelines,

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sift through the evidence,
and integrate those decisions,

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uh, into their practice,
into the health record, uh,

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technologies that we are adopting, uh,

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as soon as they hit the market.

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So not so much the artificial
intelligence probably being

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slow to adopt in healthcare,

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but technologies that we are
adopting that make me excited,

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uh, are promising and
very complex drugs, uh,

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specifically in the oncology
world, bispecific antibodies

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and chimeric antigen
receptor t-cell therapies

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while CAR T has been around
since 2017 with the introduction

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of Kymriah, we literally have hundreds

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of these in the drug pipeline
now for, while we only had

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to worry about a couple, we
have many coming at us in the

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coming years that are looking
at FDA approval potentially.

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Uh, and for many disease
states more than just cancer.

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Uh, at UCSF, we are working
on improving the care journey

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for the patient by allowing
an outpatient episode

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of care for these therapies.

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So that's specifically,
uh, what we're working on,

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not only adopting these as fast as we can

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where they make sense within
our care portfolio, um,

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but also allowing an outpatient episode

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of care rather than keeping

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that patient confined to a hospital bed.

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So those are just some examples
of things I'm excited for,

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things that we're working on, um,

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and what's to come
hopefully in the future.

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- Yeah, yeah, absolutely.
Thank you so much for sharing.

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And doctor, before I let you
go, the last thing I wanted

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to ask you is, what would
the most effective healthcare

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leaders need in order to be
successful in the next two

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to three years, would you say?

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- I think the biggest thing for
me is I think about the team

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that I support and

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as I observe friends
within my own organization

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and the organizations that
I've been fortunate enough

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to be a part of and serve,
is willingness for leaders

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to invest in their people
through the development

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of transferable skills.

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So more specifically,

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what worries me is the continued
exodus from certain sectors

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of healthcare or healthcare
altogether by folks

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who have simply become disengaged
from their current roles

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and see no way through,
uh, their current role

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because either they've
maxed out, uh, in terms

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of their advancement or they
just don't have the skills

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to self-perceived more than anything

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that they don't have the
skills to advance in a way that

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they would want to, or
they just don't know

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what the next step for them could be.

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So, you know, some examples
of transferable skills

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that I'm talking about
are, it sounds simple,

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but it's actually quite complex,
is how to implement change,

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how to take a process or problem,
identify the root issues,

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and put together a team

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and a scoped approach for that team

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to tackle, uh, and improve.

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And it doesn't have to
be done in a vacuum,

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but to be able to take
a problem, break it down

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to its simple parts and move forward.

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And effective change is I think one

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of the most important things

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that our healthcare system needs.

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And that transferable skill
is incredibly important.

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I think also how to navigate the politics

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and bureaucracy of an organization.

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Every organization has them,
whether we want to admit it

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or not, but few people are equipped

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to handle these effectively.

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Uh, it's stressful situations,

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but there are also potential
high opportunity situations.

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A mentor of mine once told me

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to never let a good crisis go to waste.

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Um, so you've seen a lot of
good advancements come out of

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what initially seemed like a crisis.

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Uh, you can see the covid
situation as an example.

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While of course it was detrimental society

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to society in a myriad of ways,

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there had been some really
significant practice

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changes that have come from it.

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Uh, and finally the, the
last transferable skill

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that I'll touch on is how to establish

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and build a network over time.

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A lot of people aren't taught this, uh,

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but it's really effective
in bringing back new ideas

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for consideration and keeping

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that engagement within your own practice

321
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or profession really fresh.

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So I'll just reiterate that I
think the most effective, uh,

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healthcare leaders need to be successful,

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or whether it's healthcare leaders

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00:13:40,145 --> 00:13:43,145
or aspiring healthcare leaders,
it's that willingness to,

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00:13:43,445 --> 00:13:46,825
to find or if you're a leader,
to invest in their people

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through the development
of transferable skills.

328
00:13:50,585 --> 00:13:53,715
- Wonderful. Yeah, I really
appreciate you talking about

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everything that we discussed today

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00:13:55,255 --> 00:13:56,835
and for those final thoughts.

331
00:13:56,945 --> 00:13:59,755
It's definitely been an amazing
and informative discussion.

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00:13:59,935 --> 00:14:01,155
So again, I wanna thank you so much

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00:14:01,155 --> 00:14:03,635
for coming back on
Becker's Healthcare, um,

334
00:14:03,635 --> 00:14:05,315
and I look forward to
connecting with you again soon.

335
00:14:06,705 --> 00:14:08,775
- Thank you so much. It's
been my pleasure. <silence>.

