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This is the Art Beauty podcast where we
tell the real truth about the fake shit.

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Hi, everybody.

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I'm Amber. Today,
my fabulous co-host is Dr.

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Corey L Hartman.

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He is a board certified dermatologist
and the founder and medical director

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of Getting That Right of Skin Wellness
Dermatology in Birmingham, Alabama.

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Thank you so much for joining us today.

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Oh, it's my pleasure and honor to be here.

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Amazing. And you know what?

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I try to memorize those
and really get them down.

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But sometimes it's like,
okay, let me just let me just check in.

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Make sure. Yeah. Okay.

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So today we are talking about something
that I think might be, you know,

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I guess the technical thing
is better than sliced bread, but

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better than Botox
because it's going to rival Botox.

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It's called Daxxify.

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And we we're going to get so into that.

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But before we do, how are things
in Birmingham, Alabama, today?

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Oh, it's a beautiful day in Birmingham.

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It's a crisp, like 70 degrees.

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The sun is shining, it feels like fall.

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And I'm really happy about that

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because it can take a long time for people
to show up around here.

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I'm like, giggling in my heart
because in New York, like,

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a 70 is like still summer, you know?

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We're like, Oh, yeah,
it's like a summer day here. Yay!

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I'm going to a baseball game this weekend,
and I'm like, I'm going to be in, like,

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a T-shirt shirt and tank top, and I know
you're probably zipped up there.

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Yeah. But the half zips already.

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Yeah. Yeah.

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You know, my parents are in Florida,
so I get it.

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It's like once you hit 60,
it's winter, and it's.

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Exactly

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as we can.

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Well, good to hear it there.

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You know, I want to get right into this
because I hadn't

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heard about Daxxify but that's
because it was just FDA approved.

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I think it's September 8th.

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So I'm going to just shut up

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and let you tell us all about this.

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So what is Daxxify Yes, well,
we are all very excited.

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They got their produce
for date on September 8th.

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It all went through the FDA as planned.

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We have been waiting and anticipating

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and hearing about Taxify
for about four years now.

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Actually.

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And there were just a lot of issues
with development and then there were

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the issues with COVID
that delayed the FDA's approval.

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But we've heard from the beginning
that it was going to change the market

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because it's going to bring a novel way
to treat our lines and wrinkles

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that none of the other products
on the market currently do.

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So that's great.

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It's like an innovation
in 40 years that we hadn't really seen.

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It's claim to fame, is that it?

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Last six months,
a lot of my patients have had trouble

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maintaining their duration
on their neurotoxin here lately.

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I'm not sure what that's about.

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Some have found different success
with other products,

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but there is a large market out there
for people who are looking for duration.

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They looking for something
that will take them farther

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so they don't have to have injections
quite so frequently.

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The injections aren't a big deal,
we all know that.

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But they're, you know,
every little inconvenience in our busy

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lives that we can save us a trip,
then we want to do it.

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So I think that that's going to really be
the beautiful thing about Taxify,

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which everybody has shortened to taxi.

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That's right.

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First part of the generic,
the name, the molecular name.

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So they all ended in botulinum.
There's only a botulinum

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abo botulinum and now there's Dex Ebucks.

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Alina, the taxi
just sounds a lot easier to say to me.

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I don't. Know.

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All right.

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So we're going to call it taxi,
but is it okay if I walk on the bridge?

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That's the name.

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That's the official name is Taxify,
but we're calling it that.

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All right.

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So to be clear, so Daxy is now it's

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the first neural modulator that is not.

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But it has a different way of
of affecting the nerve.

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Correct. Do you want to get into with you?

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But essentially what we're talking about
is a new something.

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You can hit the mark.

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Now, Botox just had
I think it's the 33rd birthday of 30th.

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Now, Botox has been on the market for.

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Well, for many 20.

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20, 24, 24 cosmetic.

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But it came out in 1989. Yes, yes. Yeah.

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Well studied.

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I use it now when I'm seeing Botox.

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I know that there are many variations,
so I'm going to call it,

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but I'm going to call Botox.

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We'll know that there's a different.

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But essentially that's been

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the only way that you can go.

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And I happen to know
I go every every three months.

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I'm in my doctor's office now.

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Botox is a company made last year.

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I did a little research, $4.7

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billion for their parent company.

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I mean, I

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was responsible for
like at least four payments towards that.

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Okay.

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So I'm super, super excited about this.

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But I want to be clear
because Doxy is very, very new

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that are you from
what I've heard, like not a lot of doctors

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even have their hands on this yet,
have you?

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Oh, so the only people who have

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any experience with, you know,
the people who did the clinical trials

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and we were not a clinical trial site,
we do injectable trials.

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We were not a part of that site.

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However, they are rolling this out
in a very deliberate,

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very smart and thoughtful way
because these days, you know,

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we haven't had such a big rollout

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since the days of social media
really becoming a thing.

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And there have been some missteps
with other companies where the education

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and the implementation of how
to use the product wasn't exactly right

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and it got out that it didn't work
when it really wasn't

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anything wrong with the product.
It was just sort of snap, was it

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who was using it
and how they were doing it.

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So they're being very specific
about how they let this product get out.

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The first rollout
is going to be very select

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doctors

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and for about three months
that's all you're going to have.

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They're mandating that you go
to their headquarters in Nashville

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to be trained and learn all about
the different intricacies of the molecule.

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There are four different botulinum
on the market now.

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Botox, despite Zemin and Jibo,

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they all have their own individual
little personalities, but at their heart

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they all stop
the transfer of acetylcholine,

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which makes the nerve
make the muscle fire.

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So if you stop that synaptic or transfer,

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then the muscle won't work because there's
no nerve firing it to work.

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And that's how we relax the muscles
to smooth out the lines

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of expression in our faces.

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Botox itself
has a medical indications as well.

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It was the first to the market.

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It's kind of like the Kleenex of tissue.

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We call it elbow, but they're different
brands that are available.

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It's just they don't have market share.

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But Botox specifically

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was indicated first for sweating,
I believe.

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Now it's used for like a million different
things, migraines toward a call.

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Is there, you know, every specialty
it seems like, is finding a use.

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For depression and clinical depression.

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But I was saying it makes me feel way less
depressed every time I go get my Botox.

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So, I mean, I. Love that study.

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I saw that recent study

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that came out that suggested
that it actually affects serotonin levels.

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You know, we've said for a time now,
we know that it stimulates collagen.

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We know that it can
maybe impact oil production,

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but it also releases endorphins.

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So it just makes you feel good.

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So it's it's a corollary that you would
think that it would also treat depression.

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So we're excited about that.

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But that's it, too,
just to kind of continue the discussion

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about the different options,
all four of those options, while they have

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their own specific characteristics,
like some

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are more purified, that semen doesn't
have this additional protein.

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This sport is a smaller molecule.

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It's it has a wider diffusion area.

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So it can give a wider area of effect.

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It comes on fast or maybe like two days
as compared to five days.

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I think on the issue of duration,

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all of these products on paper
and in the studies lasted for months.

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Now patients will tell you different
things

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based upon their different experiences.

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And I say everybody's going to have a
different reaction to different products.

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You're going to figure out
the one that works, the best for you.

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I think a lot of it has to do with the
circumstances surrounding the treatment.

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You know, if you like the doctor more,
if you got a deal

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or if it was a better environment,
then you may have

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a different experience
with that product that impacts your

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way of viewing it,

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but on paper, all for months,
because they all bind

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with a human protein and albumin protein,

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that's how they bind

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dak sapphire
doxy is going to bind with a peptide

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and this peptide binding
is thought to enhance the absorption

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into the skin
which affects the muscle, stops that trans

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fur of acetylcholine
to make the nerves fire,

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to stop the muscle from being active
for a longer period of time.

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That's the thought.

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Now that's what we know.

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That's what they seem
to be hanging their hats on.

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I am going to be the first one in my area
to have it.

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I can't wait.

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I have my training date.

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Yes, December 4th
I'm headed to Italy to learn all about it

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and I'll have it first in the area.

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So that's when I'm going to be able
to really get my hands on it

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and learn the different characteristics.

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Does it feel lighter?

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When does it come on, you know,
how much does it spread?

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How much are patients aware of it?

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I have a large

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number of

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patients in my practice
who have started to lose efficacy

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to really all of the products,
and that's a terrible place to be.

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So we're really happy that we have options
now, even if it doesn't last

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six months for them, it'll give them more
than they're getting now.

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And I think that it's good
to have another option.

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You know, when you say lose efficacy,
like how long are we talking now?

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Right? I mean,
it has to work for a little bit, but.

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Yeah, a little bit.

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I mean, I've seen patients
who have as little as 3 to 4 weeks. Oh.

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Yeah, I know, I know.

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And is that is that so?

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Is it I mean, look,
when I get it done, I would say like it

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takes about 5 to 7 days to, you know, as

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you said, hit kick in work, take effect.

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And then,

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you know, it's not totally frozen
for three months.

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You know, it starts to gradually wear off.

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But you're talking me.

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But by the end of 3 to 4 weeks,
they've got no nothing.

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I'm talking they're back to baseline

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now let me tell you
I know it well and it gets even worse.

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There are very few number,

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very few people that I know of
in my practice who get nothing.

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One of them works for me in the front.

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Michel, and we put it
we can put 50 units of Botox

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in our forehead
and tomorrow it's going to be moving.

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So she's really excited.

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Yeah, I tried to get my block for her,
which was the botulinum toxin B,

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which we don't have any available
brands in America,

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but it's only available in Europe
and it's even more difficult

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to get it these days.

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So it's it's not so okay.

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Of course, there's so many questions
when I ask you right now.

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But going back to

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so we're talking

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about efficacy, you know,
this is something that is very new.

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And I just have to ask you,

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you said, you know, for years
you were waiting for this.

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I know it was a problem,
but there were some bumps

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in the road where the FDA was like,

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we can't approve this yet.

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Yes, those were.

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So I think that there were some issues
with like manufacturing

241
00:11:57,160 --> 00:12:01,720
and maybe like at the plant, I'm not privy
to all of the the information.

242
00:12:02,160 --> 00:12:04,840
And as you can imagine, whenever there's

243
00:12:05,440 --> 00:12:09,680
a new product coming to market
that is perhaps going to impact

244
00:12:09,960 --> 00:12:14,960
existing brands, some of those brands may,
you know, have issues.

245
00:12:14,960 --> 00:12:16,200
You know what I mean?

246
00:12:16,200 --> 00:12:18,480
So you're right in saying,
hey, check this out.

247
00:12:18,800 --> 00:12:19,560
Yeah.

248
00:12:19,800 --> 00:12:22,200
Yeah, that or this is our idea.

249
00:12:22,200 --> 00:12:24,840
Not really there. You know that. Okay, so.

250
00:12:24,840 --> 00:12:27,520
But so. Yeah. So you're not you're not.

251
00:12:27,760 --> 00:12:28,680
And I hate to cut you off,

252
00:12:28,680 --> 00:12:32,520
but you're not you're not connected
to Taxify in any way, correct?

253
00:12:32,760 --> 00:12:33,280
Oh, I'm.

254
00:12:33,280 --> 00:12:34,800
That an employee at all.

255
00:12:34,800 --> 00:12:37,840
I you know,
we have their billers in our office

256
00:12:38,080 --> 00:12:40,200
and we are a high volume practice.

257
00:12:40,200 --> 00:12:44,240
And that's what allowed me to be able
to have first access.

258
00:12:44,240 --> 00:12:48,040
But no, I have I'm not even a speaker
for them, not consulting nothing.

259
00:12:48,200 --> 00:12:48,600
Okay.

260
00:12:48,600 --> 00:12:53,040
And so as a professional, you're you're
excited about this for your own patients?

261
00:12:53,040 --> 00:12:54,320
I'm super excited.

262
00:12:54,320 --> 00:12:55,520
You know, there was a little pushback

263
00:12:55,520 --> 00:12:59,800
when we first started talking about it,
because if you were touch points

264
00:12:59,800 --> 00:13:03,480
with patients, if you're treating
you know, I mean, that can be an issue.

265
00:13:03,480 --> 00:13:06,560
But I feel like the people
who are really going to be into this,

266
00:13:06,560 --> 00:13:09,240
I mean, they're going to be loyal to you.
They trust what you're telling them.

267
00:13:09,240 --> 00:13:11,560
That's
going to be the best product for them.

268
00:13:11,560 --> 00:13:13,200
And if they're busy professionals

269
00:13:13,200 --> 00:13:15,840
and they've been on this neurotoxin
journey for a while,

270
00:13:16,320 --> 00:13:18,880
they're not going to mind
and they're going to find other reasons

271
00:13:18,880 --> 00:13:19,840
to come and see you.

272
00:13:19,840 --> 00:13:22,000
So, you know, they'll still be in.

273
00:13:22,000 --> 00:13:25,200
On the flip side of that,
you know, we've all seen recently

274
00:13:25,200 --> 00:13:28,200
where sometimes
things go awry with neurotoxins.

275
00:13:28,200 --> 00:13:31,760
So there's always going to be
the possibility of something going wrong.

276
00:13:31,760 --> 00:13:35,640
And then you have to deal with that effect
lasting for longer than it would

277
00:13:35,640 --> 00:13:37,680
with some of the shorter acting products.

278
00:13:37,960 --> 00:13:39,400
Oh, my God. Yikes.

279
00:13:39,400 --> 00:13:40,840
We're going to dig into that in a second.

280
00:13:40,840 --> 00:13:43,320
But I will tell you,
because I keep it real here with people.

281
00:13:43,320 --> 00:13:47,720
And you guys know, I have been the first
to try a lot of different things.

282
00:13:47,720 --> 00:13:52,160
I'm very excited about this, but mama is
not going to be the first to get injected.

283
00:13:52,160 --> 00:13:53,760
I'm going to wait a little bit.

284
00:13:53,760 --> 00:13:54,840
No, look, I waited.

285
00:13:54,840 --> 00:13:57,400
I waited till I was 35 to even do Botox.

286
00:13:57,720 --> 00:14:00,000
And, you know, I've been in this business
for for 20 years.

287
00:14:00,000 --> 00:14:02,600
And people, you know, in my late
twenties were like trying to love it.

288
00:14:02,880 --> 00:14:05,080
I was like, let me just lean a little bit.

289
00:14:05,080 --> 00:14:08,720
You know, there's been,
as you said, 20 years of clinical data

290
00:14:09,720 --> 00:14:10,520
for Botox

291
00:14:10,520 --> 00:14:14,160
as a Cosmo, stick it for cosmetic use.

292
00:14:14,520 --> 00:14:16,280
Mama's
going to wait a little bit on this one,

293
00:14:16,280 --> 00:14:20,040
but it really does look like
it has the potential

294
00:14:20,640 --> 00:14:23,800
to disrupt the market in a huge way.

295
00:14:24,200 --> 00:14:28,440
Now, as a doctor, you know,
you're talking about fewer touch points.

296
00:14:28,440 --> 00:14:29,720
Is that essentially right?

297
00:14:29,720 --> 00:14:31,640
What I'm hearing is
they're going to come in less

298
00:14:31,640 --> 00:14:36,360
if you have a patient coming in once every
four times a year, every three months

299
00:14:36,640 --> 00:14:39,640
or even three times a year,
which is now going to be maybe two.

300
00:14:40,480 --> 00:14:43,400
How how do you feel about that?

301
00:14:43,400 --> 00:14:48,120
Well, I mean, the Botox visits are after
you've developed your pattern

302
00:14:48,120 --> 00:14:51,200
and you get to know the patient,
they're really quick visits anyway.

303
00:14:51,200 --> 00:14:52,560
It's not like we were sitting in there

304
00:14:52,560 --> 00:14:54,240
and talking
about all these different things.

305
00:14:54,240 --> 00:14:56,320
I always leave the floor open to patients,

306
00:14:56,560 --> 00:14:58,840
but most of the time
when they're coming in for these visits,

307
00:14:58,840 --> 00:15:02,560
they're coming in to get this commodity
and then they're on about their day.

308
00:15:02,880 --> 00:15:04,680
If they really have a concern,

309
00:15:04,680 --> 00:15:07,960
they're going to bring it up
and find a way to ask you about it.

310
00:15:08,560 --> 00:15:13,040
I think that it might free them up,
actually, to kind of focus on other things

311
00:15:13,040 --> 00:15:14,520
because they don't have to always be

312
00:15:14,520 --> 00:15:18,360
thinking so much about having to come
and get their toxin so frequently.

313
00:15:18,360 --> 00:15:21,720
So I'm not too concerned about that
part of it.

314
00:15:22,320 --> 00:15:24,720
You know,
I think that establishing the relationship

315
00:15:24,720 --> 00:15:26,640
with the patient
is the most important thing.

316
00:15:26,640 --> 00:15:30,720
And to your point, I have a lot
of patients who aren't necessarily like

317
00:15:31,280 --> 00:15:33,960
knocking down the door to get it,
because if everything is going

318
00:15:33,960 --> 00:15:36,880
right with your current neurotoxin, like,
why would you change it?

319
00:15:37,200 --> 00:15:38,120
We'll get into course

320
00:15:38,120 --> 00:15:40,960
in a little bit, too,
because I think that that does factor in.

321
00:15:41,280 --> 00:15:47,320
But there is a large population
of patients who have a need for this.

322
00:15:47,320 --> 00:15:50,200
So we'll be able to get our
with all of them.

323
00:15:50,200 --> 00:15:51,000
We're going to be very

324
00:15:51,000 --> 00:15:54,720
willing participants because nothing else
is really giving them what they need.

325
00:15:54,920 --> 00:15:57,280
I mean, Michelle, let us know how it goes.

326
00:15:57,280 --> 00:15:58,440
We'll have you on next.

327
00:15:58,440 --> 00:16:00,960
Michelle, from your front desk
and I'll be asking her next.

328
00:16:01,320 --> 00:16:02,880
But now, you know, it's interesting.

329
00:16:02,880 --> 00:16:07,000
I know that a lot of people say,
you know, that you become more acclimated

330
00:16:07,000 --> 00:16:09,040
or accustomed to it.
Your body becomes used to it.

331
00:16:09,040 --> 00:16:10,480
I've heard from some doctors,

332
00:16:10,480 --> 00:16:14,040
you know, you maybe your metabolism,
certain people metabolize it.

333
00:16:14,240 --> 00:16:15,480
I'd actually believe it or not.

334
00:16:15,480 --> 00:16:19,160
Never until talking to you heard about
people who doesn't work for it all.

335
00:16:19,160 --> 00:16:23,880
So, so excitement must be we're going
to be excited for them.

336
00:16:24,040 --> 00:16:25,520
Still going to wait for it.

337
00:16:25,520 --> 00:16:26,480
You mentioned Price.

338
00:16:26,480 --> 00:16:29,480
You know, when I first heard about this,
I was like you'd be well.

339
00:16:29,680 --> 00:16:31,520
But you know, let's be honest,

340
00:16:31,520 --> 00:16:32,800
just because you're going last,

341
00:16:32,800 --> 00:16:35,200
you're going to make this
probably more expensive, right?

342
00:16:35,200 --> 00:16:37,320
I mean, they're going to get their money
from you anyway.

343
00:16:37,880 --> 00:16:40,200
Less than okay,

344
00:16:40,200 --> 00:16:44,680
if you had something that was going to
potentially disrupt the market and had a

345
00:16:45,320 --> 00:16:48,520
or an audience that was like wide awake
and ready to try it,

346
00:16:48,840 --> 00:16:51,400
why would you do it
cheaper? That just doesn't.

347
00:16:51,480 --> 00:16:53,480
Do it on sale in. America, right?

348
00:16:53,760 --> 00:16:58,440
The value is in your visits
and disruptions to your life. So

349
00:16:59,440 --> 00:17:01,680
they have not commented on price at all,

350
00:17:01,680 --> 00:17:05,560
which I think is smart,
but I expect it to cost more.

351
00:17:05,560 --> 00:17:08,800
I expect it to same as more or more.

352
00:17:09,200 --> 00:17:09,480
Yeah.

353
00:17:09,480 --> 00:17:12,560
Meaning that you're going
to outlay more money each time you do it.

354
00:17:12,560 --> 00:17:14,280
You're just going to do it your time.

355
00:17:14,280 --> 00:17:18,000
That's also going to cater to certain
folks and not work for other people.

356
00:17:18,240 --> 00:17:20,160
Some people really have to,

357
00:17:20,160 --> 00:17:23,520
you know, figure it out
for those for three or four times a year.

358
00:17:23,880 --> 00:17:27,840
And then some people want to pay
for the convenience of not having to go

359
00:17:27,840 --> 00:17:28,560
so frequently.

360
00:17:28,560 --> 00:17:30,680
It's just like anything else in life.
Yeah.

361
00:17:31,000 --> 00:17:35,040
I mean, you're absolutely right.

362
00:17:35,040 --> 00:17:36,160
Like Botox.

363
00:17:36,160 --> 00:17:40,800
And again, depending on how much you need,
can be, you know, an arm and a leg.

364
00:17:41,440 --> 00:17:44,680
So if you're adding more,
it'll be really interesting to

365
00:17:44,680 --> 00:17:45,600
see how that plays out. But

366
00:17:46,680 --> 00:17:47,080
what I'm

367
00:17:47,080 --> 00:17:49,680
hearing, you know, for rather
what I've read,

368
00:17:50,280 --> 00:17:53,000
you know, online
and what I'm hearing for you sort of echo

369
00:17:53,040 --> 00:17:54,080
the same thing which are like,

370
00:17:54,080 --> 00:17:55,960
don't think that
because you're coming in less

371
00:17:55,960 --> 00:17:59,600
than we found something that you're not
going to be spending as much, if not more.

372
00:18:00,000 --> 00:18:00,360
You're right.

373
00:18:00,360 --> 00:18:04,280
What you're saving in is that convenience
of not having to go down

374
00:18:04,280 --> 00:18:06,600
to your doctor's office. Exactly.

375
00:18:07,200 --> 00:18:11,120
In our dermatology community, that was a
lot of the initial conversation.

376
00:18:11,120 --> 00:18:13,920
Will, if it's cheaper
and they're coming in less,

377
00:18:13,920 --> 00:18:16,000
then I'm not sure if I can get on board
with that.

378
00:18:16,000 --> 00:18:16,280
Right.

379
00:18:16,280 --> 00:18:19,800
But, you know, because that just doesn't
make sense from a business standpoint.

380
00:18:19,800 --> 00:18:23,240
But I just don't think
that's going to be the case right now.

381
00:18:23,240 --> 00:18:26,480
Do you think, you know, as a professional
and you mentioned

382
00:18:26,520 --> 00:18:30,000
you've done other injection trials before,

383
00:18:31,040 --> 00:18:31,520
do you feel

384
00:18:31,520 --> 00:18:34,400
like, you know, for the
for the general public that there's enough

385
00:18:34,800 --> 00:18:38,400
safety background for those people
who are going to be brave enough to

386
00:18:38,880 --> 00:18:39,600
to go for this?

387
00:18:39,600 --> 00:18:44,720
The first time I do
the FDA really has stringent criteria

388
00:18:44,720 --> 00:18:47,520
for approval of these types
of medications.

389
00:18:47,880 --> 00:18:51,400
And in this instance,
I really think that this prolonged period

390
00:18:51,400 --> 00:18:55,560
has really put them through the ringer,
maybe even more so than other companies,

391
00:18:56,360 --> 00:18:59,600
because it is not a human alpha
women protein.

392
00:18:59,600 --> 00:19:03,160
It probably, you know, confers

393
00:19:03,160 --> 00:19:05,640
less of an overall risk, I would say.

394
00:19:06,360 --> 00:19:08,160
But there is still that area
of the unknown.

395
00:19:08,160 --> 00:19:10,080
Whenever you're innovating,
you're going to be

396
00:19:10,080 --> 00:19:13,640
at that point where you know,
you just have to kind of see what happens.

397
00:19:13,920 --> 00:19:19,080
Yeah, but no, I have no qualms or concerns
about the safety of the product.

398
00:19:19,200 --> 00:19:19,760
Got it.

399
00:19:19,760 --> 00:19:22,800
By the way, I know my father
listens to this and he's probably so

400
00:19:22,800 --> 00:19:25,680
happy that for the first time
because I'm always like, I'll try that.

401
00:19:26,160 --> 00:19:27,040
Sign me up that.

402
00:19:27,040 --> 00:19:29,040
I'm like, Daddy,
don't worry, I'm going to wait.

403
00:19:29,040 --> 00:19:32,880
I know he's listening
and I know he's happy right now.

404
00:19:32,880 --> 00:19:37,320
So, you know,
you mentioned before, though, so DAX ify,

405
00:19:37,560 --> 00:19:39,600
you have their fillers.

406
00:19:39,600 --> 00:19:43,320
Yes. Oh, so I never heard of
I've never heard of DAX inside before.

407
00:19:43,320 --> 00:19:45,680
Okay. So so this is like a brand new.

408
00:19:46,360 --> 00:19:49,640
You know, so DAX
by is, is the brand of their neurotoxin.

409
00:19:49,640 --> 00:19:53,840
But the company,
the parent company is called Riverdance.

410
00:19:54,040 --> 00:19:54,840
Okay.

411
00:19:54,840 --> 00:19:56,160
And you've tried their fillers.

412
00:19:56,160 --> 00:19:58,280
Oh, we've had their fillers
for a while. Yes.

413
00:19:58,280 --> 00:20:01,600
They have a collection
of fillers called RH A

414
00:20:02,600 --> 00:20:04,920
and RH two, three and four.

415
00:20:04,920 --> 00:20:06,640
And then they just launched one.

416
00:20:06,640 --> 00:20:09,960
That is a lighter filler for feeling
very fine lines,

417
00:20:09,960 --> 00:20:12,240
very superficially called density.

418
00:20:12,960 --> 00:20:16,680
I don't know why they did go with RH one,
that's what it's called in Canada,

419
00:20:16,760 --> 00:20:20,480
but for whatever reason it's called
for density here in the United States.

420
00:20:20,480 --> 00:20:24,680
They have a beautiful new headquarters
in Nashville downtown

421
00:20:25,440 --> 00:20:29,280
that I have had a chance to visit because
it's my alma mater is in Nashville, too.

422
00:20:29,280 --> 00:20:31,560
So I stopped by it, my 20 year reunion.

423
00:20:31,560 --> 00:20:34,960
And yeah,
they just have state of the art facilities

424
00:20:34,960 --> 00:20:38,240
with some really cool rooms
where you can do live

425
00:20:38,240 --> 00:20:41,480
demonstrations and have it,
you know, simulcast out.

426
00:20:41,480 --> 00:20:42,960
It's really kind of neat.

427
00:20:42,960 --> 00:20:44,840
I'm laughing. I'm like, Yeah,
of course they do.

428
00:20:44,840 --> 00:20:47,200
Because they're like,
We are about to be rolling in it.

429
00:20:47,560 --> 00:20:50,160
Let's show the world what we're hope.

430
00:20:50,160 --> 00:20:51,200
They're, you know,

431
00:20:51,200 --> 00:20:55,040
interesting thing you mentioned before
and I do like to be serious on here,

432
00:20:55,040 --> 00:20:57,960
you know, even with Botox,
even with using neuro modulator.

433
00:20:57,960 --> 00:21:00,560
ZM And the other ones that
we were talking about is Port

434
00:21:02,400 --> 00:21:03,800
in the wrong hands.

435
00:21:03,800 --> 00:21:07,080
Things can go wrong

436
00:21:07,080 --> 00:21:08,440
for Doxy.

437
00:21:08,440 --> 00:21:12,120
From what I understand right now
it is only FDA approved for the.

438
00:21:12,120 --> 00:21:13,560
Is it good?

439
00:21:13,640 --> 00:21:15,920
Beller Yeah, well,

440
00:21:15,920 --> 00:21:18,120
I have braces,
so it's really hard for me to say.

441
00:21:18,120 --> 00:21:19,920
But the lines in the forehead,
you're 11 lines.

442
00:21:19,920 --> 00:21:22,560
It's not approved for anywhere else.

443
00:21:23,280 --> 00:21:25,320
Yeah, but you know. Yeah, you know.

444
00:21:25,880 --> 00:21:28,640
You know, I mean, they all start off
with the approval there.

445
00:21:28,640 --> 00:21:33,000
I think Botox just got approval for crow's
feet like two or three years ago.

446
00:21:33,280 --> 00:21:37,600
Oh, it's the only neurotoxin
that's approved for the big three areas.

447
00:21:37,600 --> 00:21:40,560
But we all know that we use Botox
all over the face.

448
00:21:41,160 --> 00:21:42,360
I mean, I did it on the chin.

449
00:21:42,360 --> 00:21:44,920
I do it here,
here, all over here. Exactly.

450
00:21:45,240 --> 00:21:47,640
So I don't think that's really going to be
an issue.

451
00:21:48,000 --> 00:21:53,480
Your point about injector is huge, though,
because understanding the nuances

452
00:21:53,480 --> 00:21:57,920
between the different products
and what their capabilities are and what

453
00:21:57,920 --> 00:22:02,040
the needs of the patient are, all of that
factors into a successful treatment.

454
00:22:02,040 --> 00:22:04,000
It's not just the product.

455
00:22:04,000 --> 00:22:06,040
So that knowledge is really important.

456
00:22:06,200 --> 00:22:06,840
And I think that's

457
00:22:06,840 --> 00:22:10,840
what all of us are going to be gaining
when we get acclimated

458
00:22:10,840 --> 00:22:15,360
to how it behaves, what
the dosing schedule is going to be like.

459
00:22:15,360 --> 00:22:17,280
Because there's also going
to be a difference in dosing

460
00:22:17,280 --> 00:22:18,600
that we're going to have to get used to.

461
00:22:18,600 --> 00:22:20,880
And that's another reason
I think they're being very cautious

462
00:22:21,240 --> 00:22:22,960
about how they roll this out.

463
00:22:22,960 --> 00:22:23,880
So yeah.

464
00:22:23,880 --> 00:22:24,240
We are.

465
00:22:24,240 --> 00:22:24,560
Yeah.

466
00:22:24,560 --> 00:22:29,840
Well, so Botox is 20 units in the LaBella

467
00:22:30,680 --> 00:22:34,000
and Dax's approved dosage is 40 units.

468
00:22:34,440 --> 00:22:37,560
Now, they you can't compare unit to unit.

469
00:22:37,920 --> 00:22:41,400
And now you look at it on a kill
adult and basis, they're equal.

470
00:22:42,120 --> 00:22:46,400
But there's going to be a difference
just like this port is actually dosed

471
00:22:46,400 --> 00:22:49,920
two and a half times
the number of Botox units.

472
00:22:49,920 --> 00:22:52,360
So it gets kind of a little
a little different.

473
00:22:52,640 --> 00:22:53,280
Now, I know

474
00:22:54,720 --> 00:22:55,080
from what I

475
00:22:55,080 --> 00:22:58,320
understand by Botox,
it always has to be diluted as well.

476
00:22:58,320 --> 00:23:00,880
Right. You can't inject pure Botox.

477
00:23:00,880 --> 00:23:03,000
There's a certain dilution
that happens with it.

478
00:23:03,000 --> 00:23:05,840
Is there a dilution with.

479
00:23:05,880 --> 00:23:07,560
So that's to be determined.

480
00:23:07,560 --> 00:23:10,120
But let's okay,
so let's back up a little bit.

481
00:23:10,320 --> 00:23:13,240
Dilution and reconstitution are

482
00:23:13,600 --> 00:23:16,280
two separate things
that I think sometimes get conflated.

483
00:23:16,760 --> 00:23:21,680
These products that we have available
to us now index if I will be one of them

484
00:23:22,080 --> 00:23:27,440
all come in a vial as a like a dry powder
that's on the bottle.

485
00:23:27,680 --> 00:23:31,640
We introduce bacteria, static sailing
or some other

486
00:23:31,920 --> 00:23:35,640
liquid to release it,
to allow it to be injected.

487
00:23:35,800 --> 00:23:37,800
So there s the reconstitution.

488
00:23:37,800 --> 00:23:41,320
The dilution is really up
to the individual

489
00:23:41,600 --> 00:23:44,440
doctor to determine

490
00:23:44,440 --> 00:23:46,320
and a lot of factors go into that.

491
00:23:46,320 --> 00:23:50,520
So I use a 2 to 1 dilution with Botox
because I like the way that it spreads,

492
00:23:50,800 --> 00:23:53,640
but also the needles and syringes
that I use

493
00:23:53,880 --> 00:23:57,680
that make it more comfortable
for patients have such small

494
00:23:59,560 --> 00:24:01,680
measurement, you know, ticks

495
00:24:01,680 --> 00:24:05,640
that my fingers
just do better with the 2 to 1 dilution.

496
00:24:05,720 --> 00:24:06,040
Gotcha.

497
00:24:06,040 --> 00:24:08,400
My partner, Dr. Luck, Katie. Lucky it.

498
00:24:08,400 --> 00:24:10,080
She prefers a 1 to 1.

499
00:24:10,080 --> 00:24:14,880
So understanding the nuances of spread,
understanding how with the push

500
00:24:14,880 --> 00:24:18,440
is going to feel, all of that goes
into determining the dilution.

501
00:24:18,440 --> 00:24:20,880
And I think that there's
an acceptable range of dilution

502
00:24:20,880 --> 00:24:24,600
that we all agree
is, you know, just sort of discretionary.

503
00:24:24,840 --> 00:24:27,600
And then there's a level of dilution
that is like, okay,

504
00:24:27,600 --> 00:24:30,000
now you're just trying to stretch it and.

505
00:24:30,000 --> 00:24:33,240
Well, and I'm going to take this moment
to be a PSA.

506
00:24:33,240 --> 00:24:36,120
I am not a doctor, but you've heard me
say it again and again.

507
00:24:36,480 --> 00:24:38,840
Botox, do not get the Groupon.

508
00:24:39,280 --> 00:24:42,480
Get the Groupon for your workout classes.

509
00:24:42,480 --> 00:24:44,280
Get the Groupon for your shoes.

510
00:24:44,280 --> 00:24:49,920
I mean, do not do it when it comes to
and injecting neurotoxins.

511
00:24:49,920 --> 00:24:53,440
I mean, you just don't want to do it
because you look at the end of the day,

512
00:24:54,760 --> 00:24:56,080
maybe places offer a deal.

513
00:24:56,080 --> 00:24:59,880
But from what I've understood in talking
to you, get what you pay for, right?

514
00:25:00,520 --> 00:25:01,840
Or so.

515
00:25:01,840 --> 00:25:04,600
And if they dilute it too much,
you can have really bad, you know,

516
00:25:04,640 --> 00:25:08,320
like my daddy always said, you don't say
here's two areas you don't save money on.

517
00:25:08,560 --> 00:25:11,960
You don't try to save money
on your birth control or your surgery

518
00:25:12,600 --> 00:25:14,440
or any cosmetic surgery. Right.

519
00:25:14,440 --> 00:25:16,480
Like your dad, he sounds super wise.

520
00:25:16,680 --> 00:25:17,480
That's what he's like.

521
00:25:17,480 --> 00:25:20,040
These are the two areas, honey,
not to save money in

522
00:25:20,760 --> 00:25:23,000
because you get what you pay
for, so. Okay.

523
00:25:23,000 --> 00:25:26,440
So when do you anticipate
now that we're going to start to see

524
00:25:26,720 --> 00:25:29,640
roll out of of vaccine in the US here.

525
00:25:29,840 --> 00:25:30,240
All right.

526
00:25:30,240 --> 00:25:34,080
So what I understand and this is nothing
permanent might be some secret

527
00:25:34,080 --> 00:25:37,480
and whatever it hasn't been verified
before.

528
00:25:37,480 --> 00:25:40,680
And I understand there's
going to be a very select group of doctors

529
00:25:40,680 --> 00:25:45,600
that gets it in December when they train.

530
00:25:46,080 --> 00:25:47,120
Okay.

531
00:25:47,120 --> 00:25:51,320
And then the next group,
which is going to be a little bit larger,

532
00:25:51,960 --> 00:25:54,560
will be sometime in March.

533
00:25:54,840 --> 00:25:55,680
Okay.

534
00:25:55,720 --> 00:25:59,200
And then it won't be available
to the masses

535
00:25:59,200 --> 00:26:02,520
until the summertime of 2023.

536
00:26:02,920 --> 00:26:04,760
So they're being smart
and they're making everybody

537
00:26:04,760 --> 00:26:08,480
go to their location and train
because they don't want bad press.

538
00:26:08,800 --> 00:26:11,200
They don't want bad press.
And it's so easy these days.

539
00:26:11,200 --> 00:26:14,120
It doesn't end with there's
just so many people out here

540
00:26:14,120 --> 00:26:17,400
injecting these days
that it's hard to really contain that.

541
00:26:17,800 --> 00:26:20,600
So I think they're doing it
in a very smart way.

542
00:26:21,440 --> 00:26:23,560
We'll be able to get so much information

543
00:26:23,840 --> 00:26:28,200
knowing that they're relying
on very experienced master injectors.

544
00:26:28,640 --> 00:26:30,000
Everybody calls themselves that.

545
00:26:30,000 --> 00:26:32,000
But, you know, we'll see who's to

546
00:26:33,480 --> 00:26:35,160
in this first three months and that.

547
00:26:35,160 --> 00:26:37,000
What is your what is your it?

548
00:26:37,000 --> 00:26:39,000
I go into December 4th. Oh, wow.

549
00:26:39,000 --> 00:26:41,160
You are the first today.

550
00:26:41,160 --> 00:26:43,200
All right, Dr. Hartman?

551
00:26:43,200 --> 00:26:44,600
Yeah. Oh, my God. Wait.

552
00:26:44,600 --> 00:26:46,640
I mean, have the phones
been ringing off the hook?

553
00:26:47,040 --> 00:26:50,440
Listen, I have been telling
all my patients who I think would be

554
00:26:50,440 --> 00:26:53,560
interested, you know,
because they are looking for options.

555
00:26:53,560 --> 00:26:56,200
So it's my responsibility to share that.

556
00:26:56,200 --> 00:26:59,640
But yeah, we anticipate
lots of demand when it.

557
00:26:59,640 --> 00:27:03,200
Comes, oh, my gosh,
I'm going to be watching this like a hawk.

558
00:27:03,400 --> 00:27:05,840
You know,
I have more questions before we go.

559
00:27:05,840 --> 00:27:06,640
But do you have

560
00:27:06,640 --> 00:27:09,640
are you can be posting this on Instagram
like where can we watch yours?

561
00:27:09,680 --> 00:27:10,320
Yeah.

562
00:27:10,320 --> 00:27:13,040
You can totally say, yeah,
I've given a little bit of a sneak peek

563
00:27:13,040 --> 00:27:17,800
already, did a little media
and got some information on like that.

564
00:27:17,800 --> 00:27:20,880
I've share with you guys today
about the peptide, why it's different.

565
00:27:21,560 --> 00:27:24,840
Some of it is just my own commentary
and what I think about pricing,

566
00:27:24,840 --> 00:27:26,600
but I think I'm on it with that.

567
00:27:26,600 --> 00:27:28,920
So yeah,
I can't wait to share it with you guys.

568
00:27:28,920 --> 00:27:31,240
If you all follow along,
you will learn everything

569
00:27:31,240 --> 00:27:34,400
that you want to know
so that when the time comes

570
00:27:34,600 --> 00:27:39,080
you can feel confident about perhaps
trying it or sticking with your product,

571
00:27:39,080 --> 00:27:39,600
you know?

572
00:27:39,600 --> 00:27:43,600
I mean, hey, everybody's not going to be
a candidate for this product.

573
00:27:43,600 --> 00:27:45,120
And, you know, that's okay.

574
00:27:45,120 --> 00:27:45,800
It's good to have.

575
00:27:45,800 --> 00:27:48,240
Options as it launched anywhere else.

576
00:27:48,240 --> 00:27:50,320
But actually, where's your app?
What's your Instagram?

577
00:27:51,040 --> 00:27:52,800
Yeah, that's Dr. Cory Hartman.

578
00:27:52,800 --> 00:27:54,520
C.A.R.E. Hartman.

579
00:27:54,520 --> 00:27:56,000
Yeah. Corey Hartman. Okay. Yeah.

580
00:27:56,000 --> 00:27:57,560
Has it launched anywhere else already?

581
00:27:57,560 --> 00:28:01,120
That's the other thing that is cool
and unique about this product.

582
00:28:01,120 --> 00:28:04,880
So the other neurotoxins, Europe
gets everything 10 to 15 years

583
00:28:04,880 --> 00:28:06,080
ahead of us, right?

584
00:28:06,080 --> 00:28:08,680
So all the others launched their first
and then came here.

585
00:28:08,720 --> 00:28:12,600
This is the first one that's launching
even ahead of Canada. Wow.

586
00:28:12,600 --> 00:28:13,040
Okay.

587
00:28:13,040 --> 00:28:17,640
Well, look,
I've got to be determined to be seen.

588
00:28:18,200 --> 00:28:21,080
Before we let you go, though,
is there anybody you know, we've talked

589
00:28:21,120 --> 00:28:23,440
about all that
wonderful things about this.

590
00:28:23,480 --> 00:28:26,240
Is there anybody who like
because this is a different

591
00:28:26,480 --> 00:28:29,600
sort of mechanism of action
who should not use this?

592
00:28:30,120 --> 00:28:30,840
Yeah.

593
00:28:30,840 --> 00:28:33,560
So I can't really think of anybody
offhand.

594
00:28:33,560 --> 00:28:37,440
That would be contraindicated
to trying this because it's a peptide

595
00:28:37,440 --> 00:28:40,880
peptides are generally very safe
and well tolerated by everyone.

596
00:28:41,760 --> 00:28:44,000
I think that we're going to determine
that group

597
00:28:44,040 --> 00:28:48,120
based upon the performance of the product
once it gets into our hands.

598
00:28:48,360 --> 00:28:48,560
Right.

599
00:28:48,560 --> 00:28:52,320
So I don't there's nobody that I can say
absolutely should not try it.

600
00:28:52,320 --> 00:28:56,920
It might get in to practice
and we realize that it's a little heavier

601
00:28:56,920 --> 00:29:02,400
or a little lighter or a little more
restricted or whatever than we realize.

602
00:29:02,400 --> 00:29:04,760
And that might rule out some groups.

603
00:29:04,760 --> 00:29:10,440
But right now it looks like it's wide open
for anyone who wants to try it.

604
00:29:11,800 --> 00:29:14,800
Well,
I mean, I am waiting with bated breath

605
00:29:14,800 --> 00:29:18,440
because I feel like, again,
this is the first thing that really

606
00:29:18,440 --> 00:29:21,840
has the potential
to totally disrupt the market.

607
00:29:21,840 --> 00:29:25,800
And like I said, Botox alone,
not all of its other versions.

608
00:29:26,040 --> 00:29:29,640
I know Botox made $4.7 billion

609
00:29:29,640 --> 00:29:32,840
last year for its parent company.

610
00:29:32,840 --> 00:29:36,040
So this has incredible potential.

611
00:29:36,840 --> 00:29:39,040
You know, keep in mind,
we keep it real here.

612
00:29:39,240 --> 00:29:41,400
You know, you said it earlier on.

613
00:29:41,400 --> 00:29:42,480
And I just want to point that out.

614
00:29:42,480 --> 00:29:45,120
If you are one of the first people
to try this, if things go wrong,

615
00:29:45,320 --> 00:29:47,120
you're going to have to wait a long time.

616
00:29:47,120 --> 00:29:50,360
You know, if things go wrong with Botox,
we've all seen it.

617
00:29:50,520 --> 00:29:53,000
You got to just wait it out.

618
00:29:53,000 --> 00:29:54,280
It's not permanent damage.

619
00:29:54,280 --> 00:29:59,280
But trust me, 3 to 5
months can feel like eternity.

620
00:29:59,600 --> 00:30:02,160
If you've got something wrong,
can't be longer.

621
00:30:02,160 --> 00:30:05,200
So six to nine some people.

622
00:30:05,200 --> 00:30:07,880
And the studies
were even as long as nine months,

623
00:30:08,080 --> 00:30:12,200
which sounds great
until it doesn't sound great.

624
00:30:12,200 --> 00:30:14,040
It doesn't sound great.

625
00:30:14,040 --> 00:30:16,600
Well, look, we love this.

626
00:30:16,600 --> 00:30:18,880
I'm so honored to have you on. Dr.

627
00:30:18,880 --> 00:30:20,360
Hartman, you were so eloquent.

628
00:30:20,360 --> 00:30:25,200
I can tell that you are,
you know, really excited about this book,

629
00:30:25,200 --> 00:30:26,040
but approaching it

630
00:30:26,040 --> 00:30:29,440
with all of the precautions,
you would want your doctor to do that.

631
00:30:30,000 --> 00:30:31,360
You know,
people want to know more about you.

632
00:30:31,360 --> 00:30:34,800
If they're in the Birmingham area
and they want to come visit you,

633
00:30:35,000 --> 00:30:36,360
what's the best way to find you?

634
00:30:37,600 --> 00:30:40,360
Oh, we would love that.

635
00:30:40,360 --> 00:30:45,960
By our well website is SkinWellness.com
We are in Birmingham, Alabama.

636
00:30:46,720 --> 00:30:47,280
I'm Dr.

637
00:30:47,280 --> 00:30:48,080
Corey Hartman.

638
00:30:48,080 --> 00:30:50,720
And Skin Wellness
Dermatology across all platforms.

639
00:30:50,720 --> 00:30:54,320
Well, you know, before we lose you again,
I don't know if you heard my little joke

640
00:30:54,360 --> 00:30:57,200
about, you know, being frozen
and it feels like an eternity.

641
00:30:57,480 --> 00:31:00,800
I want to thank you so much Dr. Hartman.

642
00:31:00,800 --> 00:31:03,400
You know, if you have questions
you want me to pass on to Dr.

643
00:31:03,400 --> 00:31:04,040
Hartman to see?

644
00:31:04,040 --> 00:31:05,240
I'm always happy to do that.

645
00:31:05,240 --> 00:31:08,800
You can email me at
hello@artbeautypocast.com You can find us

646
00:31:08,800 --> 00:31:11,800
on Facebook Instagram
and YouTube @artbeautypodcast

647
00:31:12,080 --> 00:31:14,760
and is always we will see you next Tuesday

648
00:31:15,000 --> 00:31:17,640
and a year from now,
maybe you'll be a little less frozen.

649
00:31:18,040 --> 00:31:19,920
Thanks for being on.

650
00:31:19,920 --> 00:31:22,320
Thank you.

651
00:31:27,840 --> 00:35:17,160
All right.

652
00:35:17,160 --> 00:35:17,560
All right.
