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Hi, everyone. This is Laura Dierda with Becker's

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Healthcare. Thank you for tuning in to the

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Becker's Healthcare podcast series. We are thrilled today

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to be joined by doctor Holly Urban, vice

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president of business development strategy and clinical effectiveness

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at Walter's Kloer Health. Doctor Urban, it's a

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pleasure to have you on the podcast today,

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and thank you so much for joining us.

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We are excited to dive into your journey

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and experience.

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Thanks so much, Laura. I really appreciate the

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opportunity

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to, speak with you all.

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Fantastic. Well, let's dive right in. Doctor Urban,

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could you introduce yourself and your work in

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the health care to our listeners?

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Yeah. Absolutely. I'm Holly Urban. I am a

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pediatrician by training.

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I practiced in primary care pediatrics for several

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years before starting a second career in health

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care IT, and I've been in health care

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IT for about 15 years.

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In multiple leadership roles, I was vice president

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of product management at McKesson Horizon Clinicals,

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and then recently was CMIO at Oracle Cerner

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for their federal business.

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And I started working at Wolters Kluwer this

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year in,

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and my role in business development

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is really focused on innovation opportunities and how

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we do innovation,

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with some of Walter Scott's most influential and

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important products, which are our,

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up to date product,

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our up to date patient engagement, and, up

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to date Lexi drug content, formerly known as

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Lexi Comp.

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People who don't know the UpToDate product, it

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is probably the most used clinical decision support

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product used by physicians and other clinical users

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across the US. We have about 2,400,000,

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clinicians who use UpToDate,

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and clinicians really trust the content. They know

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that our 74100

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medical experts

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who are leaders in the field,

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they curate the content. They author the content

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as well as it's being updated

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every business day. During COVID, it was every

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day.

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So it's constantly being updated with the most

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important, most recent evidence. And so the our

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customers who use the content have a lot

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of trust in the content.

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So we did a big study of of

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providers

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this year that said, how do you think

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about generative AI tools? Since I'm in innovation

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with UpToDate, this is something I think about

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a lot.

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And, you know, we did learn that over

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40% of these users are are ready to

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use generative AI. And that's been a change

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over the past year. So that's been increased

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quite a bit, 68%

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over they're they have changed their views on

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generative AI since last year.

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But 91%

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said that any generative AI tool, they would

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wanna know where the materials were sourced and

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and know that they were created by physicians

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and medical experts,

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and they'd also want their vendors of j

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Gen AI tools to be transparent where the

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information came from.

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So

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as we think on up to date clinical

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decision support,

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we we know that there's some limitations. And

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and I'm and I'm not talking about,

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some of the really amazing tools out there

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that are all about physician efficiency. So, like,

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you know, some of the ambient listening or

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chart summarization tools. What I'm really talking about

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is

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AI tools that are focused on, clinical decision

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support, like diagnostics

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decision support or therapeutic decision support. And, you

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know, to be totally frank, we see a

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lot of limitations.

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You know, hallucinations are 1. I mean,

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even today, it continues to hallucinate. And when

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you're talking about making care decisions for a

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patient,

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that level of risk is just unacceptable for

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most clinicians. Again, it comes back to trust.

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So if if you're if you're concerned that

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there may be a hallucination, how can you

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possibly trust what the what the LM is

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telling you? The other is the inconsistency

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of the response. You ask the same question

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3 days in a row, you could get

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different answers from an LLM, which again,

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I think would impact trust. Right? So it

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how can you trust what they're really telling

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you if you're not getting a consistent response?

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And then the final, and this is something

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that I think about a lot is,

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is patient context. So

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one example is so let's say you,

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put it into an LLM,

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there's a patient who has a urinary tract

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infection, a bladder infection,

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and they're allergic to penicillin, so what antibiotic

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should I use?

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And you'll get a response, it's probably a

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fluoroquinolone.

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Great. I've got my answer. I'm gonna go

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write a prescription for a fluoroquinolone

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for my patient.

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Well, the challenge there is you don't have

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the L and M didn't have all the

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patient context. What if it's a pregnant patient?

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Patient is pregnant. You do not wanna be

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prescribing a fluoroquinolone.

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What if it's a child?

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Again, you do not wanna be prescribing fluoroquinolone.

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What if it's a recurrent bladder infection? What

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if it's a complicated bladder infection? There's just

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a lot of patient context that's there that

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you don't get in that LLM response,

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and that makes it really challenging again to

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trust what the response you're getting. And that's

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why at UpToDate is we're looking at some

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of these models is we're also really gauging

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how do we make sure that

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no hallucinations at 0 risk, so it's really

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grounded in the up to date content,

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as well as giving those nudges or giving

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that guidance to say,

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have you really thought about all the patient

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contextual factors?

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Well, it's fascinating to hear. You know, there's

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some really impressive results and things you're talking

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about that make a big difference in the

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clinical space. So

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excited for what's ahead, but I know as

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you mentioned, still things to work through. Yes.

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More hospitals and health systems right now are

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also getting serious about value based care. As

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a former care provider for pediatric patients, how

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do you view this shift,

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toward more proactive preventative care? Yeah. It's it's

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really interesting to me. So as a pediatrician,

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I mean, you're sort of grounded

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in proactive preventative care from the beginning. It's

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really the core of pediatric medicine.

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I mean, we

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do growth charts where you measure a patient's

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growth against the growth chart. And if they

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fall off the growth chart, that may be

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a sign of a problem. We do developmental

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screening to make sure kids are hitting their

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develop developmental milestones.

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We do anticipatory guidance to say, hey. Have

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you thought of you know, are you doing

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the right diet nutrition for your patients? And,

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of course, we do immunizations

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to make sure that you're preventing disease. So,

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so having that sort of proactive

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preventative mindset is very core to what I

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always did and what all pediatricians do. And

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so when you think about the broader scale

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of health care, you know, most physicians aren't

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trained in that model. It's really more, I'm

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gonna treat the patient that's sitting across from

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me in my office or that's in the

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hospital

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bed. So you're not thinking about the patient

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the other

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364 days of a year when you're not

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seeing them because there aren't economic drivers to

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do that, frankly.

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So I really that's why I've been an

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early proponent of moving toward the more value

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based care to really understand how do what

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do we need to do for our patients

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in those other 364

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days so that they aren't consuming health care

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services, so they are staying healthy, so they

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don't have to come see me. And that's

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what value based care is all about.

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That makes a lot of sense. You know,

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it is amazing to hear a great vision.

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And I I love the idea of pediatrics

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being so proactive,

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from the get go and then instilling that

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within other areas of the health care system.

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How can health care

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leverage systems thinking and design systems that facilitate

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the delivery of the highest quality care to

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generate better outcomes,

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increase safety, and improve efficiency,

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especially in this move towards value based care?

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Yeah. Those things these things are very intertwined.

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So what I would argue is that in

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how we call our health care system,

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it isn't a system at all.

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It's a very broken, fragmented,

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siloed

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with very, sort of perverse economic incentives.

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And and the data shows that the system

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isn't working. You know, if you look at

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the Commonwealth Fund,

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every year they publish that we spend

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3 to 4 times more in our health

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care dollars

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than other developed countries. And yet our outcomes

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are significantly worse. I mean, it's very, very

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sobering

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that we are just we are just not

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getting value for the health care dollars that

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we spend.

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And so that's why I've been talking a

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lot about how systems thinking needs to be

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addressed. Because if you if you throw in

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other issues like, you know, workforce burnout

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and,

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and bias, like, if you don't think about

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those issues with the systems thinking approach, it's

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almost impossible, because they're systemic issues. So how

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do you fix it without taking a systematic

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approach into a broken system? So

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what systems thinking is, it's all about designing

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a system to meet the outcomes you're looking

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for.

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So that's like, in health care, obviously, it's

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better care at lower costs.

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And, you know, so many health care systems

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do process improvement or quality improvement

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where the focus is really on fixing people.

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Like, how do you change their mindsets or

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how do you change their workflow? But, again,

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I'd argue that if the system that they're

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working in isn't designed to meet the outcome

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you want, just trying to fix the people

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is not gonna lead to sustainable or systemic

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change. So that's why I really advocate for

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this broader systems thinking to make sure that

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you're designing the entire system and all of

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the people in it and all the processes

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and all the technology

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to meet your intended outcomes. And there's an

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interesting,

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so the leaders at the IHI published an

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article in the Harvard Business Review in July,

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that talks about this. So if anybody wants

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to read more about it, I highly recommend

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the article. It's really well done. And they

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call out, James Clear's book, Atomic Habits, and

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he says, you do not rise to the

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level of your goals. You fall to the

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level of your systems.

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That's fascinating. What a poignant,

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thing to keep in mind in the health

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care space and truly

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overall just a really important,

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lesson, to think about on a regular and

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daily basis. Systems are definitely make a difference.

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Now I know you're currently working on a

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publication that's going to highlight the generative AI's

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potential in health care and practical applications for

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clinicians.

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Can you share your insights on how AI

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can disrupt the traditional health care models

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and what challenges health care organizations should really

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be aware of? Yeah. Absolutely. So the, the

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textbook is Digital Health AI and Generative AI,

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a concise practical guide for clinicians. It's gonna

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come out,

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Springer Nature's publishing it edited by Terri Adiram

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in in 2025.

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And my chapter is on implementing

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IA tools.

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Again, you have to take a systems thinking

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approach when you're implementing these tools. It's not

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a very simple plug and play, like, I'm

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gonna plug in an EKG machine,

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get a patient the leads on, and I'll

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get an EKG out of it. It's far

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more complex than that. You really need to

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think about all of the people and processes

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that are gonna be involved with the tool

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itself.

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So just to take an example, let's talk

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about,

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a a patient inbox where you're where you're

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using AI to do triage of patient messages.

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So I would say taking a systems thinking

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approach means you start with what metrics are

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you gonna follow to know that you're going

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to,

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meet the outcomes you're looking for, and who's

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tracking them, and who's owning them, and who's

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reporting out on those metrics,

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what resource

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is managing those,

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triage messages,

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how are messages

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rerouted to other clinical users when needed, and

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what are the criteria to reroute,

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and and auditing? So are there any messages

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falling through the crack? That's that's to cover

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risks.

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Is there AI drift? I mean, we know

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a lot about these AI models that they're

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trained in, you know, with the vendor side,

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but once they get into patient population models,

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that they can drift and they can change.

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So who the only way to really

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see that happening is through audits. And then

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finally, addressing issues of bias. I mean, doing

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subgroup population analysis to make sure that you're

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not seeing any bias in the in the

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AI response. And then finally, the most important

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is governance. Right? Who has governance over all

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of that? So you really need to be

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thinking people process and technology when you're implementing

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these tools.

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That's fascinating to hear and certainly

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a very poignant reminder in terms of how

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you can really

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most effectively implement these tools, get them out

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to the broader system, and make sure that

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they're used and optimized correctly. I know that

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can be a big challenge, and a lot

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goes into it. So

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fascinating to hear. Is there anything else you'd

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like to share with our audience that we

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haven't already touched on? No. I think that's

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great. Thank you again for the opportunity to

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chat today, and, I enjoyed the conversation.

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Doctor Urban, thank you so much for joining

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me on the podcast today. It has been

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such a pleasure speaking with you. I'd also

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like to thank our podcast sponsor, Wolters Kluwer

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Health. You can tune in to more podcasts

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from Becker's Healthcare by visiting the podcast page

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at beckershospitalreview.com.